Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Miaoge Xue"'
Autor:
Miaoge Xue, Yuexiu Zhang, Haitao Wang, Elizabeth L Kairis, Mijia Lu, Sadeem Ahmad, Zayed Attia, Olivia Harder, Zijie Zhang, Jiangbo Wei, Phylip Chen, Youling Gao, Mark E Peeples, Amit Sharma, Prosper Boyaka, Chuan He, Sun Hur, Stefan Niewiesk, Jianrong Li
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1010142 (2021)
Human respiratory syncytial virus (RSV) is the leading cause of respiratory tract infections in humans. A well-known challenge in the development of a live attenuated RSV vaccine is that interferon (IFN)-mediated antiviral responses are strongly supp
Externí odkaz:
https://doaj.org/article/b173c27ab4264a278cb1cb7a1cbacf70
Autor:
Miaoge Xue, Boxuan Simen Zhao, Zijie Zhang, Mijia Lu, Olivia Harder, Phylip Chen, Zhike Lu, Anzhong Li, Yuanmei Ma, Yunsheng Xu, Xueya Liang, Jiyong Zhou, Stefan Niewiesk, Mark E. Peeples, Chuan He, Jianrong Li
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Here, Xue et al. identify N 6-methyladenosine (m6A) modification sites in RNAs of respiratory syncytial virus (RSV) and show that these sites, particularly sites in the transcript encoding for the viral glycoprotein, affect virus replication in prima
Externí odkaz:
https://doaj.org/article/ae5353928f864471a17a92fe4c1248b7
Autor:
Anzhong Li, Jingyou Yu, Mijia Lu, Yuanmei Ma, Zayed Attia, Chao Shan, Miaoge Xue, Xueya Liang, Kelsey Craig, Nirajkumar Makadiya, Jennifer J. He, Ryan Jennings, Pei-Yong Shi, Mark E. Peeples, Shan-Lu Liu, Prosper N. Boyaka, Jianrong Li
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Current Zika virus (ZIKV) subunit vaccine development largely focuses on prM and E proteins, and the role of NS1 for immune response and protection is unclear. Here, Li et al. develop an attenuated VSV-based vaccine expressing a ZIKV prM-E-NS1 polypr
Externí odkaz:
https://doaj.org/article/8dda5bf46f8146d19d1bf7be27066060
Autor:
Kelsey Craig, Xianjun Dai, Anzhong Li, Mijia Lu, Miaoge Xue, Lucia Rosas, Thomas Z. Gao, Andrew Niehaus, Ryan Jennings, Jianrong Li
Publikováno v:
Viruses, Vol 11, Iss 3, p 213 (2019)
Human noroviruses (HuNoVs) are responsible for more than 95% of the non-bacterial acute gastroenteritis epidemics in the world. The CDC estimates that every year 21 million individuals suffer from HuNoV-induced gastroenteritis in the United States. C
Externí odkaz:
https://doaj.org/article/985af390ea8945028927488c5db11033
Autor:
Yunsheng Xu, Chuan He, Mark E. Peeples, Olivia Harder, Xueya Liang, Boxuan Simen Zhao, Jianrong Li, Zongdi Feng, Miaoge Xue, Jiyong Zhou, Mijia Lu, Thomas Z. Gao, Zijie Zhang, Stefan Niewiesk, Anzhong Li
Publikováno v:
Nature Microbiology. 5:584-598
Internal N6-methyladenosine (m6A) modification is one of the most common and abundant modifications of RNA. However, the biological roles of viral RNA m6A remain elusive. Here, using human metapneumovirus (HMPV) as a model, we demonstrate that m6A se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90a175d9a1d676a710a0aa97f28ece31
https://doi.org/10.1038/s41564-019-0653-9
https://doi.org/10.1038/s41564-019-0653-9
Autor:
Qinzhe Liu, Jiangbo Wei, Sadeem Ahmad, Mark E. Peeples, Amit Sharma, Jianrong Li, Elizabeth L. Kairis, Chuan He, Youling Gao, Dominique Garcin, Sun Hur, Mijia Lu, Miaoge Xue, Yuexiu Zhang, Hai-Tao Wang, Zijie Zhang
Publikováno v:
J Virol
N(6)-Methyladenosine (m(6)A) is the most abundant internal RNA modification catalyzed by host RNA methyltransferases. As obligate intracellular parasites, many viruses acquire m(6)A methylation in their RNAs. However, the biological functions of vira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4277b6116ba87e52e2607f849e50b16
https://europepmc.org/articles/PMC8104112/
https://europepmc.org/articles/PMC8104112/
Autor:
Krista M. D. La Perle, Ryan N. Jennings, Stefan Niewiesk, Jianrong Li, Anzhong Li, Miaoge Xue, Rongzhang Wang, Phylip Chen, Xueya Liang, Mark E. Peeples, Hui Cai, Mijia Lu, Olivia Harder
Publikováno v:
J Virol
Human respiratory syncytial virus (RSV) is the leading viral cause of lower respiratory tract disease in infants and children worldwide. Currently, there are no FDA-approved vaccines to combat this virus. The large (L) polymerase protein of RSV repli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef52bc0e5dfe06e9efccf82e3c4e1417
https://doi.org/10.1128/jvi.01831-20
https://doi.org/10.1128/jvi.01831-20
Autor:
Zayed Attia, Mark E. Peeples, Anzhong Li, Pei Yong Shi, Xueya Liang, Jingyou Yu, Mijia Lu, Shan-Lu Liu, Thomas Z. Gao, Miaoge Xue, Chao Shan, Jianrong Li, Prosper N. Boyaka
Publikováno v:
J Virol
The nonstructural protein 1 (NS1) of several flaviviruses, including West Nile, dengue, and yellow fever viruses, is capable of inducing variable degrees of protection against flavivirus infection in animal models. However, the immunogenicity of NS1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c749646053476d09dde87ccbe8573978
https://doi.org/10.1128/jvi.00048-20
https://doi.org/10.1128/jvi.00048-20
Autor:
Asuncion Mejias, Michael N. Teng, Christopher J. Walker, Mark E. Peeples, Miaoge Xue, Rongzhang Wang, Phylip Chen, Jianrong Li, Olivia Harder, Octavio Ramilo, Stefan Niewiesk, Tiffany L. Jenkins, Jacqueline Corry
Publikováno v:
J Virol
Respiratory syncytial virus (RSV) is the leading cause of acute lower respiratory tract infections in children of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37268a5394370c821b0f0d134e997084
https://pubmed.ncbi.nlm.nih.gov/33177201
https://pubmed.ncbi.nlm.nih.gov/33177201
Autor:
Mark E. Peeples, Jianrong Li, Prosper N. Boyaka, Ryan N. Jennings, Jingyou Yu, Miaoge Xue, Yuanmei Ma, Zayed Attia, Pei Yong Shi, Mijia Lu, Anzhong Li, Xueya Liang, Nirajkumar Makadiya, Chao Shan, Kelsey Craig, Shan-Lu Liu, Jennifer J. He
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature Communications
Nature Communications
Current efforts to develop Zika virus (ZIKV) subunit vaccines have been focused on pre-membrane (prM) and envelope (E) proteins, but the role of NS1 in ZIKV-specific immune response and protection is poorly understood. Here, we develop an attenuated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf1e592ef1b6aff081bfcab98d3d36f2
https://doaj.org/article/8dda5bf46f8146d19d1bf7be27066060
https://doaj.org/article/8dda5bf46f8146d19d1bf7be27066060