Zobrazeno 1 - 10
of 187
pro vyhledávání: '"Mi‐Ock Lee"'
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 2, Pp 615-630 (2024)
Abstract Background Fat infiltration in muscle, called ‘myosteatosis’, precedes muscle atrophy, which subsequently results in sarcopenia. Myosteatosis is frequently observed in patients with nonalcoholic fatty liver disease (NAFLD). We have previ
Externí odkaz:
https://doaj.org/article/b442553b3f8e4254a04a307a2aceb60d
Autor:
Sungmin Pak, Hyunil Ryu, Sujin Lim, Thien-Luan Nguyen, Sungwook Yang, Sumin Kang, Yeon Gyu Yu, Junhyuk Woo, Chanjin Kim, Cristina Fenollar-Ferrer, John N. Wood, Mi-Ock Lee, Gyu-Sang Hong, Kyungreem Han, Tae Song Kim, Uhtaek Oh
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114334- (2024)
Summary: Mechanically activating (MA) channels transduce numerous physiological functions. Tentonin 3/TMEM150C (TTN3) confers MA currents with slow inactivation kinetics in somato- and barosensory neurons. However, questions were raised about its rol
Externí odkaz:
https://doaj.org/article/24c1e3aeacd941c0a941fb4c98cf0b97
Publikováno v:
Hepatology Communications, Vol 5, Iss 12, Pp 2121-2138 (2021)
Lysosomes are intracellular acidic organelles with catabolic functions that contribute to the activation of autophagy. Although autophagy abnormality is associated with defects in lysosomal acidification during the progression of nonalcoholic fatty l
Externí odkaz:
https://doaj.org/article/50f230311ab34304a7a6483c380a92df
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-8 (2019)
Abstract Background Nuclear receptor subfamily 1, group D, member 1 (NR1D1) is a ligand-regulated nuclear receptor and transcriptional factor. Although recent studies have implicated NR1D1 as a regulator of DNA repair and proliferation in breast canc
Externí odkaz:
https://doaj.org/article/091ba504857242d2b9f6cae27e52fe69
Autor:
Yong-Hyun Han, Hyeon-Ji Kim, Hyelin Na, Min-Woo Nam, Ju-Yeon Kim, Jun-Seok Kim, Seung-Hoi Koo, Mi-Ock Lee
Publikováno v:
Cell Reports, Vol 20, Iss 1, Pp 124-135 (2017)
The regulation of M1/M2 polarization in liver macrophages is closely associated with the progression of nonalcoholic steatohepatitis (NASH); however, the mechanism involved in this process remains unclear. Here, we describe the orphan nuclear recepto
Externí odkaz:
https://doaj.org/article/0bbd9f18edfa4014b44b344957215e5d
Autor:
Jin-Sil Park, Su-Jin Moon, Mi-Ae Lim, Jae-Kyeong Byun, Sun-Hee Hwang, SeungCheon Yang, Eun-Kyung Kim, Hohyun Lee, Sung-Min Kim, Jennifer Lee, Seung-Ki Kwok, Jun-Ki Min, Mi-Ock Lee, Dong-Yun Shin, Sung-Hwan Park, Mi-La Cho
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Rheumatoid arthritis (RA) is a chronic inflammatory polyarthritis characterized by progressive joint destruction. IL-17-producing CD4+ T (Th17) cells play pivotal roles in RA development and progression. Retinoic acid receptor-related orphan receptor
Externí odkaz:
https://doaj.org/article/09734b9d410f417f80267afbadda250d
Autor:
Yunwon Moon, Su Mi Choi, Soojeong Chang, Bongju Park, Seongyeol Lee, Mi-Ock Lee, Hueng-Sik Choi, Hyunsung Park
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130911 (2015)
This study evaluated HIF-1α inhibitors under different hypoxic conditions, physiological hypoxia (5% O2) and severe hypoxia (0.1% O2). We found that chenodeoxy cholic acid (CDCA) reduced the amount of HIF-1α protein only under physiological hypoxia
Externí odkaz:
https://doaj.org/article/1cf4372dfb534fee8fbf15e75c888069
Autor:
Ja Hee Lee, Eun-Jin Kim, Don-Kyu Kim, Ji-Min Lee, Seung Bum Park, In-Kyu Lee, Robert A Harris, Mi-Ock Lee, Hueng-Sik Choi
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46324 (2012)
Multiple cellular signaling pathways that control metabolism and survival are activated when cell are incubated under hypoxic conditions. Activation of the hypoxia inducible factor (HIF)-1 promotes expression of genes that increase the capacity to co
Externí odkaz:
https://doaj.org/article/a110d7abfb5c496dadb89d59f098fd05
Publikováno v:
Biomolecules & Therapeutics. 30:391-398
Polyploidization is a process by which cells are induced to possess more than two sets of chromosomes. Although polyploidization is not frequent in mammals, it is closely associated with development and differentiation of specific tissues and organs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b936e509525ba1f2637bc7650c54cc82
https://doi.org/10.4062/biomolther.2022.070
https://doi.org/10.4062/biomolther.2022.070
Autor:
Ga Young Lim, Sun Wook Cho, Na‐Lee Ka, Kyung‐Hun Lee, Seock‐Ah Im, Seung‐Su Kim, Sewon Hwang, Mi‐Ock Lee
Publikováno v:
Journal of Cellular Physiology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e51229e13087cab4a076d7ca0e3e5376
https://doi.org/10.1002/jcp.31022
https://doi.org/10.1002/jcp.31022