Zobrazeno 1 - 10
of 868
pro vyhledávání: '"MiR-29a"'
Autor:
Zsuzsanna Ujfaludi, Fruzsina Fazekas, Krisztina Biró, Orsolya Oláh-Németh, Istvan Buzogany, Farkas Sükösd, Tamás Beöthe, Tibor Pankotai
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The imperative need for sensitive and precise tools is underscored in cancer diagnostics, with biomarkers playing a pivotal role in facilitating early detection and tumor diagnosis. Despite their classical pathological classification, testic
Externí odkaz:
https://doaj.org/article/e86b17d6dad54aaabaed0532ec440d24
Publikováno v:
Animal Biotechnology, Vol 35, Iss 1 (2024)
MicroRNAs (miRNAs) were identified to be involved in various biological functions by regulating the degradation or suppressing the translation of their downstream target genes. Recent studies have identified miR-29a play a key role in functions of ma
Externí odkaz:
https://doaj.org/article/f1032141c2dc4d339fcae27c1a0f6140
Autor:
Ram Kumar, Himanshu Kamboj, Shweta Dhanda, Assim Verma, Yogesh Chander, Kuldeep Nehra, Adrish Bhati, Ramesh Kumar Dedar, Deepak Kumar Sharma, Sanjay Barua, Bhupendra N. Tripathi, Shalini Sharma, Naveen Kumar
Publikováno v:
Virulence, Vol 15, Iss 1 (2024)
ABSTRACTMicro RNAs (miRNAs) have been implicated in the regulation of maturation, proliferation, differentiation, and activation of immune cells. In this study, we demonstrated that miR-29a antagonizes IFN-γ production at early times post-LSDV infec
Externí odkaz:
https://doaj.org/article/18966d7cc2b74613bb6ea4a89349f960
Autor:
Yeke Wu, Bin Li, Disi Deng, Hongling Zhou, Min Liu, Huangping Ai, Yilin Xin, Weihan Hua, Lixing Zhao, Li Li
Publikováno v:
Autoimmunity, Vol 57, Iss 1 (2024)
AbstractMicroRNA (miRNA) plays a regulatory role in periodontitis. This study aimed to explore whether miR-29a could affect lipopolysaccharides (LPSs)-induced injury in human gingival fibroblasts (HGFs) through the competitive endogenous RNAs (ceRNA)
Externí odkaz:
https://doaj.org/article/a73a0ce5fec241dcb97dbb252ecd70f1
Autor:
Seung-Myoung Son, Jieun Yun, Dong-Wook Kim, Young-Suk Jung, Sang-Bae Han, Yong Hee Lee, Hye Sook Han, Chang Gok Woo, Ho-Chang Lee, Ok-Jun Lee
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Non-coding microRNAs (miRNAs) play critical roles in tumor progression and hold great promise as therapeutic agents for multiple cancers. MicroRNA 29a (miR-29a) is a tumor suppressor miRNA that inhibits cancer cell growth and tumo
Externí odkaz:
https://doaj.org/article/9aae04380f7c4f979df18e66f5383499
Autor:
Shuli Wang, Mulan Li, Pengcheng Liu, Yaning Dong, Ruishuang Geng, Tihua Zheng, Qingyin Zheng, Bo Li, Peng Ma
Publikováno v:
Experimental Gerontology, Vol 185, Iss , Pp 112349- (2024)
Age-related hearing loss (ARHL) is a common neurodegenerative disease. Its molecular mechanisms have not been fully elucidated. In the present study, we obtained differential mRNA expression in the cochlea of 2-month-old miR-29a+/+ mice and miR-29a
Externí odkaz:
https://doaj.org/article/827019b049ef4fed9d0c5289ad45d6d6
Autor:
Jinhui Lü, Qian Zhao, Yuefan Guo, Danni Li, Heying Xie, Cuicui Liu, Xin Hu, Suling Liu, Zhaoyuan Hou, Xunbin wei, Deyou Zheng, Richard G. Pestell, Zuoren Yu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-14 (2023)
Abstract Malignant breast cancer (BC) remains incurable mainly due to the cancer cell metastasis, which is mostly related to the status of Estrogen receptor alpha (ERα). However, our understanding of the mechanisms through which ERα regulates cance
Externí odkaz:
https://doaj.org/article/998422fd4681421aaf39adea8948da16
Autor:
Gary Hin-Fai Yam, Tianbing Yang, Moira L Geary, Mithun Santra, Martha Funderburgh, Elizabeth Rubin, Yiqin Du, Jose A Sahel, Vishal Jhanji, James L Funderburgh
Publikováno v:
Journal of Advanced Research, Vol 45, Iss , Pp 141-155 (2023)
Introduction: Corneal blindness due to scarring is treated with corneal transplantation. However, a global problem is the donor material shortage. Preclinical and clinical studies have shown that cell-based therapy using corneal stromal stem cells (C
Externí odkaz:
https://doaj.org/article/5b9861b24c7f4e1385e9d790328a6fb3
Publikováno v:
Smart Materials in Medicine, Vol 4, Iss , Pp 480-492 (2023)
Peripheral nerve injury (PNI) is a common surgical disease. In recent years, with the development of tissue engineering materials, nerve guidance conduit (NGC) is expected to replace autologous nerve transplantation and become a new method for the tr
Externí odkaz:
https://doaj.org/article/e29c9674a03c413caf83bdd43f92a62b
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 6 (2023)
Externí odkaz:
https://doaj.org/article/c84c16316be5421db294b6551270fa3f