Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mia Jaffe"'
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 1, Pp 143-153 (2017)
Systematic screens for genetic interactions are a cornerstone of both network and systems biology. However, most screens have been limited to characterizing interaction networks in a single environment. Moving beyond this static view of the cell requ
Externí odkaz:
https://doaj.org/article/4ff92dad4c8c4aa98976c6b2e4311313
Autor:
Aaron F. Phillips, Rumin Zhang, Akanksha Verma, Tamar Feinberg, Mia Jaffe, Marysol Chu Carty, Ryan Schulz, Sarah Bettigole, Celia Andreu, Scott Drutman, Michael Su, Derek Cogan, Christina H. Eng
Publikováno v:
Cancer Research. 83:517-517
Chromosome instability (CIN) is an attribute of cancer cells that has yet to be fully exploited therapeutically, despite its prevalence across many tumor types and lack of occurrence in normal cells. To identify genes uniquely essential to CINhigh ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4319c5a8ec94ce0d51a8db093c358eb8
https://doi.org/10.1158/1538-7445.am2023-517
https://doi.org/10.1158/1538-7445.am2023-517
Autor:
Robert P. St.Onge, Gavin Sherlock, Mia Jaffe, Justin D. Smith, Sasha F. Levy, Adam K. Dziulko
Large-scale genetic interaction (GI) screens in yeast have been invaluable for our understanding of molecular systems biology and for characterizing novel gene function. Owing in part to the high costs and long experiment times required, a prepondera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e28fcdcd68250cd600c83b0ffa2b92
https://europepmc.org/articles/PMC6442382/
https://europepmc.org/articles/PMC6442382/
Autor:
James Yan, Alexandra Smith, Kate Fox, Julie K. Allen, Thomas N. Wight, Hao Wei, Inkyung Kang, David A. Dichek, Jie Hong Hu, Stoyan N. Angelov, Liang Du, Nathan Airhart, Rachel Enstrom, Mia Jaffe
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35:2647-2656
Objective— Prenatal deletion of the type II transforming growth factor-β (TGF-β) receptor (TBRII) prevents normal vascular morphogenesis and smooth muscle cell (SMC) differentiation, causing embryonic death. The role of TBRII in adult SMC is less
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f67c0dffbb6ed71423165b22c1acb341
https://doi.org/10.1161/atvbaha.115.306573
https://doi.org/10.1161/atvbaha.115.306573
Autor:
David Clifford, Daniel D. Sprockett, Emily Alsentzer, Kerwyn Casey Huang, Mia Jaffe, Gabriela K. Fragiadakis, Bevan Emma Huang, Evan M. Masutani, Justin L. Sonnenburg, Joshua E. Elias, Joshua S. Lichtman, Elvis Ikwa
Publikováno v:
The ISME Journal. 10:1170-1181
Endogenous intestinal microbiota have wide-ranging and largely uncharacterized effects on host physiology. Here, we used reverse-phase liquid chromatography-coupled tandem mass spectrometry to define the mouse intestinal proteome in the stomach, jeju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed4a3bb1d0bc3b4c524598f2949ac6a7
https://doi.org/10.1038/ismej.2015.187
https://doi.org/10.1038/ismej.2015.187
Autor:
Caroline J. Pennington, Casilde Sesti, Liang Du, April Stempien-Otero, Dylan R. Edwards, Michael R. Preusch, Madeline Nieves-Cintrón, David A. Dichek, Andrew D. Frutkin, Helén L. Dichek, Daniel Minter, Mia Jaffe, Goro Otsuka, Julien C. Marie, Jie Hong Hu
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 29:1251-1257
Objective—Impairment of transforming growth factor (TGF)-β1 signaling accelerates atherosclerosis in experimental mice. However, it is uncertain whether increased TGF-β1 expression would retard atherosclerosis. The role of TGF-β1 in aneurysm for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc87cc5a1138042453a131a3dfad85d
https://doi.org/10.1161/atvbaha.109.186593
https://doi.org/10.1161/atvbaha.109.186593
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35
Objectives: The role of TGF-β signaling in adult vascular homeostasis and aortic aneurysm formation is controversial. Some studies report an association between aneurysm formation and evidence of increased TGF-β signaling in the aortic media; other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::273a1ce6b20e540e05e4803cd19f2896
https://doi.org/10.1161/atvb.35.suppl_1.455
https://doi.org/10.1161/atvb.35.suppl_1.455
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34
Introduction: Prenatal deletion of the type II TGF-beta receptor (TBRII) prevents normal vascular morphogenesis, impairs smooth muscle cell (SMC) differentiation and matrix accumulation, and results in embryonic death in mid-gestation (~embryonic day
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::722fd4282f45deb53c29b9378ce1624a
https://doi.org/10.1161/atvb.34.suppl_1.84
https://doi.org/10.1161/atvb.34.suppl_1.84
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 33
Background The development of mouse lines that drive inducible deletion of conditional alleles specifically in smooth muscle cells (SMC-Cre mice) is a major advance in experimental vascular biology. Two recently reported SMC-Cre lines differ in the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29f288fce361553029cf7ad07826528e
https://doi.org/10.1161/atvb.33.suppl_1.a207
https://doi.org/10.1161/atvb.33.suppl_1.a207
Autor:
Ida M. Washington, Liang Du, Nagadhara Dronadula, Elaine C. Davis, Mia Jaffe, Michael T. Chin, Casilde Sesti, Donna B. Stolz, David A. Dichek
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 32(1)
Objective— Transforming growth factor-β (TGF-β) signaling is required for normal vascular development. We aimed to discover the role of TGF-β signaling in embryonic smooth muscle cells (SMCs). Methods and Results— We bred mice with smooth musc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87e3b78c70da8b5b351467644a3728a2
https://pubmed.ncbi.nlm.nih.gov/21979435
https://pubmed.ncbi.nlm.nih.gov/21979435