Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mi-Mi Su"'
Publikováno v:
Sensors and Actuators B: Chemical. 276:456-465
A selective probe with a significant regioselective turn-on response, CP-1, has been developed for detection of H2S from biothiols. CP-1 features superb selectivity to H2S, a wide pH range and low cytotoxicity. CP-1 has over 10000-fold selectivity fo
Publikováno v:
Analytica Chimica Acta. 1043:123-131
Pre-clinical diagnosis of many diseases required quantitative detection of Human Serum Albumin (HSA). Herein a high-selective HSA sensor RhHSA was picked through a two-round selectivity evolution from the typical "Effector-π-Trigger" style. RhHSA su
Publikováno v:
European Journal of Medicinal Chemistry. 155:725-735
A series of novel selective BRAFV600E inhibitory agents (Compound 1–16) 5-(2,3-dihydrobenzo[b][1,4]dioxane-6-yl)-N,3-diaryl-4,5-dihydro-1H-pyrazole-1-carbothioamides have been designed and synthesized. Their anti-proliferation and BRAF inhibitory a
Publikováno v:
Organic & Biomolecular Chemistry. 16:8318-8324
A rapid cell-permeating probe NJUXJ-1 was introduced for sensitive and selective detection of sulfite in living cells. It generated a turn-on response to sulfite with high sensitivity (detection limit 13.0 nM) and selectivity (at a physiological leve
Publikováno v:
Bioorganic chemistry. 93
The antibacterial agents and therapies today are facing serious problems such as drug resistance. Introducing dual inhibiting effect is a valid approach to solve this trouble and bring advantages including wide adaptability, favorable safety and supe
Publikováno v:
Genes & Genomics. 38:1121-1128
The plant Schisandra chinensis contains a phytoestrogens, a type of naturally occurring estrogens which have multiple functions in a number of biological processes. To investigate the correlation between phytoestrogens and epigenetic modification, es
Publikováno v:
Bioorganicmedicinal chemistry letters. 28(19)
By recruiting the important moiety from Shikonin, a series of novel oxoindoline derivatives S1–S20 have been synthesized for inhibiting H. pylori urease. The most potent compound S18 displayed better activity (IC50 = 0.71 μM; MIC = 0.48 μM) than
Publikováno v:
European journal of medicinal chemistry. 155
A series of novel selective BRAF
Autor:
Wei Zhang, Yuan-Yuan Li, Qing-Hua Shang, Lin Qi, Mi-Mi Sun, Gang Chen, Yong An, Jing-Xin Li, Wang-Ping Jia, Zhong-An Sun, Hui-Bin Xu, Qing-Mei Gao, Li Tang, Xiao-Wen Wang, Ji-Yuan Zhang, Yi-Ming Mu, Fu-Sheng Wang
Publikováno v:
Annals of Hepatology, Vol 27, Iss 6, Pp 100745- (2022)
Introduction and Objectives: Hepatitis B surface antigen (HBsAg) clearance, indicating functional cure or resolved chronic hepatitis B (CHB), remains difficult to achieve via nucleos(t)ide analogue monotherapy. We investigated whether metformin add-o
Externí odkaz:
https://doaj.org/article/9c69443fceee48998bb5b6144549de20
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 4, p 2273 (2022)
Phosphorus is an essential macronutrient for plants. The phosphate (Pi) concentration in soil solutions is typically low, and plants always suffer from low-Pi stress. During Pi starvation, a number of adaptive mechanisms in plants have evolved to inc
Externí odkaz:
https://doaj.org/article/c581618f77614e209c51d6e93e0e2b69