Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Mi-Ok Lee"'
Autor:
Ohman Kwon, Hana Lee, Jaeeun Jung, Ye Seul Son, Sojeong Jeon, Won Dong Yoo, Naeun Son, Kwang Bo Jung, Eunho Choi, In-Chul Lee, Hyung-Jun Kwon, Chuna Kim, Mi-Ok Lee, Hyun-Soo Cho, Dae Soo Kim, Mi-Young Son
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Three-dimensional human intestinal organoids (hIO) are widely used as a platform for biological and biomedical research. However, reproducibility and challenges for large-scale expansion limit their applicability. Here, we establish a human
Externí odkaz:
https://doaj.org/article/6f5d70098bfd4eaabe1920746c0323fc
Autor:
Youngsun Lee, Mi-Ok Lee
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S112-S113 (2023)
Externí odkaz:
https://doaj.org/article/5e714ca2b24d427b9992c308262f690b
Publikováno v:
Stem Cell Research, Vol 68, Iss , Pp 103045- (2023)
Telomeric repeat binding factor 1 (TRF1) plays an essential role in maintaining telomere length. Here, we established TRF1-knockout human pluripotent stem cells (hPSCs; hTRF1-KO) using the CRISPR/Cas9 technology. The hTRF1-KO cell lines expressed plu
Externí odkaz:
https://doaj.org/article/541c78c9a1014572a9d2ef32fc33f92f
Publikováno v:
Fisheries and Aquatic Sciences, Vol 24, Iss 8, Pp 277-283 (2021)
Kudoa septempunctata has been reported as a new parasite in aquacultured olive flounder Paralichthys olivaceus, and also as a causative agent of food poisoning in humans. This paper investigated the infection of K. septempunctata in 216 sashimi an
Externí odkaz:
https://doaj.org/article/994b1a404c154dcda0b17513c0cf1ea0
Autor:
Mi-Ok Lee, Su-gi Lee, Cho-Rok Jung, Ye Seul Son, Jae-Woon Ryu, Kwang Bo Jung, Jun-Ho Ahn, Jung-Hwa Oh, Hyang-Ae Lee, Jung Hwa Lim, Janghwan Kim, Insu Jang, Jinhyuk Choi, Jaeeun Jung, Kunhyang Park, Byungwook Lee, Dae-Soo Kim, Mi-Young Son, Hyun-Soo Cho
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Quantitative methods to assess the quality of hPSC-derived organoids have not been developed. Here they present a prediction algorithm to assess the transcriptomic similarity between hPSC-derived organoids and the corresponding human target organs an
Externí odkaz:
https://doaj.org/article/27708e935ee5482783e2d1c6359a3d60
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Brain organoids are valuable research models for human development and disease since they mimic the various cell compositions and structures of the human brain; however, they have challenges in presenting aging phenotypes for degenerative diseases. T
Externí odkaz:
https://doaj.org/article/eac0293668bc4ef3a106821424910a14
Autor:
Mi-Ok Lee, Kwang Bo Jung, Seong-Jae Jo, Sung-Ae Hyun, Kyoung-Sik Moon, Joung-Wook Seo, Sang-Heon Kim, Mi-Young Son
Publikováno v:
Journal of Biological Engineering, Vol 13, Iss 1, Pp 1-17 (2019)
Abstract Background Cardiac fibrosis is the most common pathway of many cardiac diseases. To date, there has been no suitable in vitro cardiac fibrosis model that could sufficiently mimic the complex environment of the human heart. Here, a three-dime
Externí odkaz:
https://doaj.org/article/8b166fb48b1f48e3a935946d0fc701ed
Autor:
Jeongmin Ha, Ji Su Kang, Minhyung Lee, Areum Baek, Seongjun Kim, Sun-Ku Chung, Mi-Ok Lee, Janghwan Kim
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Although brain organoids are an innovative technique for studying human brain development and disease by replicating the structural and functional properties of the developing human brain, some limitations such as heterogeneity and long-term differen
Externí odkaz:
https://doaj.org/article/ca6f050a49ae4d26b042cedfcaa24041
Autor:
Seung-Ju Cho, Keun-Tae Kim, Ho-Chang Jeong, Ju-Chan Park, Ok-Seon Kwon, Yun-Ho Song, Joong-Gon Shin, Seungmin Kang, Wankyu Kim, Hyoung Doo Shin, Mi-Ok Lee, Sung-Hwan Moon, Hyuk-Jin Cha
Publikováno v:
Stem Cell Reports, Vol 11, Iss 5, Pp 1244-1256 (2018)
Summary: The selective survival advantage of culture-adapted human embryonic stem cells (hESCs) is a serious safety concern for their clinical application. With a set of hESCs with various passage numbers, we observed that a subpopulation of hESCs at
Externí odkaz:
https://doaj.org/article/592605e5a71c47feab63b767afa74cf0
Autor:
Kwang Bo Jung, Hana Lee, Ye Seul Son, Mi-Ok Lee, Young-Dae Kim, Soo Jin Oh, Ohman Kwon, Sunwha Cho, Hyun-Soo Cho, Dae-Soo Kim, Jung-Hwa Oh, Matthias Zilbauer, Jeong-Ki Min, Cho-Rok Jung, Janghwan Kim, Mi-Young Son
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Human pluripotent stem cell-derived intestinal organoids (hIOs) are a useful model with which to study intestinal development and disease, but they require in vivo maturation to resemble adult tissue. Here, the authors show that T lymphocyte-derived
Externí odkaz:
https://doaj.org/article/a475745ef0d7496ba465e8488bf0de6b