Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Miaki Uzu"'
Autor:
Kanako Miyano, Katsuya Ohbuchi, Yuka Sudo, Kouichiro Minami, Toru Yokoyama, Masahiro Yamamoto, Miaki Uzu, Miki Nonaka, Seiji Shiraishi, Hiroaki Murata, Yoshikazu Higami, Yasuhito Uezono
Publikováno v:
Journal of Pharmacological Sciences, Vol 143, Iss 4, Pp 320-324 (2020)
Cellular dielectric spectroscopy (CDS) is a novel technology enabling pharmacological evaluation of multiple receptor types with a label-free cell-based assay. We evaluated activities of a family of ligand-gated channels, transient receptor potential
Externí odkaz:
https://doaj.org/article/c353329a3d5446a2926a09e994c6518d
Autor:
Kanako Miyano, Seiya Hasegawa, Noriho Asai, Miaki Uzu, Wakako Yatsuoka, Takao Ueno, Miki Nonaka, Hideaki Fujii, Yasuhito Uezono
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Several clinical studies have reported that Japanese herbal medicine Hangeshashinto (HST) has beneficial effects on chemotherapy-induced oral ulcerative mucositis (OUM). Our previous research demonstrated that HST improves chemotherapy-induced OUM th
Externí odkaz:
https://doaj.org/article/6d4ab785a8704253be199f77913126c5
Autor:
Kanako Miyano, Minori Ikehata, Kaori Ohshima, Yuki Yoshida, Yasuhiro Nose, Sei-ichi Yoshihara, Katsuyuki Oki, Seiji Shiraishi, Miaki Uzu, Miki Nonaka, Yoshikazu Higami, Yasuhito Uezono
Publikováno v:
PLoS ONE, Vol 17, Iss 2 (2022)
Mesenchymal stem cells (MSCs), which are isolated from adipose tissue (AD-MSCs), umbilical cord (UC-MSCs), or bone marrow, have therapeutic potential including anti-inflammatory and immunomodulatory activities. It was recently reported that MSCs are
Externí odkaz:
https://doaj.org/article/d3c62824590b4058be9be33347c89cb9
Autor:
Sei Manabe, Kanako Miyano, Yuriko Fujii, Kaori Ohshima, Yuki Yoshida, Miki Nonaka, Miaki Uzu, Yoshikazu Matsuoka, Tetsufumi Sato, Yasuhito Uezono, Hiroshi Morimatsu
Publikováno v:
Journal of Pharmacological Sciences, Vol 140, Iss 2, Pp 171-177 (2019)
Morphine, fentanyl, and oxycodone are widely used as analgesics, and recently hydromorphone has been approved in Japan. Although all of these are selective for μ-opioid receptors (MORs) and have similar structures, their analgesic potencies and adve
Externí odkaz:
https://doaj.org/article/6b1b30198a8c4e6e9523646327cf78ee
Autor:
Miaki Uzu, Miki Nonaka, Kanako Miyano, Hiromi Sato, Nagomi Kurebayashi, Kazuyoshi Yanagihara, Takashi Sakurai, Akihiro Hisaka, Yasuhito Uezono
Publikováno v:
Journal of Pharmacological Sciences, Vol 140, Iss 1, Pp 109-112 (2019)
Cancer cachexia is a systemic wasting syndrome characterized by anorexia and loss of body weight. The xanthine oxidase (XO) inhibitor febuxostat is one of the promising candidates for cancer cachexia treatment. However, cachexic symptoms were not all
Externí odkaz:
https://doaj.org/article/328c70525a314051acf5569e9dec61f5
Publikováno v:
Journal of Pharmacological Sciences, Vol 134, Iss 2, Pp 101-107 (2017)
The constituent protein of gap junctions, connexin (Cx), interacts with various proteins via its C-terminus region, including kinases, cell-adhesion proteins, and a pro-apoptotic protein, Bax. This molecular interaction may affect expression and func
Externí odkaz:
https://doaj.org/article/83463ae9c9ed4172912ede57779ae1ee
Publikováno v:
Frontiers in Nutrition, Vol 5 (2018)
Herbal medicines are currently employed for the treatment of several types of diseases, and also employed for the improvement of Quality of Life (QOL) of patients over the world, in particular, in Asian countries. In Japan, a Japanese herbal medicine
Externí odkaz:
https://doaj.org/article/20b3faa070c243538de28def4eadb1ed
Effect of enhanced expression of connexin 43 on sunitinib-induced cytotoxicity in mesothelioma cells
Autor:
Miaki Uzu, Hiromi Sato, Ryota Yamada, Tatsuro Kashiba, Yukihiro Shibata, Katsunori Yamaura, Koichi Ueno
Publikováno v:
Journal of Pharmacological Sciences, Vol 128, Iss 1, Pp 17-26 (2015)
Connexin (Cx) makes up a type of intercellular channel called gap junction (GJ). GJ plays a regulatory role in cellular physiology. The Cx expression level is often decreased in cancer cells compared to that in healthy ones, and the restoration of it
Externí odkaz:
https://doaj.org/article/3242a270ce7447608dadcecc71eac92c
Autor:
Toshiaki Takezawa1, Miaki Uzu1
Publikováno v:
Journal of Toxicological Sciences. Jan2022, Vol. 47 Issue 1, p39-50. 12p.
Autor:
Katsuya Ohbuchi, Miaki Uzu, Kouichiro Minami, Seiji Shiraishi, Yasuhito Uezono, Toru Yokoyama, Masahiro Yamamoto, Hiroaki Murata, Yoshikazu Higami, Miki Nonaka, Yuka Sudo, Kanako Miyano
Publikováno v:
Journal of Pharmacological Sciences, Vol 143, Iss 4, Pp 320-324 (2020)
Cellular dielectric spectroscopy (CDS) is a novel technology enabling pharmacological evaluation of multiple receptor types with a label-free cell-based assay. We evaluated activities of a family of ligand-gated channels, transient receptor potential