Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Mi Sun Jin"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract ATP-binding cassette transporter B6 (ABCB6), a protein essential for heme biosynthesis in mitochondria, also functions as a heavy metal efflux pump. Here, we present cryo-electron microscopy structures of human ABCB6 bound to a cadmium Cd(II
Externí odkaz:
https://doaj.org/article/249cbce68a644e058fbf6485061937cb
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract Human ATP-binding cassette transporter subfamily B6 (ABCB6) is a mitochondrial ATP-driven pump that translocates porphyrins from the cytoplasm into mitochondria for heme biosynthesis. Within the transport pathway, a conserved aromatic residu
Externí odkaz:
https://doaj.org/article/04521680c57f4d6c83849687550b8191
Autor:
Eunhong Jang, Miriam Lee, So Young Yoon, Sang Soo Lee, Jongseo Park, Mi Sun Jin, Soo Hyun Eom, Changwook Lee, Youngsoo Jun
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108386- (2023)
Summary: The endoplasmic reticulum (ER) consists of the nuclear envelope and a connected peripheral network of tubules and interspersed sheets. The structure of ER tubules is generated and maintained by various proteins, including reticulons, DP1/Yop
Externí odkaz:
https://doaj.org/article/ec4f300a09d64c3794511409eb1648fa
Autor:
Jun Gyou Park, Songwon Kim, Eunhong Jang, Seung Hun Choi, Hyunsu Han, Seulgi Ju, Ji Won Kim, Da Sol Min, Mi Sun Jin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
In this work, the authors report an ATP-dependent phosphatidylserine floppase activity for the lysosomal ATP-binding cassette transporter TAPL. In addition, they report the cryo-EM structures of mouse TAPL complexed with (i) phospholipid, (ii) choles
Externí odkaz:
https://doaj.org/article/9f2c63bf6d164a5aa7c5c3cc9c3884d9
Autor:
Jung-Ah Kang, Songwon Kim, Minji Park, Hyun-Jin Park, Jeong-Hyun Kim, Sanghyeok Park, Jeong-Ryul Hwang, Yong-Chul Kim, Yoon Jun Kim, Yuri Cho, Mi Sun Jin, Sung-Gyoo Park
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Current treatments for chronic hepatitis B virus (HBV) infection are not curative. Here, the authors show that an antifungal drug, ciclopirox, inhibits HBV capsid assembly and synergizes with nucleoside/nucleotide analogs to prevent HBV replication i
Externí odkaz:
https://doaj.org/article/c10c1a7e6f104a508eca916208b6abe6
Publikováno v:
Pharmaceuticals, Vol 15, Iss 4, p 440 (2022)
N6A-methyladenosine (m6A) post-transcriptional modification, the most abundant internal RNA modification, is catalyzed by the METTL3-14 methyltransferase complex. Recently, attention has been drawn to the METTL3-14 complex regarding its significant r
Externí odkaz:
https://doaj.org/article/f3f711aa9779494c807ddc684e874a6b
Autor:
Wonseok Hwang, Jungmin Yoo, Yuno Lee, Suyeon Park, Phuong Lien Hoang, HyeokJin Cho, Jeongmin Yu, Thi Minh Hoa Vo, Minsang Shin, Mi Sun Jin, Daeho Park, Changbong Hyeon, Gwangrog Lee
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Metal ions at the active site of an enzyme act as cofactors and their dynamic fluctuations might influence enzyme activity. Here authors use single-molecule FRET to study λ-exonuclease and find that metal-ion-coordination is correlated with enzymati
Externí odkaz:
https://doaj.org/article/2a0749b91eb14221840220e83adac0c3
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract The sodium-dependent citrate transporter of Klebsiella pneumoniae (KpCitS) belongs to the 2-hydroxycarboxylate transporter (2-HCT) family and allows the cell to use citrate as sole carbon and energy source in anaerobic conditions. Here we pr
Externí odkaz:
https://doaj.org/article/784b69cee4a042e8be3b47f52c78fa74
Publikováno v:
Biomedicines, Vol 8, Iss 5, p 96 (2020)
Conjugation of serum albumin or one of its ligands (such as fatty acid) has been an effective strategy to prolong the serum half-lives of drugs via neonatal Fc receptor (FcRn)–mediated recycling of albumin. So far, fatty acid (FA) has been effectiv
Externí odkaz:
https://doaj.org/article/3797cd32738e499087df782428c778e0
Autor:
Lee, Narasaem, Subin Kim, Na Young Lee, Heeji Jo, Pyeonghwa Jeong, Pagire, Haushabhau S., Pagire, Suvarna H., Jin Hee Ahn, Mi Sun Jin, Chul-Seung Park
Publikováno v:
Life Science Alliance; Oct2024, Vol. 7 Issue 10, p1-13, 13p