Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Miao-xing Wang"'
Autor:
Eri Ohta, Masanori Itoh, Masashi Ueda, Yoko Hida, Miao-Xing Wang, Miki Hayakawa-Ogura, Shimo Li, Emika Nishida, Kazunori Ohta, Tana, Saiful Islam, Kiyomi Nakagawa, Tomomi Sunayama, Huayue Chen, So Hirata, Masashi Endo, Yoya Ohno, Toshiyuki Nakagawa
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219782 (2019)
Apoptotic protease-activating factor 1 (Apaf-1) is a component of apoptosome, which regulates caspase-9 activity. In addition to apoptosis, Apaf-1 plays critical roles in the intra-S-phase checkpoint; therefore, impaired expression of Apaf-1 has been
Externí odkaz:
https://doaj.org/article/5eb083a2c86b476d9a93a91c7bdcf482
Autor:
Emika Nishida, Dong-soo Lee, Saiful Islam, Miao-xing Wang, Toshiyuki Nakagawa, Masanori Itoh, Masatake Osawa, Masashi Ueda, Tana, Kiyomi Nakagawa
Publikováno v:
Brain Research. 1688:81-90
Olfaxin, which is a BNIP2 and Cdc42GAP homology (BCH) domain-containing protein, is predominantly expressed in mitral and tufted (M/T) cells in the olfactory bulb (OB). Olfaxin and Caytaxin, which share 56.3% amino acid identity, are similar in their
Autor:
Toshiyuki Nakagawa, Tomomi Sunayama, Emika Nishida, Shimo Li, Masashi Endo, Saiful Islam, Huayue Chen, Kazunori Ohta, Eri Ohta, So Hirata, Miao-xing Wang, Miki Hayakawa-Ogura, Masanori Itoh, Yoko Hida, Masashi Ueda, Kiyomi Nakagawa, Tana, Yoya Ohno
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 7, p e0219782 (2019)
PLoS ONE, Vol 14, Iss 7, p e0219782 (2019)
Apoptotic protease-activating factor 1 (Apaf-1) is a component of apoptosome, which regulates caspase-9 activity. In addition to apoptosis, Apaf-1 plays critical roles in the intra-S-phase checkpoint; therefore, impaired expression of Apaf-1 has been
Autor:
Shimo Li, Emika Nishida, Masashi Ueda, Hiroshi Akanabe, Saiful Islam, Kiyomi Nakagawa, Daisuke Yanagida, Takato Muro, Miki Hayakawa, Ryo Nakabayashi, Takashi Inuzuka, Yoshinori Itoh, Kazunori Ohta, Kazuki Saito, Tetsuya Mori, Tokio Chikaishi, Masanori T. Itoh, Kaori Ohzawa, Tana, Chihiro Suzuki, Yasushi Yamada, Masuko Kobori, Miao-xing Wang, Toshiyuki Nakagawa, Yuichi Hayashi
Publikováno v:
SC30201706210018
Patients with Alzheimer's disease (AD) experience a wide array of cognitive deficits, which typically include the impairment of explicit memory. In previous studies, the authors reported that a flavonoid, quercetin, reduces the expression of ATF4 and
Autor:
Saiful Islam, Huayue Chen, Kiyomi Nakagawa, Toshiyuki Nakagawa, Shimo Li, Tana, Masanori Itoh, Miao-xing Wang, Masashi Ueda, Miki Hayakawa
Publikováno v:
Biochemical and biophysical research communications. 474(2)
The endoplasmic reticulum (ER) is important in various cellular functions, such as secretary and membrane protein biosynthesis, lipid synthesis, and calcium storage. ER stress, including membrane distortion, is associated with many diseases such as H
Autor:
Yoko Hida, Tana, Masashi Ueda, Emika Nishida, Kazunori Ohta, Masanori Itoh, Toshiyuki Nakagawa, Saiful Islam, Shimo Li, Miki Hayakawa, Miao-xing Wang
Publikováno v:
Biochemical and biophysical research communications. 470(1)
Cell death abnormal (ced)-3 and ced-4 genes regulate apoptosis to maintain tissue homeostasis in Caenorhabditis elegans. Apoptosome formation and CED-4 translocation drive CED-3 activation. However, the precise role of CED-4 translocation is not yet
Autor:
Miki Hayakawa, Toshiyuki Nakagawa, Kazunori Ohta, Shimo Li, Ryoko Hasebe-Matsubara, Miao-xing Wang, Masashi Ueda, Eri Ohta, Huayue Chen, Akihito Mizuno, Yoko Hida, Masanori Itoh, Munekazu Matsumoto, Yoshika Hayakawa-Yano
Publikováno v:
Biochemical and biophysical research communications. 443(4)
The endoplasmic reticulum (ER) plays a pivotal role in cellular functions such as the ER stress response. However, the effect of the ER membrane on caspase activation remains unclear. This study reveals that polyglutamine oligomers augmented at ER in
Autor:
Kazunori Ohta, Kaori Ohzawa, Saiful Islam, Masuko Kobori, Miao-xing Wang, Takashi Inuzuka, Emika Nishida, Toshiyuki Nakagawa, Miki Hayakawa, Masashi Ueda, Chihiro Suzuki, Shimo Li, Masanori Itoh
Publikováno v:
Neurobiology of aging. 36(9)
The production of amyloid β (Aβ) in the brain from Aβ precursor protein (APP) through γ-secretase is important for the pathogenesis of Alzheimer's disease (AD). Our previous studies have demonstrated that autophagy impairment and endoplasmic reti
Autor:
Eri Ohta, Shimo Li, Yoko Hida, Akihito Mizuno, Kazunori Ohta, Masanori Itoh, Miao-xing Wang, Masashi Ueda, Yoshihiro Suzuki, Yoshika Hayakawa-Yano, Toshiyuki Nakagawa
Publikováno v:
Brain research. 1488
Prune homolog 2 (Drosophila) (PRUNE2) encodes a BCH motif-containing protein that shares homology with the Cayman ataxia-related protein Caytaxin. Caytaxin is a substrate of caspase-3 and is specifically expressed at the presynapse of vesicular-type
Autor:
Takashi Inuzuka, Yoko Hida, Eri Ohta, Mitsuaki Sobajima, Yukihiro Tsuzuki, Manabu Furoi, Toshiyuki Nakagawa, Masanori Itoh, Masashi Ueda, Tatsuya Fukushima, Akihito Mizuno, Shimo Li, Kazunori Ohta, Yoshimasa Bohmoto, Masuko Kobori, Miao-xing Wang
Publikováno v:
Biochemical and biophysical research communications. 416(3-4)
The endoplasmic reticulum (ER) copes with unfolded proteins in the lumen (ER stress) by activating three distinct intracellular signaling pathways of unfolded protein response (UPR). ER stress contributes to the pathogenesis of obesity and diabetes,