Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Mia Buehr"'
Autor:
Stephen Meek, Mia Buehr, Linda Sutherland, Alison Thomson, John J Mullins, Andrew J Smith, Tom Burdon
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14225 (2010)
The rat is the preferred experimental animal in many biological studies. With the recent derivation of authentic rat embryonic stem (ES) cells it is now feasible to apply state-of-the art genetic engineering in this species using homologous recombina
Externí odkaz:
https://doaj.org/article/8c371ef902a24926b1013cf4c7153a9b
Autor:
Linda Sutherland, Simon R. Tomlinson, Mia Buehr, Stephen Meek, Thomas G. Burdon, Jun Wei, Alison Thomson, Benedikt S. Nilges
Publikováno v:
STEM CELLS; Vol 31
Stabilization of β-catenin, through inhibition of glycogen synthase kinase 3 (GSK3) activity, in conjunction with inhibition of mitogen-activated protein kinase kinase 1/2 (MEK) promotes self-renewal of naïve-type mouse embryonic stem cells (ESC).
Autor:
Austin Smith, Mia Buehr
Publikováno v:
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 358:1397-1402
Embryonic stem (ES) cells are permanent pluripotent stem cell lines established from pre–implantation mouse embryos. There is currently great interest in the potential therapeutic applications of analogous cells derived from human embryos. The isol
Publikováno v:
Developmental Dynamics. 198:182-189
We have examined the numbers and distribution of primordial germ cells in We/We, We/+, and +/+ mouse embryos using Southern blotting to determine embryo genotypes. At early somite stages (5–7 somites: approximately 81/2 days post coitum [dpc]) ther
Autor:
Alison J. Thomson, John J. Mullins, Tom Burdon, Mia Buehr, Stephen Meek, Andrew J.H. Smith, Linda Sutherland
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14225 (2010)
Meek, S, Buehr, M, Sutherland, L, Thomson, A, Mullins, J J, Smith, A & Burdon, T 2010, ' Efficient Gene Targeting by Homologous Recombination in Rat Embryonic Stem Cells ', PLoS ONE, vol. 5, no. 12, e14225, pp.-. https://doi.org/10.1371/journal.pone.0014225
PLoS ONE
Meek, S, Buehr, M, Sutherland, L, Thomson, A, Mullins, J J, Smith, A & Burdon, T 2010, ' Efficient Gene Targeting by Homologous Recombination in Rat Embryonic Stem Cells ', PLoS ONE, vol. 5, no. 12, e14225, pp.-. https://doi.org/10.1371/journal.pone.0014225
PLoS ONE
The rat is the preferred experimental animal in many biological studies. With the recent derivation of authentic rat embryonic stem (ES) cells it is now feasible to apply state-of-the art genetic engineering in this species using homologous recombina
Publikováno v:
Reproduction, fertility, and development. 10(7-8)
In this study we have compared the in vitro differentiation potential of epiblast tissue from mouse and rat embryos. Epiblasts were isolated from egg cylinder stage embryos by microdissection and placed in culture. Rat cultures were distinguished by
Autor:
Mia Buehr
Publikováno v:
Experimental cell research. 232(2)
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 200(3)
Intracellular pH was measured in normal 8-cell stage mouse embryos and in embryos from a cross between DDK females and C3H males. DDK/C3H embryos display the DDK syndrome and spontaneously begin to decompact toward the late 16-cell stage. Ultimately,
Autor:
Anne McLaren, Mia Buehr
Publikováno v:
Cell differentiation and development : the official journal of the International Society of Developmental Biologists. 31(3)
Mouse gonadal tissue was studied under various conditions of in vitro culture, with the aim of clarifying some of the somatic-cell influences that regulate the development of germ cells in the mammalian gonad. Gonadal ridges, with or without the adja