Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Miao-jin Ji"'
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Both pain and psychiatric disorders, such as anxiety and depression, significantly impact quality of life for the sufferer. The two also share a strong pathological link: chronic pain-induced negative affect drives vulnerability to psychiatric disord
Externí odkaz:
https://doaj.org/article/d514701bdcbc41caaac3705d980af593
Autor:
Miao‐Jin Ji, Zhi‐Qiang Gao, Jiao Yang, Ji‐Heng Cai, Ke‐Xue Li, Jie Wang, Hongxing Zhang, Cheng‐Hua Zhou, Jun‐Li Cao, Chao Liu
Publikováno v:
Acta Physiologica. 236
Endogenous dynorphin signaling via kappa opioid receptors (KORs) plays a key role in producing the depressive and aversive consequences of stress. We investigated the behavioral effects of the dynorphin/KOR system in the ventral pallidum (VP) and stu
Publikováno v:
Journal of visualized experiments : JoVE. (170)
Alzheimer's disease (AD) is a neurodegenerative disease that contributes to 60-70% dementia around the world. One of the hallmarks of AD undoubtedly lies on accumulation of amyloid-β (Aβ) in the brain. Aβ is produced from the proteolytic cleavage
Publikováno v:
Journal of Visualized Experiments.
Alzheimer's disease (AD) is a neurodegenerative disease that contributes to 60-70% dementia around the world. One of the hallmarks of AD undoubtedly lies on accumulation of amyloid-β (Aβ) in the brain. Aβ is produced from the proteolytic cleavage
Publikováno v:
Gene. 780
As one of the most common complications of diabetes, nephropathy develops in approximately 40% of diabetic individuals. Although end stage kidney disease is known as one of the most consequences of diabetic nephropathy, the majority of diabetic indiv
Autor:
Zi Chen, Jian-Jun Wang, Xiao-Yang Zhang, Jing-Ning Zhu, Lei Yu, Xiao-Chun Peng, Miao-Jin Ji, Yang-Xun Zhang
Publikováno v:
Neuroscience bulletin. 34(6)
The ventral pallidum (VP) is a crucial component of the limbic loop of the basal ganglia and participates in the regulation of reward, motivation, and emotion. Although the VP receives afferent inputs from the central histaminergic system, little is
Publikováno v:
Molecular Psychiatry
Hypothalamic neuropeptide orexin has been implicated in the pathophysiology of psychiatric disorders and accumulating clinical evidence indicates a potential link between orexin and depression. However, the exact role of orexin in depression, particu
Publikováno v:
Molecular Psychiatry. 24:161-161
Autor:
Hao Hong, Yan Long, Miao-jin Ji, Yong-Qi Li, Ming-xing Miao, Ning Li, Hui Ji, Su-Su Tang, Lan Chen, Jia-chang Li, Xijing Chen, Mei Hu
Publikováno v:
The International Journal of Neuropsychopharmacology. 17:581-592
Deposition of extracellular amyloid-β (Aβ) peptide is one of the pathological hallmarks of Alzheimer's disease (AD). Accumulation of Aβ is thought to associate with cognition deficits, neuroinflammation and apoptosis observed in AD. However, effec
Autor:
Yan Long, Zhen-lin Mei, Yun-Qi An, Hong-Bin Sun, Miao-jin Ji, Ling-yi Kong, Su-Su Tang, Hao Hong, Ming-xing Miao, Mei Hu, Qing-Hua Hu, Xu-Ben Yu
Publikováno v:
International Journal of Neuropsychopharmacology
Background: Emerging data have demonstrated that peroxisome proliferator-activated receptor δ (PPARδ) activation confers a potentially neuroprotective role in some neurodegenerative diseases. However, whether PPARδ is involved in depression is unk