Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Mia M. Thi"'
Autor:
Antonio Cibelli, Sandra Veronica Lopez-Quintero, Sean Mccutcheon, Eliana Scemes, David C. Spray, Randy F. Stout, Sylvia O. Suadicani, Mia M. Thi, Marcia Urban-Maldonado
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
We transduced mouse cortical astrocytes cultured from four litters of embryonic wildtype (WT) and connexin43 (Cx43) null mouse pups with lentiviral vector encoding hTERT and measured expression of astrocyte-specific markers up to passage 10 (p10). Th
Externí odkaz:
https://doaj.org/article/8040b483b6574b3d9e818fbff5a9e81b
Autor:
Mitchell B. Schaffler, Mia M. Thi, David C. Spray, Macy Castaneda, James F. Boorman-Padgett, Karl J. Lewis
Publikováno v:
Journal of Visualized Experiments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c50a5d6e03a2936a204c31390247fde3
https://doi.org/10.3791/64366
https://doi.org/10.3791/64366
Autor:
Zeynep Seref-Ferlengez, Stephanie Maung, Mitchell B Schaffler, David C Spray, Sylvia O Suadicani, Mia M Thi
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155107 (2016)
Type 1 diabetes (T1D) causes a range of skeletal problems, including reduced bone density and increased risk for bone fractures. However, mechanisms underlying skeletal complications in diabetes are still not well understood. We hypothesize that high
Externí odkaz:
https://doaj.org/article/7b82f99149e44947bd69209a5ef39d5a
Autor:
Hiromitsu Negoro, Marcia Urban-Maldonado, Louis S Liou, David C Spray, Mia M Thi, Sylvia O Suadicani
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e106269 (2014)
Urothelial cells respond to bladder distension with ATP release, and ATP signaling within the bladder and from the bladder to the CNS is essential for proper bladder function. In other cell types, pannexin 1 (Panx1) channels provide a pathway for mec
Externí odkaz:
https://doaj.org/article/012439c26b7845c980a9966e4a151408
Autor:
Mia M. Thi, Karl J. Lewis, Zeynep Seref-Ferlengez, Samuel Stephen, Sheldon Weinbaum, David C. Spray, Joyce Louie, Robert J. Majeska, Pamela Cabahug-Zuckerman, James F. Boorman-Padgett, Mitchell B. Schaffler, Jelena Basta-Pljakic
Publikováno v:
Bone
Microstructural adaptation of bone in response to mechanical stimuli is diminished with estrogen deprivation. Here we tested in vivo whether ovariectomy (OVX) alters the acute response of osteocytes, the principal mechanosensory cells of bone, to mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afdaa1ba18844bc2821f38ef48d3a60a
https://doi.org/10.1016/j.bone.2021.116072
https://doi.org/10.1016/j.bone.2021.116072
Autor:
Sheldon Weinbaum, Dorra Frikha-Benayed, Samuel Stephen, Karl J. Lewis, Mitchell B. Schaffler, Mia M. Thi, Robert J. Majeska, Joyce Louie, Zeynep Seref-Ferlengez, David C. Spray
Publikováno v:
Proceedings of the National Academy of Sciences. 114:11775-11780
Osteocytes are considered to be the major mechanosensory cells of bone, but how osteocytes in vivo process, perceive, and respond to mechanical loading remains poorly understood. Intracellular calcium (Ca2+) signaling resulting from mechanical stimul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5827b43dffa3d49fb8783aa04061b41f
https://doi.org/10.1073/pnas.1707863114
https://doi.org/10.1073/pnas.1707863114
Publikováno v:
J Sex Med
Background Distension of hollow organs is known to release adenosine triphosphate (ATP) from the lining epithelium, which triggers local responses and activates sensory nerves to convey information to the central nervous system. However, little is kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::816279f30cfd705c87ea6282a7f22eb5
https://pubmed.ncbi.nlm.nih.gov/32241676
https://pubmed.ncbi.nlm.nih.gov/32241676
Publikováno v:
Annals of the New York Academy of Sciences. 1383:67-79
This review focuses on bone mechanobiology in type 1 diabetes (T1D), an area of research on diabetes-associated skeletal complications that is still in its infancy. We first provide a brief overview of the deleterious effects of diabetes on the skele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7396692b931ca740010b6c2ae4aa35a3
https://doi.org/10.1111/nyas.13202
https://doi.org/10.1111/nyas.13202
Autor:
Wing-Yee Cheung, J. Christopher Fritton, Zeynep Seref-Ferlengez, Stacy Ann Morgan, Mia M. Thi, Sylvia O. Suadicani, Jelena Basta-Pljakic, Robert J. Majeska, David C. Spray, Mitchell B. Schaffler
Publikováno v:
Journal of Bone and Mineral Research. 31:890-899
Osteocyte apoptosis is required to induce intracortical bone remodeling after microdamage in animal models, but how apoptotic osteocytes signal neighboring "bystander" cells to initiate the remodeling process is unknown. Apoptosis has been shown to o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a016e80440f14dfe1bc45e1cc4d6cfb1
https://doi.org/10.1002/jbmr.2740
https://doi.org/10.1002/jbmr.2740
Autor:
Mia M. Thi, Mary B. Goldring, Lin Xu, Robert J. Majeska, Zhiyong He, Daniel J. Leong, John A. Hardin, Mitchell B. Schaffler, Hui B. Sun, Liu Yang, Neil J. Cobelli
Publikováno v:
Annals of the New York Academy of Sciences. 1442(1)
Osteoarthritis (OA) pathogenesis is mediated largely through the actions of proteolytic enzymes such as matrix metalloproteinase (MMP) 13. The transcriptional regulator CITED2, which suppresses the expression of MMP13 in chondrocytes, is induced by i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03579d5c1dbb0087abaaa97c2cd599d8
https://pubmed.ncbi.nlm.nih.gov/30891766
https://pubmed.ncbi.nlm.nih.gov/30891766