Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Mi Ran, Yun"'
Autor:
Sun Min Lim, Stefanie S. Schalm, Eun Ji Lee, Sewon Park, Chiara Conti, Yves A. Millet, Rich Woessner, Zhuo Zhang, Luz E. Tavera-Mendoza, Faith Stevison, Faris Albayya, Thomas A. Dineen, John Hsieh, Seung Yeon Oh, Alena Zalutskaya, Julia Rotow, Koichi Goto, Dae-Ho Lee, Mi Ran Yun, Byoung Chul Cho
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Introduction: Despite the availability of several epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs), most patients with non-small-cell lung cancer (NSCLC) eventually develop resistance to these agents. Notably, EGFR _C797S mut
Externí odkaz:
https://doaj.org/article/a9dcec66ffca44c6854af71897c42a4e
Autor:
Wongeun Lee, Dong Kwon Kim, Chun-Bong Synn, Hee Kyu Lee, Sungho Park, Dong-Sik Jung, Yewon Choi, Jae Hwan Kim, Youngseon Byeon, Young Seob Kim, Seul Lee, Soyeon Lee, Yunjoo Joo, Eun Ji Lee, Mi Ran Yun, Seong Gu Heo, Wookyeom Yang, Ji Eun Jung, Eun Kyung Kim, Jooyeon Park, June Dong Park, Doo Jae Lee, Hyeon-Woo Kim, Sun Min Lim, Min Hee Hong, Beung-Chul Ahn, Jii Bum Lee, Kyoung-Ho Pyo
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
A recently developed treatment strategy for lung cancer that combines immune checkpoint inhibitors with chemotherapy has been applied as a standard treatment for lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC), and it has improved
Externí odkaz:
https://doaj.org/article/407f5970dae34dc5907c67d56bd5e79e
Autor:
Sun Min Lim, San-Duk Yang, Sangbin Lim, Seong Gu Heo, Stetson Daniel, Aleksandra Markovets, Rafati Minoo, Kyoung-Ho Pyo, Mi Ran Yun, Min Hee Hong, Hye Ryun Kim, Byoung Chul Cho
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Introduction: Osimertinib is a third-generation EGFR tyrosine kinase inhibitor (TKI) that is approved for the use of EGFR -mutant non-small cell lung cancer (NSCLC) patients. In this study, we investigated the acquired resistance mechanisms in NSCLC
Externí odkaz:
https://doaj.org/article/2422d3288270447897efe41264d6b211
Autor:
Han Na Kang, Jae-Hwan Kim, A-Young Park, Jae Woo Choi, Sun Min Lim, Jinna Kim, Eun Joo Shin, Min Hee Hong, Kyoung-Ho Pyo, Mi Ran Yun, Dong Hwi Kim, Hanna Lee, Sun Och Yoon, Da Hee Kim, Young Min Park, Hyung Kwon Byeon, Inkyung Jung, Soonmyung Paik, Yoon Woo Koh, Byoung Chul Cho, Hye Ryun Kim
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background We investigated whether head and neck squamous cell carcinoma (HNSCC) patient-derived xenografts (PDXs) reaffirm patient responses to anti-cancer therapeutics. Methods Tumors from HNSCC patients were transplanted into immunodefici
Externí odkaz:
https://doaj.org/article/d789d28930c4424bb99a3602f9eb9a8f
Autor:
Chun‐Bong Synn, Sung Eun Kim, Hee Kyu Lee, Min‐Hwan Kim, Jae Hwan Kim, Ji Min Lee, Ha Ni Jo, Wongeun Lee, Dong Kwon Kim, Youngseon Byeon, Young Seob Kim, Mi Ran Yun, Chae‐Won Park, Jiyeon Yun, Sangbin Lim, Seong Gu Heo, San‐Duk Yang, Eun Ji Lee, Seul Lee, Hunmi Choi, You Won Lee, Jae Seok Cho, Do Hee Kim, Sungho Park, Jung‐Ho Kim, Yewon Choi, Sung Sook Lee, Beung‐Chul Ahn, Chang Gon Kim, Sun Min Lim, Min Hee Hong, Hye Ryun Kim, Kyoung‐Ho Pyo, Byoung Chul Cho
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 1, Pp n/a-n/a (2022)
Abstract Objectives AXL‐mediated activation of aberrant tyrosine kinase drives various oncogenic processes and facilitates an immunosuppressive microenvironment. We evaluated the anti‐tumor and anti‐metastatic activities of SKI‐G‐801, a sma
Externí odkaz:
https://doaj.org/article/2810ccf729dc4cf68402dc5c21aa1ea6
Autor:
Seok-Young Kim, Ji Yeon Lee, Dong Hwi Kim, Hyeong -Seok Joo, Mi Ran Yun, Dongmin Jung, Jiyeon Yun, Seong Gu Heo, Beung -Chul Ahn, Chae Won Park, Kyoung Ho Pyo, You Jin Chun, Min Hee Hong, Hye Ryun Kim, Byoung Chul Cho
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Abstract Adequate preclinical model and model establishment procedure are required to accelerate translational research in lung cancer. We streamlined a protocol for establishing patient-derived cells (PDC) and identified effective targeted therapies
Externí odkaz:
https://doaj.org/article/a381d185621a4cc6965c977aa42e9fc1
Autor:
Sanghyun Lee, Chi-Hwan Choi, Mi-Ran Yun, Dae-Won Kim, Sung Soon Kim, Young Ki Choi, Young Sill Choi
Publikováno v:
Heliyon, Vol 7, Iss 10, Pp e08170- (2021)
To understand the origin of variants and their evolutionary history in the early stage of the COVID-19 pandemic, time-scaled phylogenetic and gene variation analyses were performed. The mutation patterns and evolution characteristics were examined us
Externí odkaz:
https://doaj.org/article/b9a1386c109940c2b5ea8ce460d2af2e
Autor:
Jang-Hoon Choi, Hye-Min Woo, Tae-Young Lee, So-Young Lee, Sang-Mu Shim, Woo-Jung Park, Jeong-Sun Yang, Joo Ae Kim, Mi-Ran Yun, Dae-Won Kim, Sung Soon Kim, Yi Zhang, Wei Shi, Lingshu Wang, Barney S Graham, John R Mascola, Nanshuang Wang, Jason S McLellan, Joo-Yeon Lee, Hansaem Lee
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232757 (2020)
Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe respiratory infection and continues to infect humans, thereby contributing to a high mortality rate (34.3% in 2019). In the absence of an available licensed vaccine and antiviral a
Externí odkaz:
https://doaj.org/article/0ff259c0cc9e41629a1adc7d5a531802
Autor:
Mi Ran Yun, Hun Mi Choi, You Won Lee, Hyeong Seok Joo, Chae Won Park, Jae Woo Choi, Dong Hwi Kim, Han Na Kang, Kyoung‐Ho Pyo, Eun Joo Shin, Hyo Sup Shim, Ross A Soo, James Chih‐Hsin Yang, Sung Sook Lee, Hyun Chang, Min Hwan Kim, Min Hee Hong, Hye Ryun Kim, Byoung Chul Cho
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 12, Pp n/a-n/a (2019)
Abstract Clinical benefit of ALK tyrosine kinase inhibitors (ALK‐TKIs) in ALK‐rearranged lung cancer has been limited by the inevitable development of acquired resistance, and bypass‐molecular resistance mechanisms remain poorly understood. We
Externí odkaz:
https://doaj.org/article/d4178ca591ff41c1b89ca89a0354a643
Autor:
Seung Yeon Oh, You Won Lee, Eun Ji Lee, Jae Hwan Kim, YoungJoon Park, Seong Gu Heo, Mi Ra Yu, Min Hee Hong, John DaSilva, Christopher Daly, Byoung Chul Cho, Sun Min Lim, Mi Ran Yun
Publikováno v:
Clinical Cancer Research. 29:221-232
Purpose: MET amplification is a frequent mechanism of resistance to EGFR tyrosine kinase inhibitors (TKI) in patients with EGFR-mutated non–small cell lung cancer (NSCLC), and combined treatment with EGFR TKIs and MET TKIs has been explored as a st