Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mišo Mitkovski"'
Autor:
Dilja Krueger-Burg, Daniela Winkler, Mišo Mitkovski, Fernanda Daher, Anja Ronnenberg, Oliver Marcus Schlüter, Ekrem Dere, Hannelore Ehrenreich
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 10 (2016)
Impairments in social skills are central to mental disease, and developing tools for their assessment in mouse models is essential. Here we present the SocioBox, a new behavioral paradigm to measure social recognition memory. Using this paradigm, we
Externí odkaz:
https://doaj.org/article/7e4a82030f5a47cab2f4774439714802
Autor:
Fernando Aprile-Garcia, Michael W Metzger, Marcelo Paez-Pereda, Herbert Stadler, Matías Acuña, Ana C Liberman, Sergio A Senin, Juan Gerez, Esteban Hoijman, Damian Refojo, Mišo Mitkovski, Markus Panhuysen, Walter Stühmer, Florian Holsboer, Jan M Deussing, Eduardo Arzt
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151862 (2016)
The P2X7 receptor is a member of the P2X family of ligand-gated ion channels. A single-nucleotide polymorphism leading to a glutamine (Gln) by arginine (Arg) substitution at codon 460 of the purinergic P2X7 receptor (P2X7R) has been associated with m
Externí odkaz:
https://doaj.org/article/c7a2c0f6da22409e92bac38cbfde733e
Autor:
Zoltán Pethő, Karolina Najder, Stephanie Beel, Benedikt Fels, Ilka Neumann, Sandra Schimmelpfennig, Sarah Sargin, Maria Wolters, Klavs Grantins, Eva Wardelmann, Miso Mitkovski, Andrea Oeckinghaus, Albrecht Schwab
Publikováno v:
JCI Insight, Vol 8, Iss 19 (2023)
Pancreatic ductal adenocarcinoma (PDAC) progresses in an organ with a unique pH landscape, where the stroma acidifies after each meal. We hypothesized that disrupting this pH landscape during PDAC progression triggers pancreatic stellate cells (PSCs)
Externí odkaz:
https://doaj.org/article/917ef2c5c0ad45b0bfab8102214a7f29
Autor:
Marcio, Lazzarini, Sabine, Martin, Mišo, Mitkovski, Rita Raisman, Vozari, Walter, Stühmer, Elaine Del, Bel
Publikováno v:
Glia. 61(7)
Neuron-glia interactions play a key role in maintaining and regulating the central nervous system. Glial cells are implicated in the function of dopamine neurons and regulate their survival and resistance to injury. Parkinson's disease is characteriz
Autor:
Jan Seidel, Fabian Bockhop, Miso Mitkovski, Sabine Martin, Anja Ronnenberg, Dilja Krueger‐Burg, Katharina Schneider, Heiko Röhse, Liane Wüstefeld, Filippo Cosi, Kai Bröking, Annekathrin Schacht, Hannelore Ehrenreich
Publikováno v:
FASEB BioAdvances, Vol 2, Iss 1, Pp 18-32 (2020)
Abstract To assess complex social recognition in mice, we previously developed the SocioBox paradigm. Unexpectedly, 4 weeks after performing in the SocioBox, mice displayed robust social avoidance during Y‐maze sociability testing. This unique “s
Externí odkaz:
https://doaj.org/article/70d611d9ef034762879269f48514dcf1
Autor:
Christine Silvia Gibhardt, Sabrina Cappello, Rajesh Bhardwaj, Romana Schober, Sonja Agnes Kirsch, Zuriñe Bonilla del Rio, Stefan Gahbauer, Anna Bochicchio, Magdalena Sumanska, Christian Ickes, Ioana Stejerean-Todoran, Miso Mitkovski, Dalia Alansary, Xin Zhang, Aram Revazian, Marc Fahrner, Victoria Lunz, Irene Frischauf, Ting Luo, Daria Ezerina, Joris Messens, Vsevolod Vadimovich Belousov, Markus Hoth, Rainer Arnold Böckmann, Matthias Albrecht Hediger, Rainer Schindl, Ivan Bogeski
Publikováno v:
Cell Reports, Vol 33, Iss 3, Pp 108292- (2020)
Summary: Store-operated calcium entry (SOCE) through STIM-gated ORAI channels governs vital cellular functions. In this context, SOCE controls cellular redox signaling and is itself regulated by redox modifications. However, the molecular mechanisms
Externí odkaz:
https://doaj.org/article/9aa210ab347a4829a53ce714c6a1e9f1
Autor:
Fernanda Ramos-Gomes, Julia Bode, Alyona Sukhanova, Svetlana V. Bozrova, Mara Saccomano, Miso Mitkovski, Julia Eva Krueger, Anja K. Wege, Walter Stuehmer, Pavel S. Samokhvalov, Daniel Baty, Patrick Chames, Igor Nabiev, Frauke Alves
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract Early detection of malignant tumours and, especially, micrometastases and disseminated tumour cells is still a challenge. In order to implement highly sensitive diagnostic tools we demonstrate the use of nanoprobes engineered from nanobodies
Externí odkaz:
https://doaj.org/article/31f241baea3d44148c2b495267e0f415
Autor:
Mariza Bortolanza, Roberta Cavalcanti-Kiwiatkoski, Fernando E. Padovan-Neto, Célia Aparecida da-Silva, Miso Mitkovski, Rita Raisman-Vozari, Elaine Del-Bel
Publikováno v:
Neurobiology of Disease, Vol 73, Iss , Pp 377-387 (2015)
l-3, 4-dihydroxyphenylalanine (l-DOPA) is the most effective treatment for Parkinson's disease but can induce debilitating abnormal involuntary movements (dyskinesia). Here we show that the development of l-DOPA-induced dyskinesia in the rat is accom
Externí odkaz:
https://doaj.org/article/4165fa7cbf8241aab150b99de11b0d0b
Autor:
M Andrea Markus, Christian Dullin, Miso Mitkovski, Eva Prieschl-Grassauer, Michelle M Epstein, Frauke Alves
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e90017 (2014)
BackgroundMolecular imaging of lung diseases, including asthma, is limited and either invasive or non-specific. Central to the inflammatory process in asthma is the recruitment of eosinophils to the airways, which release proteases and proinflammator
Externí odkaz:
https://doaj.org/article/b1d66c9732f54d6da4343751eb1ac54c