Zobrazeno 1 - 10 of 88 pro vyhledávání: '"Mi Suk, Jeong"'
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Structural basis of the oncogenic KRAS mutant and GJ101 complex
Autor: Hyeon Jin Kim, Chang Woo Han, Mi Suk Jeong, Se Bok Jang
Publikováno v: Biochemical and Biophysical Research Communications. 641:27-33
KRAS mutations occur in a quarter of all human cancers. When activated in its GTP-bound form, RAS stimulates diverse cellular systems, such as cell division, differentiation, growth, and apoptosis through the activations of various signaling pathways
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80aa732f99e52d9fafb6b5295e7efab8
https://doi.org/10.1016/j.bbrc.2022.12.019
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4
DED Interaction of FADD and Caspase-8 in the Induction of Apoptotic Cell Death
Autor: Young-Hoon, Park, Chang Woo, Han, Mi Suk, Jeong, Se Bok, Jang
Publikováno v: Journal of Microbiology and Biotechnology. 32:1034-1040
Fas-associated death domain (FADD) is an adapter molecule that bridges the interaction between receptor-interacting protein 1 (RIP1) and aspartate-specific cysteine protease-8 (caspase-8). As the primary mediator of apoptotic cell death, caspase-8 ha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee68fef8685bb17a7e2e4442ea76500
https://doi.org/10.4014/jmb.2206.06003
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Akademický článek
Understand KRAS and the Quest for Anti-Cancer Drugs
Autor: Chang Woo Han, Mi Suk Jeong, Se Bok Jang
Publikováno v: Cells, Vol 10, Iss 4, p 842 (2021)
The KRAS oncogene is mutated in approximately ~30% of human cancers, and the targeting of KRAS has long been highlighted in many studies. Nevertheless, attempts to target KRAS directly have been ineffective. This review provides an overview of the st
Externí odkaz: https://doaj.org/article/5fce3a84e6b74f6b88cba955e4960685
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