Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Mian M. Alauddin"'
Publikováno v:
Molecular Imaging, Vol 3 (2004)
2′-Deoxy-2′-fluoro-5-methyl-1-β- d -arabinofuranosyluracil (FMAU), 9-(4-fluoro-3-hydroxy-methyl-butyl)guanine (FHBG) and 9-[(3-fluoro-1-hydroxy-2-propoxy)methyl]-guanine (FHPG) have been evaluated in a human breast cancer model as potential radi
Externí odkaz:
https://doaj.org/article/81253112c0bc41c19e9b40986951761e
Publikováno v:
Molecular Imaging, Vol 1 (2002)
2′-Deoxy-2′-flouro-5-methyl-1-β- d -arabinofuranosyluracil (FMAU) has been evaluated in HT-29 cells as a potential positron emission tomography (PET) radiotracer for imaging HSV-tk gene expression in vivo. In vitro experiments demonstrate that t
Externí odkaz:
https://doaj.org/article/f255ad84326c4aa59ecc9c8ef9d97501
Autor:
Leslie A. Khawli, Mian M. Alauddin
Publikováno v:
Current Medicinal Chemistry. 28:647-672
Background: Monoclonal antibodies (mAbs) against tumor-associated antigens have been shown to target tumors with specificity and selectivity; therefore, it was hypothesized that cancer could be treated with mAbs without side effects. In the early 198
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c17870c249e74f53e66663221b7e8db
https://doi.org/10.2174/0929867327666200128102958
https://doi.org/10.2174/0929867327666200128102958
Autor:
Robin Bonomi, Uday Mukhopadhyay, Aleksandr Shavrin, Hsien-Hsien Yeh, Anjoy Majhi, Sajeewa W Dewage, Amer Najjar, Xin Lu, G Andrés Cisneros, William P Tong, Mian M Alauddin, Ren-Shuan Liu, Thomas J Mangner, Nashaat Turkman, Juri G Gelovani
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0133512 (2015)
Histone deacetylases (HDAC's) became increasingly important targets for therapy of various diseases, resulting in a pressing need to develop HDAC class- and isoform-selective inhibitors. Class IIa deacetylases possess only minimal deacetylase activit
Externí odkaz:
https://doaj.org/article/3ab80ca33b63401587d670592377c586
Autor:
Mian M. Alauddin
Publikováno v:
Current Medicinal Chemistry. 25:1867-1878
Background: Developed as an antiviral drug in the 1960s and 1970s, the thymidine analogue 2′-deoxy-2′-fluoro-5-methyl-1-β-D-arabinofuranosyluracil (FMAU) was translated to clinical application for treatment of herpes simplex virus infection. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc927bf5118ca6fb5dbf70ecfb67ac2c
https://doi.org/10.2174/0929867325666171129125217
https://doi.org/10.2174/0929867325666171129125217
Autor:
Juri G. Gelovani, Jeffrey Rogers, Patrick J. Gillespie, Wadih Arap, Carlos J. Perez, Lawrence E. Williams, Richard A. Gibbs, David W. Brammer, Mian M. Alauddin, Christian R. Abee, Renata Pasqualini, Kirstin F. Barnhart, Fernando Benavides, Mihai Gagea, Manoop S. Bhutani, Daniel Young, Russell Broaddus, Bruce J. Bernacky, Richard L. Sidman, Muthuswamy Raveendran, Mei Tian
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The discovery of MLH1-rheMac hereditary nonpolyposis colorectal cancer syndrome in rhesus macaques (MLH1-rheMac HNPCC), which is an orthologue of Lynch syndrome in humans, is highly significant in the field of oncology. The hereditary na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65d8f3380f41f174868e404bf55296b9
http://europepmc.org/articles/PMC5856559
http://europepmc.org/articles/PMC5856559
Autor:
Emerson C Perin, Mei Tian, Frank C Marini, Guilherme V Silva, Yi Zheng, Fred Baimbridge, Xin Quan, Marlos R Fernandes, Amir Gahremanpour, Daniel Young, Vincenzo Paolillo, Uday Mukhopadhyay, Agatha T Borne, Rajesh Uthamanthil, David Brammer, James Jackson, William K Decker, Amer M Najjar, Michael W Thomas, Andrei Volgin, Brian Rabinovich, Suren Soghomonyan, Hwan-Jeong Jeong, Jesse M Rios, David Steiner, Simon Robinson, Osama Mawlawi, Tinsu Pan, Jason Stafford, Vikas Kundra, Chun Li, Mian M Alauddin, James T Willerson, Elizabeth Shpall, Juri G Gelovani
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e22949 (2011)
The long-term fate of stem cells after intramyocardial delivery is unknown. We used noninvasive, repetitive PET/CT imaging with [(18)F]FEAU to monitor the long-term (up to 5 months) spatial-temporal dynamics of MSCs retrovirally transduced with the s
Externí odkaz:
https://doaj.org/article/197618fa7aab459d973c22629837dcd5
Autor:
Leo Garcia Flores, Susanna Bertolini, Hsin Hsin Yeh, Daniel Young, Uday Mukhopadhyay, Ashutosh Pal, Yunming Ying, Andrei Volgin, Aleksandr Shavrin, Suren Soghomonyan, William Tong, William Bornmann, Mian M Alauddin, Craig Logsdon, Juri G Gelovani
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7977 (2009)
Early diagnosis of pancreatic carcinoma with highly sensitive diagnostic imaging methods could save lives of many thousands of patients, because early detection increases resectability and survival rates. Current non-invasive diagnostic imaging techn
Externí odkaz:
https://doaj.org/article/d6f39e3536d94754b1a9ab1ec8c9eb87
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 59:103-108
Anaplastic lymphoma kinase (ALK), an oncogenic receptor tyrosine kinase, has emerged as a therapeutic target in solid and hematologic tumors. Although several ALK inhibitors have gained recent approval for therapy, non-invasive indicators of target e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cba08b73c4416b5f4df9d84368cf216e
https://doi.org/10.1002/jlcr.3373
https://doi.org/10.1002/jlcr.3373
Autor:
Mian M. Alauddin, Louis De Palatis
Publikováno v:
Current Medicinal Chemistry. 22:3370-3389
Early detection of pancreatic cancer has been a long-standing challenge in determining prognosis and management of the deadly disease. Although the incidence of pancreatic cancer is low (2% of all malignancies), it is the fourth leading cause of deat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8342caa78f8ef43f6df0cc8b8e41b66a
https://doi.org/10.2174/0929867322666150821094015
https://doi.org/10.2174/0929867322666150821094015