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Autor:
Hany A. Omar, Noura Khaiwa, Taleb H. Al-Tel, Gorka Orive, Noor R. Maarouf, Anusha Sebastian, Mhd H. Darwish, Mohamad Hamad, Dima W. Alhamad
Publikováno v:
European Journal of Medicinal Chemistry. 223:113639
Nature represents a rich source of compounds used for the treatment of many diseases. Camptothecin (CPT), isolated from the bark of Camptotheca acuminata, is a cytotoxic alkaloid that attenuates cancer cell replication by inhibiting DNA topoisomerase