Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Mi-Kyoung Seo"'
Autor:
Dawoon E. Jung, Mi-Kyoung Seo, Jung Hyun Jo, Kahee Kim, Chanyang Kim, Hyundeok Kang, Soo Been Park, Hee Seung Lee, Sangwoo Kim, Si Young Song
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-14 (2024)
Abstract Discovery and verification of diagnostic or therapeutic biomarkers for biliary tract cancer (BTC) is challenging owing to the low prevalence of the disease. Here, we identified and investigated the clinical impact of a fusion gene, Pumilio1-
Externí odkaz:
https://doaj.org/article/87b16b76ddf34dcdb212978e21fcc41d
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-12 (2024)
Abstract Gene expression analysis enhances proper cancer subtyping, a better understanding of the molecular characteristics of cancer, and strategies for precision medicine. However, salivary gland cancer (SGC) subtyping remains largely unexplored be
Externí odkaz:
https://doaj.org/article/0e53d96e2525472ea73fa750f3c24330
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Detecting microsatellite instability (MSI) in colorectal cancers (CRCs) is essential because it is the determinant of treatment strategies, including immunotherapy and chemotherapy. Yet, no attempt has been made to exploit transcriptomic pro
Externí odkaz:
https://doaj.org/article/824666ac97524c649a7ccbc739aaef87
Autor:
Hyundeok Kang, Mi-Kyoung Seo, BeumJin Park, Sun Och Yoon, Yoon Woo Koh, Dahee Kim, Sangwoo Kim
Publikováno v:
Translational Oncology, Vol 24, Iss , Pp 101496- (2022)
Introduction: Characterizing the tumor microenvironment (TME) and immune landscape of cancer has been a promising step towards discovering new therapeutic biomarkers and guiding precision medicine; however, its application in mucoepidermoid carcinoma
Externí odkaz:
https://doaj.org/article/eaa4b86044f94ee89078c04995445383
Autor:
BeumJin Park, Seok-Jae Heo, Yong Joon Lee, Mi-Kyoung Seo, Jiyun Hong, Eui-Cheol Shin, Inkyung Jung, Sangwoo Kim
Publikováno v:
iScience, Vol 25, Iss 6, Pp 104467- (2022)
Summary: CD8+ T cells recognize and kill tumor cells with HLA-I tumor antigens in early tumorigenesis, the efficiency of which differs according to antigen-recognition coverage, as shown in earlier tumor onset in HLA-I homozygosity. However, the univ
Externí odkaz:
https://doaj.org/article/e091d2774e8941cfa11d6b252a19614d
Autor:
Tae-Min Kim, In Seok Yang, Byung-Joon Seung, Sejoon Lee, Dohyun Kim, Yoo-Jin Ha, Mi-kyoung Seo, Ka-Kyung Kim, Hyun Seok Kim, Jae-Ho Cheong, Jung-Hyang Sur, Hojung Nam, Sangwoo Kim
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Comparison of spontaneous canine cancers and human cancers may illuminate future therapeutic avenues. Here, genomic analyses of these tumors highlights a convergence on PI3K-Akt oncogenic pathways.
Externí odkaz:
https://doaj.org/article/ab1a0a9b68044115ac3ec182334e71fc
Publikováno v:
Clinical Psychopharmacology and Neuroscience. 20:228-239
Bipolar disorder is a mental illness that causes extreme mood swings and has a chronic course. However, the mechanism by which mood episodes with completely opposite characteristics appear repeatedly, or a mixture of symptoms appears, in patients wit
Publikováno v:
Mood and Emotion. 20:8-14
Autor:
Ji Ae Lee, Mi-Kyoung Seo, Seung-Yeon Yoo, Nam-Yun Cho, Yoonjin Kwak, Kyoungbun Lee, Jung Ho Kim, Gyeong Hoon Kang
Publikováno v:
Virchows Archiv. 480:543-555
Caudal-type homeobox 2 (CDX2), special AT-rich sequence-binding protein 2 (SATB2), and keratin 20 (KRT20) are frequently used as intestinal epithelium-specific markers in immunohistochemical studies. However, subsets of colorectal carcinomas (CRCs) s
Autor:
Seo-Young Lee, Yeojin Bang, Wongi Seol, Janghwan Kim, Hye-Jung Kim, Hyuna Sim, Mi Kyoung Seo, Hyun Jin Choi, Ilhong Son, Sun-Ku Chung, Juhee Lim, Joo-Eun Lee, Daleum Nam, Sung Woo Park
Publikováno v:
Experimental Neurobiology
Mutations in the Leucine-rich repeat kinase 2 (LRRK2) gene are the most prevalent cause of familial Parkinson’s disease (PD). The increase in LRRK2 kinase activity observed in the pathogenic G2019S mutation is important for PD development. Several