Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Mhairi K Sigrist"'
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e65372 (2013)
Cross-sectional studies in dialysis demonstrate muscle wasting associated with loss of function, increased morbidity and mortality. The relative drivers are poorly understood. There is a paucity of data regarding interval change in muscle in pre-dial
Externí odkaz:
https://doaj.org/article/5b980a3d2f4e4d689d4f3342e5a9e264
Autor:
Natasha Kekre, Kevin A. Hay, John R. Webb, Ranjeeta Mallick, Miruna Balasundaram, Mhairi K. Sigrist, Anne-Marie Clement, Julie S. Nielsen, Jennifer Quizi, Eric Yung, Scott D. Brown, Lisa Dreolini, Daniel D. Waller, Julian Smazynski, Nicole S. Gierc, Bianca C. Loveless, Kayla Clark, Tyler Dyer, Richard Hogg, Leah McCormick, Michael Gignac, Shanti Bell, D. Maria Chapman, David Bond, Siao Yong, Rachel Fung, Heather M. Lockyer, Victoria Hodgson, Catherine Murphy, Ana Subramanian, Evelyn Wiebe, Piriya Yoganathan, Liana Medynski, Dominique C. Vaillan, Alice Black, Sheryl McDiarmid, Michael Kennah, Linda Hamelin, Kevin Song, Sujaatha Narayanan, Judith A. Rodrigo, Stefany Dupont, Terry Hawrysh, Justin Presseau, Kednapa Thavorn, Manoj M. Lalu, Dean A. Fergusson, John C. Bell, Harold Atkins, Brad H. Nelson, Robert A. Holt
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Access to commercial CD19 CAR-T cells remains limited even in wealthy countries like Canada due to clinical, logistical, and financial barriers related to centrally manufactured products. We created a non-commercial academic platform for end-to-end m
Externí odkaz:
https://doaj.org/article/ba9bb5ccb69a4646aee78f29aa8e0137
Autor:
Adeera Levin, Mila Tang, Monica Beaulieu, Ognjenka Djurdjev, Paul Taylor, Alexandra Romann, Mhairi K. Sigrist, G. Chiarelli, Suneet Singh
Publikováno v:
Clinical Nephrology. 78:254-262
OBJECTIVE Vascular stiffness is prevalent in end-stage renal disease patients and predicts adverse events. This study describes the prevalence of vascular stiffness and its associated factors in a cohort of incident peritoneal dialysis (PD) patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ca9e5bad8c6323fea272349d0319dc
https://doi.org/10.5414/cn107398
https://doi.org/10.5414/cn107398
Publikováno v:
Nephron Extra
Nephron Extra, Vol 1, Iss 1, Pp 190-200 (2011)
Nephron Extra, Vol 1, Iss 1, Pp 190-200 (2011)
Background/Aims: The ideal hemoglobin target in chronic kidney disease remains unknown. Ultimately, individualized targets may depend upon the properties of the patient’s endothelial and vascular milieu, and thus the complex relationships between t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03fd01bdc5d90adf0457423a2e41258d
http://europepmc.org/articles/PMC3290845
http://europepmc.org/articles/PMC3290845
Autor:
Philipp Kümpers, Helen J. Jefferies, Hermann Haller, Jan T. Kielstein, Mhairi K. Sigrist, Sascha David, Christopher W. McIntyre, Stephen G. John
Publikováno v:
Nephrology Dialysis Transplantation. 27:1867-1872
Background. The pathophysiology of aggravated atherosclerosis in chronic kidney disease (CKD) is still incompletely understood. However, there is an increasing focus on non-traditional risk factors, including endothelial dysfunction. Angiopoietin-2 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac1a44605030a0aca2a0ba1b7b58b6e
https://doi.org/10.1093/ndt/gfr551
https://doi.org/10.1093/ndt/gfr551
Autor:
Christopher W. McIntyre, Paul J. Owen, Mhairi K. Sigrist, James O. Burton, Mohamed Tarek Eldehni, Stephen G. John, Philip Kam-Tao Li, Cheuk-Chun Szeto, Shvan Korsheed, Ka-Bik Lai, Laura E. A. Harrison, Helen J. Jefferies, Daljit Hothi
Publikováno v:
Clinical Journal of the American Society of Nephrology. 6:133-141
Summary Background and objectives Translocated endotoxin derived from intestinal bacteria has a wide range of adverse effects on cardiovascular (CV) structure and function, driving systemic inflammation, atherosclerosis and oxidative stress. This stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034bba485c571e969a4373312f5e8cd0
https://doi.org/10.2215/cjn.04610510
https://doi.org/10.2215/cjn.04610510
Autor:
Elliott Chum, Adeera Levin, William A. Gourlay, Ada W.Y. Chung, Genevieve Brin, Jong Moo Kim, H.H. Clarice Yang, Mhairi K. Sigrist
Publikováno v:
Nephrology Dialysis Transplantation. 25:4031-4041
Background. Abnormalities of vascular function and accumulation of oxidative stress have been associated with chronic kidney disease (CKD). Dialysis modalities, peritoneal dialysis (PD) and haemodialysis (HD) may differentially impact on vascular fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a59284121564d5f29ce81b3488f8b258
https://doi.org/10.1093/ndt/gfq202
https://doi.org/10.1093/ndt/gfq202
Autor:
Elliott Chum, Anthony D. Booth, Adeera Levin, Ada W.Y. Chung, H.H. Clarice Yang, Mhairi K. Sigrist, William A. Gourlay
Publikováno v:
Journal of Vascular Research. 47:128-138
We hypothesized that there was differential vasomotor dysfunction in the microcirculation between nondialyzed and dialyzed chronic kidney disease (CKD) patients. During live donor kidney transplantation procedures, skin arterioles (SkA; internal diam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9698c27512b70996345c267c03795857
https://doi.org/10.1159/000235967
https://doi.org/10.1159/000235967
Publikováno v:
Nephrology Dialysis Transplantation. 25:187-191
Background. Pyrophosphate (PPi) is a potent inhibitor of vascular calcification and may be deficient in renal failure. We sought to determine whether plasma PPi is affected by dialysis or the mode of dialysis and whether it correlates with vascular c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93e11e64eb6d0f878a72f46a2348ce20
https://doi.org/10.1093/ndt/gfp362
https://doi.org/10.1093/ndt/gfp362
Autor:
Stephen G. John, Christopher W. McIntyre, William S. Priestman, Lindsay J. Chesterton, Paul J. Owen, Mhairi K. Sigrist, Stewart H. Lambie
Publikováno v:
Hemodialysis International. 13:293-300
Dialysis-induced hypotension remains a significant problem in hemodialysis (HD) patients. Numerous factors result in dysregulation of blood pressure control and impaired myocardial reserve in response to HD-induced cardiovascular stress. Episodic int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0844449ba9edfe8569fcef1908d942e5
https://doi.org/10.1111/j.1542-4758.2009.00365.x
https://doi.org/10.1111/j.1542-4758.2009.00365.x