Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Mi-Heon Lee"'
Autor:
Jean Philippe Nesseler, MD, Dorthe Schaue, PhD, William H. McBride, PhD, DSc, Mi-Heon Lee, PhD, Tania Kaprealian, MD, Simone P. Niclou, PhD, Philippe Nickers, MD, PhD
Publikováno v:
Advances in Radiation Oncology, Vol 4, Iss 2, Pp 268-282 (2019)
Purpose: Glioblastoma (GBM) remains an incurable disease despite extensive treatment with surgical resection, irradiation, and temozolomide. In line with many other forms of aggressive cancers, GBM is currently under consideration as a target for imm
Externí odkaz:
https://doaj.org/article/7874013381ef4aa4b84a30f7c17e7b00
Autor:
Jean Philippe Nesseler, Mi-Heon Lee, Christine Nguyen, Anusha Kalbasi, James W. Sayre, Tahmineh Romero, Philippe Nickers, William H. McBride, Dörthe Schaue
Publikováno v:
Cancers, Vol 12, Iss 3, p 714 (2020)
The purpose of this study was to determine the dynamic contributions of different immune cell subsets to primary and abscopal tumor regression after hypofractionated radiation therapy (hRT) and the impact of anti-PD-1 therapy. A bilateral syngeneic F
Externí odkaz:
https://doaj.org/article/ebecdd9f900445cc8236a92072eb1da9
Publikováno v:
Molecular Imaging, Vol 6 (2007)
Recruitment of CD4 + T cells into islets is a critical component of islet inflammation (insulitis) leading to type 1 diabetes; therefore, determining if conditions used to treat diabetes change their trafficking patterns is relevant to the outcome. C
Externí odkaz:
https://doaj.org/article/050dbb5be7f74f088047b2e76c0eb7b1
Autor:
Steven M. Dubinett, Michael C. Fishbein, Long-sheng Hong, John D. Minna, Jill E. Larsen, Jerry W. Shay, Brigitte N. Gomperts, Aik T. Ooi, John A. Belperio, Mi-Heon Lee, Sherven Sharma, Li X. Zhu, Kostyantyn Krysan, Gerald Wang, Natalie Yakobian, Ying Q. Lin, Linh M. Tran, Zhe Jing, Tonya C. Walser
Figures S5-S6 provide additional evidence that Snail malignantly transforms epithelial cells in vitro. Information on the mutational background and stem phenotype of the cells transformed by Snail is provided.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b5e4c0d8e24d65d88032e6c01476ad0
https://doi.org/10.1158/0008-5472.22417908.v1
https://doi.org/10.1158/0008-5472.22417908.v1
Autor:
Steven M. Dubinett, Michael C. Fishbein, Long-sheng Hong, John D. Minna, Jill E. Larsen, Jerry W. Shay, Brigitte N. Gomperts, Aik T. Ooi, John A. Belperio, Mi-Heon Lee, Sherven Sharma, Li X. Zhu, Kostyantyn Krysan, Gerald Wang, Natalie Yakobian, Ying Q. Lin, Linh M. Tran, Zhe Jing, Tonya C. Walser
Detailed supplemental methods and key references are provided. Tables S1-S2-S3-S4 provide antibody information, mouse study design information, PCR primer information, and an abbreviations list, respectively.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83451d620ff25527355c35e240366d6e
https://doi.org/10.1158/0008-5472.22417905.v1
https://doi.org/10.1158/0008-5472.22417905.v1
Autor:
Steven M. Dubinett, Michael C. Fishbein, Long-sheng Hong, John D. Minna, Jill E. Larsen, Jerry W. Shay, Brigitte N. Gomperts, Aik T. Ooi, John A. Belperio, Mi-Heon Lee, Sherven Sharma, Li X. Zhu, Kostyantyn Krysan, Gerald Wang, Natalie Yakobian, Ying Q. Lin, Linh M. Tran, Zhe Jing, Tonya C. Walser
Epithelial-to-mesenchymal transition (EMT) is organized in cancer cells by a set of key transcription factors, but the significance of this process is still debated, including in non–small cell lung cancer (NSCLC). Here, we report increased express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c1e7d22477eef4683564e483d28fcdd
https://doi.org/10.1158/0008-5472.c.6509976
https://doi.org/10.1158/0008-5472.c.6509976
Autor:
Steven M. Dubinett, Michael C. Fishbein, Long-sheng Hong, John D. Minna, Jill E. Larsen, Jerry W. Shay, Brigitte N. Gomperts, Aik T. Ooi, John A. Belperio, Mi-Heon Lee, Sherven Sharma, Li X. Zhu, Kostyantyn Krysan, Gerald Wang, Natalie Yakobian, Ying Q. Lin, Linh M. Tran, Zhe Jing, Tonya C. Walser
Figures S2-S3-S4 provide additional evidence that Snail is a potent driver of EMT, carcinogenic signaling programs, and stem cell expansion in vitro.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eaf0657c61f29c6de27d8c3fbe3374e
https://doi.org/10.1158/0008-5472.22417911
https://doi.org/10.1158/0008-5472.22417911
Autor:
Steven M. Dubinett, Michael C. Fishbein, Long-sheng Hong, John D. Minna, Jill E. Larsen, Jerry W. Shay, Brigitte N. Gomperts, Aik T. Ooi, John A. Belperio, Mi-Heon Lee, Sherven Sharma, Li X. Zhu, Kostyantyn Krysan, Gerald Wang, Natalie Yakobian, Ying Q. Lin, Linh M. Tran, Zhe Jing, Tonya C. Walser
Figure S8 provides evidence that ESRP1 loss alone (without Snail expression) is not sufficient to transform epithelial cells in vitro.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0302b83de5f56c3e8dcbbefb5e0f3aa4
https://doi.org/10.1158/0008-5472.22417914.v1
https://doi.org/10.1158/0008-5472.22417914.v1
Autor:
Tania Kaprealian, Simone P. Niclou, Philippe Nickers, Mi-Heon Lee, Dörthe Schaue, William H. McBride, J.P. Nesseler
Publikováno v:
Advances in Radiation Oncology, Vol 4, Iss 2, Pp 268-282 (2019)
Advances in radiation oncology, vol 4, iss 2
Advances in Radiation Oncology
Advances in radiation oncology, vol 4, iss 2
Advances in Radiation Oncology
Purpose Glioblastoma (GBM) remains an incurable disease despite extensive treatment with surgical resection, irradiation, and temozolomide. In line with many other forms of aggressive cancers, GBM is currently under consideration as a target for immu
Autor:
Christine Nguyen, Anusha Kalbasi, Tahmineh Romero, James Sayre, J.P. Nesseler, Mi-Heon Lee, Dörthe Schaue, William H. McBride, Philippe Nickers
Publikováno v:
Cancers
Volume 12
Issue 3
Cancers, Vol 12, Iss 3, p 714 (2020)
Cancers, vol 12, iss 3
Volume 12
Issue 3
Cancers, Vol 12, Iss 3, p 714 (2020)
Cancers, vol 12, iss 3
The purpose of this study was to determine the dynamic contributions of different immune cell subsets to primary and abscopal tumor regression after hypofractionated radiation therapy (hRT) and the impact of anti-PD-1 therapy. A bilateral syngeneic F