Zobrazeno 1 - 10
of 21
pro vyhledávání: '"MiNa Baek"'
Autor:
Ji-Eun Park, Jiyeon Kim, MiNa Baek, Hyo-Jin An, Chan-Sung Park, Joon Young Jung, So-Young Kim, Yang Hee Kim
Publikováno v:
Toxicology Reports, Vol 13, Iss , Pp 101741- (2024)
Microbial fermentation has emerged as a pivotal process for sustainable production of essential goods and chemicals. Corynebacterium glutamicum is a proficient platform organism that contributes significantly to amino acid production through microbia
Externí odkaz:
https://doaj.org/article/1b3d6d461673479b80e8440c57de8d5a
Autor:
Mina Baek, Minjae Kim, Hae In Choi, Bert Binas, Junho Cha, Kyoung Hwa Jung, Sungkyoung Choi, Young Gyu Chai
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0301663 (2024)
The multikinase inhibitor sorafenib is the standard first-line treatment for advanced hepatocellular carcinoma (HCC), but many patients become sorafenib-resistant (SR). This study investigated the efficacy of another kinase inhibitor, regorafenib (Re
Externí odkaz:
https://doaj.org/article/6e5f5b67370e4b4a8c90946bb9101951
Analysis of differentially expressed long non-coding RNAs in LPS-induced human HMC3 microglial cells
Autor:
Mina Baek, Jin Choul Chai, Hae In Choi, Eunyoung Yoo, Bert Binas, Young Seek Lee, Kyoung Hwa Jung, Young Gyu Chai
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-13 (2022)
Abstract Background Long non-coding RNAs (lncRNAs) are emerging as key modulators of inflammatory gene expression, but their roles in neuroinflammation are poorly understood. Here, we identified the inflammation-related lncRNAs and correlated mRNAs o
Externí odkaz:
https://doaj.org/article/4b447e2a22fc4c1f8c16d2053af8ccaf
Autor:
Hae In Choi, Ga Yeong An, Eunyoung Yoo, Mina Baek, Bert Binas, Jin Choul Chai, Young Seek Lee, Kyoung Hwa Jung, Young Gyu Chai
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract The epigenetic reader, bromodomain-containing 4 (BRD4), is overexpressed in hepatocellular carcinoma (HCC), and BRD4 inhibition is considered as a new therapeutic approach. The BRD inhibitor JQ1 is known to inhibit the enrichment of BRD4 at
Externí odkaz:
https://doaj.org/article/bc8a76bc857d4853becf794c2332e593
Autor:
Hae In Choi, Ga Yeong An, Eunyoung Yoo, Mina Baek, Jin Choul Chai, Bert Binas, Young Seek Lee, Kyoung Hwa Jung, Young Gyu Chai
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The proto-oncogene MYC is important for development and cell growth, however, its abnormal regulation causes cancer. Recent studies identified distinct enhancers of MYC in various cancers, but any MYC enhancer(s) in hepatocellular carcinoma
Externí odkaz:
https://doaj.org/article/9974e4b284874109b71368bdac5f8f4c
Autor:
Hae In Choi, Ga Yeong An, Mina Baek, Eunyoung Yoo, Jin Choul Chai, Young Seek Lee, Kyoung Hwa Jung, Young Gyu Chai
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Hepatocellular carcinoma (HCC) is one of the most prevalent and poorly responsive cancers worldwide. Bromodomain and extraterminal (BET) inhibitors, such as JQ1 and OTX-015, inhibit BET protein binding to acetylated residues in histones. How
Externí odkaz:
https://doaj.org/article/2bf925a7b1f44275898bb8e721a341c7
Autor:
Mina Baek, Eunyoung Yoo, Hae In Choi, Ga Yeong An, Jin Choul Chai, Young Seek Lee, Kyoung Hwa Jung, Young Gyu Chai
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Microglia, resident macrophages of the brain that act as primary immune cells, play essential roles in innate immunity and neuroinflammatory pathologies. Microglial cells are rapidly activated in response to infection and inflammation/injury
Externí odkaz:
https://doaj.org/article/7a8daae75c6342daab790352521888f4
Autor:
Mina Baek, Jin Choul Chai, Hae In Choi, Eunyoung Yoo, Bert Binas, Young Seek Lee, Kyoung Hwa Jung, Young Gyu Chai
Publikováno v:
PLoS ONE, Vol 17, Iss 4, p e0266966 (2022)
Hepatocellular carcinoma (HCC) is the most common primary liver cancer and poor prognosis. Emerging evidence suggests that epigenetic alterations play a crucial role in HCC, suggesting epigenetic inhibition as a promising therapeutic approach. Indeed
Externí odkaz:
https://doaj.org/article/ab6ae6c231324f7ea66eb18c8a67e134
Publikováno v:
Amino Acids. 55:173-182
L-tryptophan has been used as a feed additive for swine and poultry and as a nutrient supplement for humans. However, some impurities in l-tryptophan have been reported as causative components of eosinophilia-myalgia syndrome. Therefore, from a safet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5078312e05e79c70562ec072f0971f56
https://doi.org/10.1007/s00726-022-03215-8
https://doi.org/10.1007/s00726-022-03215-8
Autor:
Choongrak Kim, Mina Baek
Publikováno v:
Journal of the Korean Statistical Society. 50:818-831
Clustering is an important statistical tool for the analysis of unsupervised data. Spectral clustering and stochastic block models, based on networks and graphs, are well established and widely used for community detection among many clustering algor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68caeb02fd05a69596119006a50759f8
https://doi.org/10.1007/s42952-021-00112-w
https://doi.org/10.1007/s42952-021-00112-w