Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Mi-kyung Yun"'
Publikováno v:
Child Health Nursing Research, Vol 26, Iss 2, Pp 154-163 (2020)
Purpose The purpose of this study was to investigate the effects of a positive psychology-based mental health promotion program for high school students. Methods This study used a randomized control group pretest-posttest design. A total of 47 high s
Externí odkaz:
https://doaj.org/article/c943ed99a29148b98e60fe756822eb48
Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation
Autor:
Maksym Tsytlonok, Hugo Sanabria, Yuefeng Wang, Suren Felekyan, Katherina Hemmen, Aaron H. Phillips, Mi-Kyung Yun, M. Brett Waddell, Cheon-Gil Park, Sivaraja Vaithiyalingam, Luigi Iconaru, Stephen W. White, Peter Tompa, Claus A. M. Seidel, Richard Kriwacki
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
The cyclin-dependent kinase (Cdk) inhibitor p27Kip1 (p27) folds upon binding to Cdk/cyclin complexes and during cell cycle progression p27 becomes phosphorylated, which triggers its ubiquitination and degradation. Here the authors use an integrated a
Externí odkaz:
https://doaj.org/article/68150062dc9d4c4082ba200461d73f70
Autor:
Shivendra Singh, Ahmed Abu-Zaid, Wenwei Lin, Jonathan Low, Alireza Abdolvahabi, Hongjian Jin, Qiong Wu, Bailey Cooke, Jie Fang, John Bowling, Sivaraja Vaithiyalingam, Duane Currier, Mi-Kyung Yun, Dinesh M. Fernando, Julie Maier, Heather Tillman, Purva Bulsara, Zhaohua Lu, Sourav Das, Anang Shelat, Zhenmei Li, Brandon Young, Richard Lee, Zoran Rankovic, Andrew J. Murphy, Stephen W. White, Andrew M. Davidoff, Taosheng Chen, Jun Yang
Publikováno v:
iScience, Vol 24, Iss 1, Pp 101996- (2021)
Summary: Histone lysine demethylases (KDMs) play critical roles in oncogenesis and therefore may be effective targets for anticancer therapy. Using a time-resolved fluorescence resonance energy transfer demethylation screen assay, in combination with
Externí odkaz:
https://doaj.org/article/06c582be98bb44abbf752e112dc13534
Autor:
Lalit Kumar Sharma, Chitra Subramanian, Mi-Kyung Yun, Matthew W. Frank, Stephen W. White, Charles O. Rock, Richard E. Lee, Suzanne Jackowski
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Mutations in pantotenate kinase (PANK) cause neurodegneration. Here the authors carry out achemical screen and identify a PANK activator that is orally available, crosses the blood brain barrierand show that it effecttive in improving pathology and l
Externí odkaz:
https://doaj.org/article/df56f7ef021a4881aab28f7777533ce7
FDI and Telecommunications Privatization: Case Studies of Latin America, United Kingdom, and Hungary
Autor:
Mi-Kyung Yun
Publikováno v:
East Asian Economic Review, Vol 2, Iss 4, Pp 131-155 (1998)
This thesis observed the recent trend of privatization and the effect of foreign investment, and the example of the overseas experience of sale of the state-own enterprises. To study the enlightenment of the strategy which attracted foreign investmen
Externí odkaz:
https://doaj.org/article/06c8e926a2b0407483e3b8cfd4fcdb73
Autor:
Rebecca M DuBois, P Jake Slavish, Brandi M Baughman, Mi-Kyung Yun, Ju Bao, Richard J Webby, Thomas R Webb, Stephen W White
Publikováno v:
PLoS Pathogens, Vol 8, Iss 8, p e1002830 (2012)
Emerging influenza viruses are a serious threat to human health because of their pandemic potential. A promising target for the development of novel anti-influenza therapeutics is the PA protein, whose endonuclease activity is essential for viral rep
Externí odkaz:
https://doaj.org/article/30fcbdf37e594ae99327103b81eb13cd
Autor:
Satyanarayana Pochampally, Kelli L. Hartman, Rui Wang, Jiaxing Wang, Mi-Kyung Yun, Keyur Parmar, Hyunseo Park, Bernd Meibohm, Stephen W. White, Wei Li, Duane D. Miller
Publikováno v:
ACS Pharmacology & Translational Science. 6:526-545
Autor:
Chitra Subramanian, Matthew W. Frank, Rajendra Tangallapally, Mi‐Kyung Yun, Stephen W. White, Richard E. Lee, Charles O. Rock, Suzanne Jackowski
Publikováno v:
Journal of Inherited Metabolic Disease. 46:28-42
Propionic acidemia (PA, OMIM 606054) is a devastating inborn error of metabolism arising from mutations that reduce the activity of the mitochondrial enzyme propionyl-CoA carboxylase (PCC). The defects in PCC reduce the concentrations of nonesterifie
Autor:
Philip M. Potter, Anang A. Shelat, Stephen W. White, R. Kiplin Guy, Daniel Savic, Taosheng Chen, Martine F. Roussel, Marie Morfouace, Richard E. Lee, Jun Yang, Vincent A. Boyd, Nagakumar Bharatham, Brandon M. Young, Jeanine E. Price, Jonathan A. Low, Kevin W. Freeman, Rachelle R. Olsen, William R. Shadrick, Zhenmei Li, Geoffrey Neale, Sourav Das, M. Brett Waddell, Michele Connelly, Sergio C. Chai, Barbara Jonchere, Nancy E. Martinez, Lyudmila Tsurkan, Mi-Kyung Yun, Liying Chi, P. Jake Slavish
Inhibition of members of the bromodomain and extraterminal (BET) family of proteins has proven a valid strategy for cancer chemotherapy. All BET identified to date contain two bromodomains (BD; BD1 and BD2) that are necessary for recognition of acety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5d71e4e32bd0d5208d4d9130ecd2d2
https://doi.org/10.1158/0008-5472.c.6511882.v1
https://doi.org/10.1158/0008-5472.c.6511882.v1
Autor:
Richard E. Lee, Jake Slavish, Brandon Young, Lei Yang, Sergio C. Chai, Marcus Fischer, Taosheng Chen, Zhenmei Li, Stephen W. White, Stanley Nithianantham, Jaeki Min, Gisele Nishiguchi, Seung Wook Yang, Patrick Ryan Potts, Marisa Actis, Shalandus H. Garrett, Jamie Jarusiewicz, Sourav Das, Martine F. Roussel, Barbara Jonchere, Anand Mayasundari, Yong Li, Mi-Kyung Yun, Xiang Fu, Fatemeh Keramatnia, Anang A. Shelat, Zoran Rankovic
Publikováno v:
Angew Chem Int Ed Engl
Targeting cereblon (CRBN) is currently one of the most frequently reported proteolysis-targeting chimera (PROTAC) approaches, owing to favorable drug-like properties of CRBN ligands, immunomodulatory imide drugs (IMiDs). However, IMiDs are known to b