Zobrazeno 1 - 10
of 16
pro vyhledávání: '"MiWei Hu"'
Autor:
Rachel E. Bennett, Miwei Hu, Analiese Fernandes, Marta Perez-Rando, Ashley Robbins, Tarun Kamath, Simon Dujardin, Bradley T. Hyman
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-16 (2020)
Abstract Microangiopathy, including proliferation of small diameter capillaries, increasing vessel tortuosity, and increased capillary blockage by leukocytes, was previously observed in the aged rTg4510 mouse model. Similar gene expression changes re
Externí odkaz:
https://doaj.org/article/abc4d2d9442f4705a8bfeb396fb4e6d4
Autor:
Annie G. Bryant, Miwei Hu, Becky C. Carlyle, Steven E. Arnold, Matthew P. Frosch, Sudeshna Das, Bradley T. Hyman, Rachel E. Bennett
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Alzheimer's Disease (AD) is associated with neuropathological changes, including aggregation of tau neurofibrillary tangles (NFTs) and amyloid-beta plaques. Mounting evidence indicates that vascular dysfunction also plays a key role in the pathogenes
Externí odkaz:
https://doaj.org/article/c6089f3c1f20402184532c77304f2623
Autor:
Rachel E. Bennett, Annie Bryant, Miwei Hu, Ashley B. Robbins, Sarah C. Hopp, Bradley T. Hyman
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-11 (2018)
Abstract Background Activation of inflammation pathways in the brain occurs in Alzheimer’s disease and may contribute to the accumulation and spread of pathological proteins including tau. The goal of this study was to identify how changes in micro
Externí odkaz:
https://doaj.org/article/d2d3815f75bf4f9caf6a00bc49ae9f81
Autor:
Alberto Serrano-Pozo, Zhaozhi Li, Maya E. Woodbury, Clara Muñoz-Castro, Astrid Wachter, Rojashree Jayakumar, Annie G. Bryant, Ayush Noori, Lindsay A. Welikovitch, Miwei Hu, Karen Zhao, Fan Liao, Gen Lin, Timothy Pastika, Joseph Tamm, Aicha Abdourahman, Taekyung Kwon, Rachel E. Bennett, Robert V. Talanian, Knut Biber, Eric H. Karran, Bradley T. Hyman, Sudeshna Das
Astrocytes play a critical role in brain homeostasis and normal functions but their changes along the spatiotemporal progression of Alzheimer’s disease (AD) neuropathology remain largely unknown. Here we performed single-nucleus RNA-sequencing on b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ae8088ede6648335195389c15bba7ec
https://doi.org/10.1101/2022.12.03.518999
https://doi.org/10.1101/2022.12.03.518999
Autor:
Bryant, Annie, Zhaozhi Li, Jayakumar, Rojashree, Serrano-Pozo, Alberto, Woost, Benjamin, Miwei Hu, Woodbury, Maya E., Wachter, Astrid, Lin, Gen, Taekyung Kwon, Talanian, Robert V., Biber, Knut, Karran, Eric H., Hyman, Bradley T., Das, Sudeshna, Bennett, Rachel E.
Publikováno v:
Journal of Neuroscience; 6/14/2023, Vol. 43 Issue 24, p4541-4557, 17p
Autor:
Miwei Hu, Marta Perez-Rando, Bradley T. Hyman, Ashley B. Robbins, Analiese R. Fernandes, Tarun V. Kamath, Rachel E. Bennett, Simon Dujardin
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-16 (2020)
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-16 (2020)
Microangiopathy, including proliferation of small diameter capillaries, increasing vessel tortuosity, and increased capillary blockage by leukocytes, was previously observed in the aged rTg4510 mouse model. Similar gene expression changes related to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9494a7682f0d24fc5bfd10771d4f021
https://doi.org/10.1186/s40478-020-01014-4
https://doi.org/10.1186/s40478-020-01014-4
Autor:
Bennett, Rachel E., Miwei Hu, Analiese Fernandes, Perez-Rando, Marta, Robbins, Ashley, Kamath, Tarun, Dujardin, Simon, Hyman, Bradley T.
Additional file 1: Supplementary Table 1. Neuropathological summary of human tissues included in these studies. Supplemental Figure 1. Western blot of total human tau in brain protein extracts. Supplemental Figure 2. Uncropped Western blots (from Fig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ed69ce6dcc8758f1800f33385c358a
Autor:
Ana C. Amaral, Bradley T. Hyman, Samantha B. Nicholls, Julia Schiantarelli, Zhanyun Fan, Molly J. Kirk, Ashley B. Robbins, Louis Delorme, Danny McKenzie, Nahel Tunio, Susanne Wegmann, Miwei Hu, Eloise Hudry, Rachel E. Bennett
Publikováno v:
Science Advances
Science advances 5(6), eaaw6404 (2019). doi:10.1126/sciadv.aaw6404
Science advances 5(6), eaaw6404 (2019). doi:10.1126/sciadv.aaw6404
We observed enhanced tau spreading in the aging mouse brain and tau misfolding in brain regions vulnerable in Alzheimer’s disease.
The incidence of Alzheimer’s disease (AD), which is characterized by progressive cognitive decline that correl
The incidence of Alzheimer’s disease (AD), which is characterized by progressive cognitive decline that correl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebb8596ab151a00a9cf08b827a83f41c
http://europepmc.org/articles/PMC6594764
http://europepmc.org/articles/PMC6594764
Autor:
Ashley B. Robbins, Rachel E. Bennett, Bradley T. Hyman, Annie Bryant, Miwei Hu, Sarah C. Hopp
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-11 (2018)
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-11 (2018)
Background Activation of inflammation pathways in the brain occurs in Alzheimer’s disease and may contribute to the accumulation and spread of pathological proteins including tau. The goal of this study was to identify how changes in microglia, a k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13267c6d65c7f136d23a9e041b56f43c
http://europepmc.org/articles/PMC6230271
http://europepmc.org/articles/PMC6230271