Výsledky vyhledávání - "Mia H. E. Kennedy"

Akademický článek

Littermate-Controlled Experiments Reveal Eosinophils Are Not Essential for Maintaining Steady-State IgA and Demonstrate the Influence of Rearing Conditions on Antibody Phenotypes in Eosinophil-Deficient Mice

Autor: Rachael D. FitzPatrick, Mia H. E. Kennedy, Katherine M. Lawrence, Courtney M. Gauthier, Brandon E. Moeller, Andrew N. Robinson, Lisa A. Reynolds

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

Conflicting data has emerged regarding a role for eosinophils in IgA production, with some reports that eosinophils support both secretory and circulating IgA levels during homeostasis. Previous studies have compared antibody levels between wildtype

Externí odkaz: https://doaj.org/article/369d5149df8749fd8cfe6cfcc7558859

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Akademický článek

Impaired host resistance to Salmonella during helminth co-infection is restored by anthelmintic treatment prior to bacterial challenge.

Autor: Tara P Brosschot, Katherine M Lawrence, Brandon E Moeller, Mia H E Kennedy, Rachael D FitzPatrick, Courtney M Gauthier, Dongju Shin, Dominique M Gatti, Kate M E Conway, Lisa A Reynolds

Publikováno v: PLoS Neglected Tropical Diseases, Vol 15, Iss 1, p e0009052 (2021)

Intestinal helminth infection can impair host resistance to co-infection with enteric bacterial pathogens. However, it is not known whether helminth drug-clearance can restore host resistance to bacterial infection. Using a mouse helminth-Salmonella

Externí odkaz: https://doaj.org/article/792b9c9ae60d47849dab72b19f7dd5ba

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MHCII+CD80+ thymic eosinophils increase in abundance during neonatal development in mice and their accumulation is microbiota-dependent

Autor: Dominique M Gatti, Courtney M Gauthier, Brandon E Moeller, Rachael D FitzPatrick, Mia H E Kennedy, Victoria Pluzhnikova, Kate M E Conway, Julian Smazynski, Robert L Chow, Lisa A Reynolds

Publikováno v: Journal of Leukocyte Biology.

Eosinophils are present in the thymus of mammals, yet their function at this site during homeostatic development is unknown. We used flow cytometry to determine the abundance and phenotype of eosinophils (here defined as SSchigh SiglecF+ CD11b+ CD45+

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0916d504eca1147141c410abcf8bbdc9
https://doi.org/10.1093/jleuko/qiad064

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Small Intestinal Levels of the Branched Short-Chain Fatty Acid Isovalerate Are Elevated during Infection with Heligmosomoides polygyrus and Can Promote Helminth Fecundity

Autor: Lisa A. Reynolds, Katherine M Lawrence, Jenna M Lane, Tara P. Brosschot, Mia H E Kennedy, Grace M. Mariene, Rachael D. FitzPatrick, James D. Wasmuth

Publikováno v: Infect Immun

Heligmosomoides polygyrus is a helminth which naturally infects mice and is widely used as a laboratory model of chronic small intestinal helminth infection. While it is known that infection with H. polygyrus alters the composition of the host’s ba

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b52ec84d22c05398345a9172b3e1169d
https://doi.org/10.1128/iai.00225-21

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A49 CO-INFECTION WITH PARASITIC WORMS ENHANCES THE ABILITY OF SALMONELLA TO COLONIZE THE GUT LUMEN AND DEWORMING RESTORES COLONIZATION RESISTANCE TO SALMONELLA

Autor: Rachael D. FitzPatrick, Brandon E. Moeller, Mia H E Kennedy, Christoph H. Borchers, Lisa A. Reynolds, Katherine M Lawrence, Jun Han, Tara P. Brosschot

Background Chronic infections with intestinal helminths occur primarily in world regions where infections with bacterial pathogens are also common. Research so far has shown that helminths can promote bacterial infection, however, the precise mechani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ec2a4b1d442b9e59fea74f7f216deae
https://europepmc.org/articles/PMC7043462/

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A34 EOSINOPHILS ALTER STEADY-STATE SMALL INTESTINAL IL-1α AND IL-1β LEVELS BUT ARE NOT REQUIRED FOR THE MAINTENANCE OF IGA-SECRETING LAMINA PROPRIA-RESIDENT PLASMA CELLS, SECRETORY IGA OR SERUM IGA LEVELS

Autor: Lisa A. Reynolds, Tara P. Brosschot, Katherine M Lawrence, Mia H E Kennedy, Brandon E. Moeller, Rachael D. FitzPatrick, Courtney M. Gauthier

Background During homeostasis eosinophils are highly abundant in the lamina propria of the small intestine. Eosinophils have been reported to play a role in promoting barrier function in the steady state intestinal tract, and in the control of intest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c992c18434e13e81f09aa20323809f08
https://europepmc.org/articles/PMC7043687/

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Impaired host resistance to Salmonella during helminth co-infection is restored by anthelmintic treatment prior to bacterial challenge

Autor: Dongju Shin, Brandon E. Moeller, Katherine M Lawrence, Lisa A. Reynolds, Mia H E Kennedy, Courtney M. Gauthier, Kate M. E. Conway, Dominique M. Gatti, Rachael D. FitzPatrick, Tara P. Brosschot

Publikováno v: PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 15, Iss 1, p e0009052 (2021)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01e16992ae3a66f85d163d2e187eee01
https://doi.org/10.1371/journal.pntd.0009052

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