Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Mi Hillefors"'
Publikováno v:
Pharmaceutical medicine. 34(4)
In 2012, the US National Institute of Mental Health launched three clinical trial contracts under a new FAST initiative. The overall goal for these contracts (Fast-Fail Trials) was to focus early-stage trials, testing novel pharmacologic agents that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc538d47f793eb1c398a96aea2d9ab5d
https://pubmed.ncbi.nlm.nih.gov/32705569
https://pubmed.ncbi.nlm.nih.gov/32705569
Autor:
Mi Hillefors
Publikováno v:
Neuropsychopharmacology. 43:1-76
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb3f7881955e6501257f7c12b8005b3f
https://doi.org/10.1038/s41386-018-0265-8
https://doi.org/10.1038/s41386-018-0265-8
Autor:
Matthew V. Rudorfer, Mi Hillefors
Publikováno v:
Pharmaceutical Medicine. 26:363-394
Throughout the phases of drug development, safety as well as efficacy measures are important to evaluate. Although it is well established that many types of medications that affect the central nervous system can influence emotional regulation and cog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40bbeaaed44ce7217a822580f3dde588
https://doi.org/10.1007/bf03262382
https://doi.org/10.1007/bf03262382
Publikováno v:
Cellular and Molecular Neurobiology. 27:701-716
(1) Axons contain numerous mRNAs and a local protein synthetic system that can be regulated independently of the cell body. (2) In this study, cultured primary sympathetic neurons were employed, to assess the effect of local protein synthesis blockad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::097836b799b0a38df73d92b58ab811f6
https://doi.org/10.1007/s10571-007-9148-y
https://doi.org/10.1007/s10571-007-9148-y
Autor:
Mi Hillefors, Gabriel von Euler
Publikováno v:
Neurochemistry International. 38:31-42
Dopamine D 3 receptors may be involved in drug addiction and in disorders such as schizophrenia and Parkinson’s disease. To determine the pharmacological properties of dopamine D 3 receptors in the rat caudate-putamen, we have investigated R (+)-[
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0151bf2a0a1239d2135de8a3ae2ce9c4
https://doi.org/10.1016/s0197-0186(00)00047-4
https://doi.org/10.1016/s0197-0186(00)00047-4
Autor:
Börje Bjelke, Mia von Euler, Therese M. Pham, Gabriel von Euler, Bengt G. Henriksson, Mi Hillefors
Publikováno v:
Experimental Neurology. 163:1-8
The organic solvent toluene is widely used in industry. The threshold limit value for extended occupational exposure to toluene is presently set to 200 ppm in the United States. We have investigated the effect of an inhalation exposure of 80 ppm for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f2d3600796c1f287f8308b47d06e91a
https://doi.org/10.1006/exnr.1999.7288
https://doi.org/10.1006/exnr.1999.7288
Publikováno v:
Biochemical Pharmacology. 58:1961-1964
To investigate if adenosine A 2A receptor stimulation in vivo modulates dopamine D 3 receptor binding, we analyzed the effects of 2-[ p -(carboxyethyl)-phenylethylamino]-5′- N -ethylcarboxyamidoadenosine (CGS 21680) on the binding properties of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ce1f08d848fd7db8de42d05d09905da
https://doi.org/10.1016/s0006-2952(99)00276-2
https://doi.org/10.1016/s0006-2952(99)00276-2
Publikováno v:
Brain Research. 822:126-131
We have analyzed the binding properties of the selective D 3 receptor agonist [ 3 H ]PD 128907 in 120 days old rats. In tissue sections, we found high numbers of binding sites for [ 3 H ]PD 128907 both in the islands of Calleja and the caudate–puta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c437d93592afbe335375cea8f35e34a
https://doi.org/10.1016/s0006-8993(99)01138-5
https://doi.org/10.1016/s0006-8993(99)01138-5
Publikováno v:
Toxicology. 100:185-194
Exposure to toluene (40-320 ppm; 4 weeks, 6 h/day, 5 days/week), followed by a postexposure period of 29-40 days, decreased the wet weight of the caudate-putamen and of the subcortical limbic area (maximal effect of 10% attained at 80 ppm toluene) of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10d7a3b36245af9818512e0be8047970
https://doi.org/10.1016/0300-483x(95)03084-s
https://doi.org/10.1016/0300-483x(95)03084-s
Publikováno v:
Results and Problems in Cell Differentiation ISBN: 9783642030185
Axons and presynaptic nerve terminals of both invertebrate and mam- malian SCG neurons contain a heterogeneous population of nuclear-encoded mito- chondrial mRNAs and a local cytosolic protein synthetic system. Nearly one quarter of the total protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9821be4c11100d0b346295e6651c9394
https://doi.org/10.1007/400_2009_1
https://doi.org/10.1007/400_2009_1
