Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mia Eriksson"'
Publikováno v:
FEBS Open Bio, Vol 10, Iss 10, Pp 2166-2181 (2020)
Cysteine proteases are implicated in proteolysis events favoring cancer cell growth, spread, and death by apoptosis. Herein, we have studied whether the net growth and survival of the leukemic cell lines Jurkat, U937, and HL‐60 are affected by exte
Externí odkaz:
https://doaj.org/article/4d69b8fd0f4a49c382b10dc91825af33
Autor:
Ramprasad Ramakrishnan, Pablo Peña-Martínez, Puneet Agarwal, Maria Rodriguez-Zabala, Marion Chapellier, Carl Högberg, Mia Eriksson, David Yudovich, Mansi Shah, Mats Ehinger, Björn Nilsson, Jonas Larsson, Anna Hagström-Andersson, Benjamin L. Ebert, Ravi Bhatia, Marcus Järås
Publikováno v:
Cell Reports, Vol 31, Iss 8, Pp - (2020)
Summary: Acute myeloid leukemia (AML) is defined by an accumulation of immature myeloid blasts in the bone marrow. To identify key dependencies of AML stem cells in vivo, here we use a CRISPR-Cas9 screen targeting cell surface genes in a syngeneic ML
Externí odkaz:
https://doaj.org/article/833e4337d372485e83bc07664288cbbe
Autor:
Mia Eriksson, Pablo Peña-Martínez, Ramprasad Ramakrishnan, Marion Chapellier, Carl Högberg, Gabriella Glowacki, Christina Orsmark-Pietras, Talía Velasco-Hernández, Vladimir Lj Lazarević, Gunnar Juliusson, Jörg Cammenga, James C. Mulloy, Johan Richter, Thoas Fioretos, Benjamin L. Ebert, Marcus Järås
Publikováno v:
Blood Advances, Vol 1, Iss 23, Pp 2046-2057 (2017)
Abstract: Acute myeloid leukemia (AML) is associated with poor survival, and there is a strong need to identify disease vulnerabilities that might reveal new treatment opportunities. Here, we found that Toll-like receptor 1 (TLR1) and TLR2 are upregu
Externí odkaz:
https://doaj.org/article/71cdb79d494b42dc877ffcc4c6b15024
Autor:
Marion Chapellier, Pablo Peña-Martínez, Ramprasad Ramakrishnan, Mia Eriksson, Mehrnaz Safaee Talkhoncheh, Christina Orsmark-Pietras, Henrik Lilljebjörn, Carl Högberg, Anna Hagström-Andersson, Thoas Fioretos, Jonas Larsson, Marcus Järås
Publikováno v:
Haematologica, Vol 104, Iss 10 (2019)
Dysregulation of cytokines in the bone marrow (BM) microenvironment promotes acute myeloid leukemia (AML) cell growth. Due to the complexity and low throughput of in vivo stem-cell based assays, studying the role of cytokines in the BM niche in a scr
Externí odkaz:
https://doaj.org/article/27c172da456b48258fb009594489e036
Publikováno v:
FEBS Open Bio, Vol 10, Iss 10, Pp 2166-2181 (2020)
FEBS Open Bio
FEBS Open Bio
The secreted cysteine protease inhibitors, cystatin C and cystatin D, were added externally to leukemic U937, Jurkat, and HL‐60 cell cultures. The cystatins were internalized into endo‐lysosomal vesicles resulting in augmented hydrogen peroxide
Autor:
Anne Hultquist, Helena Sturesson, Jian Liu, Helena Ågerstam, Antoni Falqués-Costa, Axel Hyrenius-Wittsten, Mia Eriksson, Pauline Schneider, Marcus Järås, Mattias Pilheden, Cristian Garcia-Ruiz, Ronald W. Stam, Priscilla Wander, Henrik Lilljebjörn, Anna Hagström-Andersson
Publikováno v:
Leukemia
Autor:
Gunnar Juliusson, Carl Högberg, Gabriella Glowacki, Ramprasad Ramakrishnan, Marcus Järås, Christina Orsmark-Pietras, James C. Mulloy, Talia Velasco-Hernandez, Benjamin L. Ebert, Mia Eriksson, Thoas Fioretos, Marion Chapellier, Johan Richter, Vladimir Lazarevic, Jörg Cammenga, Pablo Peña-Martínez
Publikováno v:
Blood Advances. 1:2046-2057
Acute myeloid leukemia (AML) is associated with poor survival, and there is a strong need to identify disease vulnerabilities that might reveal new treatment opportunities. Here, we found that Toll-like receptor 1 (TLR1) and TLR2 are upregulated on p
Autor:
Mia Eriksson, Christina Orsmark-Pietras, Ramprasad Ramakrishnan, Marcus Järås, Thoas Fioretos, Marion Chapellier, Johan Richter, Anna Andersson, Pablo Peña-Martínez, Carl Högberg
Publikováno v:
Leukemia
Cytokines provide signals that regulate immature normal and acute myeloid leukemia (AML) cells in the bone marrow microenvironment. We here identify interleukin 4 (IL4) as a selective inhibitor of AML cell growth and survival in a cytokine screen usi
Autor:
Mia Eriksson
Publikováno v:
NORMA. 13:265-278
For feminist theory, the search for the material has often found its way via affect. As an immanent and seemingly pre-discursive and bodily experience, affects seem to offer a way out of the language and discourse trap. But should affect really be un
Autor:
Jonas Larsson, Henrik Lilljebjörn, Ramprasad Ramakrishnan, Anna Hagström-Andersson, Thoas Fioretos, Pablo Peña-Martínez, Mehrnaz Safaee Talkhoncheh, Marcus Järås, Mia Eriksson, Christina Orsmark-Pietras, Carl Högberg, Marion Chapellier
Publikováno v:
Haematologica
Dysregulation of cytokines in the bone marrow microenvironment promotes acute myeloid leukemia cell growth. Due to the complexity and low throughput of in vivo stem-cell based assays, studying the role of cytokines in the bone marrow niche in a scree