Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Mi, Gu"'
The US FDA's Project Optimus initiative that emphasizes dose optimization prior to marketing approval represents a pivotal shift in oncology drug development. It has a ripple effect for rethinking what changes may be made to conventional pivotal tria
Externí odkaz:
http://arxiv.org/abs/2406.00196
The Project Optimus initiative by the FDA's Oncology Center of Excellence is widely viewed as a groundbreaking effort to change the $\textit{status quo}$ of conventional dose-finding strategies in oncology. Unlike in other therapeutic areas where mul
Externí odkaz:
http://arxiv.org/abs/2304.06164
Publikováno v:
Zhongguo quanke yixue, Vol 27, Iss 09, Pp 1028-1033 (2024)
Food intake disorders are costly to treat, with an increasing prevalence over the years, and a higher risk of mortality compared to other psychiatric disorders. Avoidant/restrictive food intake disorder (ARFID) , as a relatively new type of food inta
Externí odkaz:
https://doaj.org/article/3312334c0aac44fe87dd806e4fc84a8a
Autor:
Yong-Qing Zhang, Hyun Kyu Min, Eunchong Hong, Eunhye Yu, Sun Mi Gu, Seong Shoon Yoon, Dohyun Lee, Jaejun Lee, Jin Tae Hong, Jaesuk Yun
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 169, Iss , Pp 115860- (2023)
Intracranial self-stimulation (ICSS) of the medial forebrain bundle in mice is an experimental model use to assess the relative potential of reward-seeking behaviors. Here, we used the ICSS model to evaluate the abuse potential of 18 abused drugs: 3-
Externí odkaz:
https://doaj.org/article/c4583dac162145e68b46a6544316685b
Autor:
Eunhye Yu, Yunjeong Song, Sun Mi Gu, Yang Hee Jo, Sang Won Yeon, Kyu Jin Han, Mi Kyeong Lee, Jung Kee Min, Jaesuk Yun
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Age-related macular degeneration (AMD) is a major cause of vision loss in the elderly population. Anti-vascular endothelial growth factor (VEGF) antibody therapy is applicable to neovascularisation of AMD; however, the prevention of fibrosis
Externí odkaz:
https://doaj.org/article/0a98b216220c4097828dd256f26eea15
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 160, Iss , Pp 114318- (2023)
Ketamine is a widely used anesthetic with N-methyl-D-aspartate (NMDA) receptor antagonism. Exposure to ketamine and NMDA receptor antagonists may induce psychosis. However, the mechanism underlying the effects of ketamine on the immature brain remain
Externí odkaz:
https://doaj.org/article/1f737d07e2c642d284b85f76925a72a8
Autor:
Sun Mi Gu, Eunchong Hong, Sowoon Seo, Sanghyeon Kim, Seong Shoon Yoon, Hye Jin Cha, Jaesuk Yun
Publikováno v:
Journal of Veterinary Science; Sep2024, Vol. 25 Issue 5, p1-12, 12p
Autor:
Herbst, Roy S., Arkenau, Hendrik Tobias, Bendell, Johanna, Arrowsmith, Edward, Wermke, Martin, Soriano, Andres, Penel, Nicolas, Santana-Davila, Rafael, Bischoff, Helge, Chau, Ian, Mi, Gu, Wang, Hong, Rasmussen, Erik, Ferry, David, Chao, Bo H., Paz-Ares, Luis
Publikováno v:
In Journal of Thoracic Oncology February 2021 16(2):289-298
Autor:
Herbst, Roy S, Arkenau, Hendrik-Tobias, Santana-Davila, Rafael, Calvo, Emiliano, Paz-Ares, Luis, Cassier, Philippe A, Bendell, Johanna, Penel, Nicolas, Krebs, Matthew G, Martin-Liberal, Juan, Isambert, Nicolas, Soriano, Andres, Wermke, Martin, Cultrera, Jennifer, Gao, Ling, Widau, Ryan C, Mi, Gu, Jin, Jin, Ferry, David, Fuchs, Charles S, Petrylak, Daniel P, Chau, Ian
Publikováno v:
In The Lancet Oncology August 2019 20(8):1109-1123
Autor:
Zhang, Yan-Qiong, Shen, Yan, Liao, Ming-Mei, Mao, Xia, Mi, Gu-Jie, You, Chen, Guo, Qiu-Yan, Li, Wei-Jie, Wang, Xiao-Yue, Lin, Na, Webster, Thomas J.
Publikováno v:
In Nanomedicine: Nanotechnology, Biology, and Medicine January 2019 15(1):86-97