Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mi Ae Jun"'
Autor:
Banda Narsaiah, Woul Seong Park, Sung-Soo Kim, Seung Kyu Kang, Jin Hee Ahn, Myung Ae Bae, Duck-Hyung Lee, Mi Sik Shin, Mi Ae Jun, Ki Young Kim, Hyae Gyeong Cheon, Sang Dal Rhee, Kwon Sung-Wook
Publikováno v:
Journal of Fluorine Chemistry. 130:1001-1010
A series of triazepane derivatives such as (R)-3-amino-1-(1,2,5-triazepan-1-yl)-4-(2,4,5-trifluorophenyl)butan-1-ones (7, 13a–p) and (R)-3-amino-1-(1,2,5-triazepan-5-yl)-4-(2,4,5-trifluorophenyl)butan-1-ones (17a–e) was synthesized and evaluated
Autor:
Sang Dal Rhee, Hyae Gyeong Cheon, Nam Sook Kang, Mi Sik Shin, Seung Kyu Kang, Jie Oh Lee, Jin Hee Ahn, Myung Ae Bae, Ki Young Kim, Woul Seong Park, Sung Gyu Kim, Sun Young Kim, Duck-Hyung Lee, Sung-Soo Kim, Sang Kwon Sohn, Mi Ae Jun, Kwang Rok Kim
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:6525-6529
Compounds with homopiperazine skeleton are designed to find a potent DPP-IV inhibitor without inhibiting CYP. Thus a series of β-aminoacyl-containing homopiperazine derivatives was synthesized and evaluated. Compounds with acid moiety were found to
Autor:
Sung-Soo Kim, Ki Young Kim, Woul Seong Park, Seung Kyu Kang, Mi Ae Jun, Jin Hee Ahn, Sang Dal Rhee, Mi Sik Shin, Duck-Hyung Lee, Hyae Gyeong Cheon
Publikováno v:
Bulletin of the Korean Chemical Society. 29:2129-2134
Department of Chemistry, Sogang University, Seoul 121-742, KoreaReceived August 3, 2008In continuation of our efforts to further derivatize dipeptidyl peptidase IV (DPP-IV) inhibitors, a series of β-aminoacyl-containing 5-, 6- and 7- membered cyclic
Autor:
Sun Ho Jung, Mi Ae Jun, Jie Oh Lee, Nam Sook Kang, Sung Gyu Kim, Sang-Kwon Sohn, Sun Young Kim, Seung Kyu Kang, Mi Sik Shin, Hyae Gyeong Cheon, Mi Sun Jin, Jin Hee Ahn, Sang Dal Rhee, Sung-Soo Kim, Kwang Rok Kim
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:2622-2628
Inhibitors of dipeptidyl peptidase IV (DPP-IV) have been shown to be effective treatments for type 2 diabetes. A series of β-aminoacyl-containing cyclic hydrazine derivatives were synthesized and evaluated as DPP-IV inhibitors. One member of this se
Autor:
Min-Sun Kim, Seung Kyu Kang, Jin Hee Ahn, Myung Ae Bae, Dong Hyun Song, Nam Sook Kang, Sang Dal Rhee, Mi Ae Jun, Kwang Rok Kim, Stephen Schneider, Woul Seong Park, Jie Oh Lee, Sung-Soo Kim, Peter Silinski, Ki-Young Kim, Sung-Eun Yoo, Mi Sik Shin
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(5)
A series of β-aminoacyl containing thiazolidine derivatives was synthesized and evaluated for their ability to inhibit DPP-IV. Several thiazolidine derivatives with an acid moiety were found to be potent DPP-IV inhibitors. Among them, compound 2da i
Autor:
Ki Young Kim, Woul Seong Park, Seung Kyu Kang, Sung-Soo Kim, Jin Hee Ahn, Mi Ae Jun, Sang Dal Rhee, Mi Sik Shin, Duck-Hyung Lee, Hyae Gyeong Cheon
Publikováno v:
ChemInform. 40
Department of Chemistry, Sogang University, Seoul 121-742, KoreaReceived August 3, 2008In continuation of our efforts to further derivatize dipeptidyl peptidase IV (DPP-IV) inhibitors, a series of β-aminoacyl-containing 5-, 6- and 7- membered cyclic
Autor:
Sung Gyu Kim, Seung Kyu Kang, Jin Hee Ahn, Myung Ae Bae, Mi Ae Jun, Kwang Rok Kim, Sang-Kwon Sohn, Duck-Hyung Lee, Sung-Soo Kim, Hyae Gyeong Cheon, Woul Seong Park, Ki Young Kim, Sang Dal Rhee, Nam Sook Kang, Jie Oh Lee
Publikováno v:
European journal of medicinal chemistry. 43(9)
A series of pyrazoline derivatives with beta-amino acyl group were synthesized and evaluated for their ability to inhibit dipeptidyl peptidase IV. Several pyrazoline derivatives exhibited submicromolar inhibitory activities against DPP-IV. X-ray co-c