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Proteomic analysis of cardiorespiratory fitness for prediction of mortality and multisystem disease risks.

Autor: Perry AS; Vanderbilt Translational and Clinical Cardiovascular Research Center, Vanderbilt University School of Medicine, Nashville, TN, USA., Farber-Eger E; Vanderbilt Translational and Clinical Cardiovascular Research Center, Vanderbilt University School of Medicine, Nashville, TN, USA., Gonzales T; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK., Tanaka T; Longtidudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD, USA., Robbins JM; Cardiovascular Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA., Murthy VL; Department of Medicine, University of Michigan, Ann Arbor, MI, USA., Stolze LK; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA., Zhao S; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA., Huang S; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA., Colangelo LA; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Deng S; Cardiovascular Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA., Hou L; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Lloyd-Jones DM; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Walker KA; Multimodal Imaging of Neurodegenerative Disease (MIND) Unit, National Institute on Aging, NIH, Baltimore, MD, USA., Ferrucci L; Longtidudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD, USA., Watts EL; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA., Barber JL; Cardiovascular Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA., Rao P; Cardiovascular Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA., Mi MY; Cardiovascular Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA., Gabriel KP; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA., Hornikel B; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA., Sidney S; Kaiser Permanente, Oakland, CA, USA., Houstis N; Cardiology Division, Massachusetts General Hospital, Boston, MA, USA., Lewis GD; Cardiology Division, Massachusetts General Hospital, Boston, MA, USA., Liu GY; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of California Davis, Sacramento, CA, USA., Thyagarajan B; Department of Laboratory Medicine and Pathology, University of Minnesota, Minnesota, MN, USA., Khan SS; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Choi B; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Washko G; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Kalhan R; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Wareham N; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK., Bouchard C; Human Genomic Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA, USA., Sarzynski MA; Department of Exercise Science, University of South Carolina Columbia, Columbia, SC, USA., Gerszten RE; Cardiovascular Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA., Brage S; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK., Wells QS; Vanderbilt Translational and Clinical Cardiovascular Research Center, Vanderbilt University School of Medicine, Nashville, TN, USA., Nayor M; Sections of Cardiovascular Medicine and Preventive Medicine and Epidemiology, Department of Medicine, Boston University School of Medicine, Boston, MA, USA., Shah RV; Vanderbilt Translational and Clinical Cardiovascular Research Center, Vanderbilt University School of Medicine, Nashville, TN, USA. ravi.shah@vumc.org.

Publikováno v: Nature medicine [Nat Med] 2024 Jun; Vol. 30 (6), pp. 1711-1721. Date of Electronic Publication: 2024 Jun 04.

Omics-driven investigation of the biology underlying intrinsic submaximal working capacity and its trainability.

Autor: Hota M; Centre for Computational Biology, Duke-National University of Singapore Medical School, Singapore, Singapore., Barber JL; Department of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina, United States., Ruiz-Ramie JJ; Department of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina, United States.; Department of Kinesiology, Augusta University, Augusta, Georgia, United States., Schwartz CS; Department of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina, United States., Lam DTUH; Centre for Computational Biology, Duke-National University of Singapore Medical School, Singapore, Singapore., Rao P; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States., Mi MY; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States., Katz DH; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States., Robbins JM; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States., Clish CB; Metabolomics Platform, Broad Institute, Boston, Massachusetts, United States., Gerszten RE; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States., Sarzynski MA; Department of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina, United States., Ghosh S; Centre for Computational Biology, Duke-National University of Singapore Medical School, Singapore, Singapore.; Bioinformatics Section, Human Genomics Core, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States.; Program in Cardiovascular and Metabolic Disorders, Duke-National University of Singapore Medical School, Singapore, Singapore., Bouchard C; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States.

Publikováno v: Physiological genomics [Physiol Genomics] 2023 Nov 01; Vol. 55 (11), pp. 517-543. Date of Electronic Publication: 2023 Sep 04.

Associations between Metabolomic Biomarkers of Avocado Intake and Glycemia in the Multi-Ethnic Study of Atherosclerosis.

Autor: Wood AC; USDA/ARS Children's Nutrition Research Center, Baylor College of Medicine, Houston, TX, United States; Biomolecular Medicine, Section of Bioinformatics, Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom. Electronic address: LekkiWood@gmail.com., Goodarzi MO; Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, United States., Senn MK; USDA/ARS Children's Nutrition Research Center, Baylor College of Medicine, Houston, TX, United States; The University of Texas Health Science Center at Houston School of Public Health, Houston, TX, United States., Gadgil MD; Division of General Internal Medicine, Department of Medicine, University of California, San Francisco, CA, United States., Graca G; Section of Bioinformatics, Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom., Allison MA; Division of Preventive Medicine, Department of Family Medicine, University of California, San Diego, La Jolla, CA, United States., Tzoulaki I; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece; Department of Epidemiology and Biostatistics, Imperial College London School of Public Health, London, United Kingdom., Mi MY; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA, United States; Cardiovascular Institute, Beth Israel Deaconess Medical Center, Boston, MA, United States., Greenland P; Departments of Preventive Medicine and Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States., Ebbels T; Biomolecular Medicine, Section of Bioinformatics, Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom., Elliott P; Department of Epidemiology and Biostatistics, Imperial College London School of Public Health, London, United Kingdom; Laboratory for Clinical Biochemistry Research, University of Vermont, Burlington, VT, United States., Tracy RP; Laboratory for Clinical Biochemistry Research, University of Vermont, Burlington, VT, United States., Herrington DM; Section on Cardiovascular Medicine, Department of Internal Medicine, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC, United States., Rotter JI; Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-University of California, Los Angeles Medical Center, Torrance, CA, United States.

Publikováno v: The Journal of nutrition [J Nutr] 2023 Oct; Vol. 153 (10), pp. 2797-2807. Date of Electronic Publication: 2023 Aug 09.

Plasma Proteomic Risk Markers of Incident Type 2 Diabetes Reflect Physiologically Distinct Components of Glucose-Insulin Homeostasis.

Autor: Cronjé HT; Department of Public Health, Section of Epidemiology, University of Copenhagen, Copenhagen, Denmark., Mi MY; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA., Austin TR; Department of Epidemiology, University of Washington, Seattle, WA., Biggs ML; Department of Biostatistics, University of Washington, Seattle, WA., Siscovick DS; New York Academy of Medicine, New York, NY., Lemaitre RN; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA.; Department of Epidemiology, Health Systems and Population Health, University of Washington, Seattle, WA., Tracy RP; Department of Pathology Laboratory Medicine, Larner College of Medicine, University of Vermont, Burlington, VT., Djoussé L; Division of Aging, Brigham and Women's Hospital and Harvard Medical School, Boston, MA., Kizer JR; Cardiology Section San Francisco Veterans Affairs Health Care System, San Francisco, CA.; Department of Medicine, Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA., Ix JH; Division of Nephrology-Hypertension, University of California, San Diego, La Jolla, CA., Rao P; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA., Robbins JM; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA., Barber JL; Department of Exercise Science, University of South Carolina, Columbia, SC., Sarzynski MA; Department of Exercise Science, University of South Carolina, Columbia, SC., Clish CB; Broad Institute of MIT and Harvard, Cambridge, MA., Bouchard C; Pennington Biomedical Research Center, Baton Rouge, LA., Mukamal KJ; Division of General Medicine, Beth Israel Deaconess Medical Center, Boston, MA., Gerszten RE; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA., Jensen MK; Department of Public Health, Section of Epidemiology, University of Copenhagen, Copenhagen, Denmark.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.

Publikováno v: Diabetes [Diabetes] 2023 May 01; Vol. 72 (5), pp. 666-673.