Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Miaoqin She"'
Autor:
Lei Xiang, Yanfeng Lou, Lingyu Liu, Yuanling Liu, Weizheng Zhang, Jianxin Deng, Yubin Guan, Miaoqin She, Xinchao You, Minqi Liu, Hongwei Li, Xiaosong Xu, Fang Liu, Xiangsheng Cai
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Increasing evidence suggests that features of the gut microbiota correlate with ischemic stroke. However, the specific characteristics of the gut microbiota in patients suffering different types of ischemic stroke, or recovering from such strokes, ha
Externí odkaz:
https://doaj.org/article/0e74c36623e54d42bec63ec6e4652331
Autor:
John J. Talley, Jingfang Xiong, He Chuang, Wang Yican, Zhengchao Tu, Micky D. Tortorella, Miaoqin She, Minke Li, Yanmei Zhang, Yongzhi Lu, Xiao-Chu Qin, Qiong Pan, Tingting Chen, Xiaorong Liu
Publikováno v:
Journal of medicinal chemistry. 60(10)
In this report, we disclose the design and synthesis of a series of pentafluorosulfanyl (SF5) benzopyran derivatives as novel COX-2 inhibitors with improved pharmacokinetic and pharmacodynamic properties. The pentafluorosulfanyl compounds showed both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b520051764e992d89adfda93ea005810
https://pubmed.ncbi.nlm.nih.gov/28475316
https://pubmed.ncbi.nlm.nih.gov/28475316
Autor:
Xiaoyun Lu, Xiaofen Pan, Zhengchao Tu, Huoyou Long, Fang Leng, Liu Jianqi, Xiaoxi Zhuang, Yupeng Li, Zhang Zhang, Jingxuan Pan, Ke Ding, Yang Bai, Jinfeng Luo, Xingfen Lang, Donghai Wen, Deping Wang, Yubing Feng, Xiaomei Ren, Fengxiang Zhang, Miaoqin She
Publikováno v:
Journal of Medicinal Chemistry. 56:879-894
Bcr-Abl(T315I) mutation-induced imatinib resistance remains a major challenge for clinical management of chronic myelogenous leukemia (CML). Herein, we report GZD824 (10a) as a novel orally bioavailable inhibitor against a broad spectrum of Bcr-Abl m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b80da9b3c56314c99ff46710c7674692
https://doi.org/10.1021/jm301581y
https://doi.org/10.1021/jm301581y
Publikováno v:
Journal of enzyme inhibition and medicinal chemistry. 26(3)
Human uridine-5'-diphosphoglucuronosyltransferases (UGTs) are the major phase II metabolizing enzymes. In the present study, five human UGTs (UGT1A1, 1A4, 1A6, 2B7, and 2B10) were individually expressed and used to examine the inhibition IC(50) value
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef6b8eb3ad59b3e4a54aecdfbd4b768f
https://pubmed.ncbi.nlm.nih.gov/20939765
https://pubmed.ncbi.nlm.nih.gov/20939765
Autor:
Yanmei Zhang, Yican Wang, Chuang He, Xiaorong Liu, Yongzhi Lu, Tingting Chen, Qiong Pan, Jingfang Xiong, Miaoqin She, Zhengchao Tu, Xiaochu Qin, Minke Li, Tortorella, Micky D., Talley, John J.
Publikováno v:
Journal of Medicinal Chemistry; 5/25/2017, Vol. 60 Issue 10, p4135-4146, 12p