Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Miaoyan Wei"'
Autor:
Miaoyan Wei, Rujiao Liu, Yunyun Xu, Xiaobing Chen, Chao Liu, Xueli Bai, Xiaochen Zhang, Shuiping Gao, Jialin Li, Zhen Sheng, Jianpo Lian, Wenliang Wang, Jian Zhang, Si Shi, Jin Xu, Xianjun Yu
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Background Chemotherapy remains the standard first-line treatment for pancreatic adenocarcinoma, but with limited efficacy. We aimed to explore the feasibility of adding the PARP inhibitor fuzuloparib to mFOLFIRINOX in the locally advanced/m
Externí odkaz:
https://doaj.org/article/cef3d052c08f444f99a82d9527d12961
Autor:
Jialin Li, Si Shi, Jiang Liu, Chen Liang, Jie Hua, Qingcai Meng, Hang Xu, Miaoyan Wei, Bo Zhang, Jin Xu, Wei Wang, Xianjun Yu
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-14 (2023)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy. Radical surgical resection offers the only potential cure. There is increasing agreement that radical antegrade modular pancreatosplenectomy (RAMPS) may be
Externí odkaz:
https://doaj.org/article/b65320f33db541288534c219377a4434
Autor:
Siyuan Lu, Jie Hua, Jiang Liu, Miaoyan Wei, Chen Liang, Qingcai Meng, Bo Zhang, Xianjun Yu, Wei Wang, Jin Xu
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-19 (2022)
Abstract Background RNA methylation refers to a form of methyl modification in RNA that modulates various epigenetic alterations. Mounting studies have focused on its potential mechanisms in cancer initiation and progression. However, the prognostic
Externí odkaz:
https://doaj.org/article/c3844b706a344a1daa39bf39350770cd
Autor:
Siyuan Lu, Jie Hua, Jin Xu, Miaoyan Wei, Chen Liang, Qingcai Meng, Jiang Liu, Bo Zhang, Wei Wang, Xianjun Yu, Si Shi
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 3911-3923 (2022)
Increasing evidence has confirmed that cancer-associated fibroblasts (CAFs) recruit and induce regulatory T cells (Tregs) and macrophages but inhibit cytotoxic T lymphocyte infiltration to a certain extent, indicating that CAFs have a significant inf
Externí odkaz:
https://doaj.org/article/5a10d4c3a0de4b248d8e82665935c7b8
Autor:
Xiaomeng Liu, Jiang Liu, Jin Xu, Bo Zhang, Miaoyan Wei, Jialin Li, Hang Xu, Xianjun Yu, Wei Wang, Si Shi
Publikováno v:
Translational Oncology, Vol 27, Iss , Pp 101561- (2023)
Pancreatic ductal adenocarcinoma (PDAC) is a highly fatal malignancy that is characterized by an immunosuppressive microenvironment. The immune suppression in PDAC is largely driven by heterogeneous stromal and tumor cells. However, how adipocyte in
Externí odkaz:
https://doaj.org/article/80fe6fb9244b4dd4892bdf5541d7c852
Autor:
Jia Dong, Jiang Liu, Bo Zhang, Chen Liang, Jie Hua, Qingcai Meng, Miaoyan Wei, Wei Wang, Xianjun Yu, Jin Xu
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3270 (2023)
(1) Background: Pancreatic cancer (PC) is one of the most lethal tumors. Mitochondrial dysfunction has been reported to be involved in cancer development; however, its role in PC has remained unclear. (2) Methods: The differentially expressed NMGs we
Externí odkaz:
https://doaj.org/article/bb51d821f2534b3995f0152d8b5cdacb
Autor:
Heng Zhu, Miaoyan Wei, Jin Xu, Jie Hua, Chen Liang, Qingcai Meng, Yiyin Zhang, Jiang Liu, Bo Zhang, Xianjun Yu, Si Shi
Publikováno v:
Molecular Cancer, Vol 19, Iss 1, Pp 1-15 (2020)
Abstract Pancreatic cancer is a highly lethal disease with a poor prognosis, and existing therapies offer only limited effectiveness. Mutation gene sequencing has shown several gene associations that may account for its carcinogenesis, revealing a pr
Externí odkaz:
https://doaj.org/article/a36f2a674c4c420e9fbf056ab660d4ba
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
objectiveDespite the heterogeneous biology of pancreatic cancer, similar surveillance schemas have been used. Identifying the high recurrence risk population and conducting prompt intervention may improve prognosis and prolong overall survival.Method
Externí odkaz:
https://doaj.org/article/cfd41f1222ce463eac966473e0c650d9
Autor:
Yiyin Zhang, Jin Xu, Jie Hua, Jiang Liu, Chen Liang, Qingcai Meng, Miaoyan Wei, Bo Zhang, Xianjun Yu, Si Shi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Background Programmed cell death protein 1 (PD-1) is a key immune checkpoint that regulates peripheral tolerance and protects against autoimmunity. Programmed death ligand-2 (PD-L2) is a less studied ligand to PD-1 and has yet to be fully ex
Externí odkaz:
https://doaj.org/article/5755201821ab499b9ac483a091ca0241
Autor:
Miaoyan Wei, Jin Xu, Jie Hua, Qingcai Meng, Chen Liang, Jiang Liu, Bo Zhang, Wei Wang, Xianjun Yu, Si Shi
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
ObjectiveImmune infiltration plays an important role in tumor development and progression and shows promising prognostic value in numerous tumors. In this study, we aimed to identify the role of immune infiltration in pancreatic neuroendocrine tumors
Externí odkaz:
https://doaj.org/article/b9b0bf80296e45ec818aace6ff10f5e9