Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Mfn, mitofusin"'
Autor:
Milana Fraiberg, Boris Macek, Zvulun Elazar, Philipp J. Kahle, Anna Lechado Terradas, Katharina Zittlau
Publikováno v:
The Journal of Biological Chemistry
The journal of biological chemistry 297(5), 101339 (2021). doi:10.1016/j.jbc.2021.101339
The journal of biological chemistry 297(5), 101339 (2021). doi:10.1016/j.jbc.2021.101339
Mitochondria are important organelles in eukaryotes. Turnover and quality control of mitochondria are regulated at the transcriptional and posttranslational level by several cellular mechanisms. Removal of defective mitochondrial proteins is mediated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fbec8d603702bfc18179f4f97b4c81b
http://europepmc.org/articles/PMC8591368
http://europepmc.org/articles/PMC8591368
Autor:
Hani N. Sabbah
Publikováno v:
JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 5, Iss 1, Pp 88-106 (2020)
JACC: Basic to Translational Science, Vol 5, Iss 1, Pp 88-106 (2020)
Visual Abstract
Highlights • Cardiac energy deprivation due to mitochondrial dysfunction is characteristic of heart failure. • Mitochondrial dysfunction contributes to worsening of the heart failure state. • Pharmacologic targeting of mito
Highlights • Cardiac energy deprivation due to mitochondrial dysfunction is characteristic of heart failure. • Mitochondrial dysfunction contributes to worsening of the heart failure state. • Pharmacologic targeting of mito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7bf223c5fc74d0943fdde83a16b2755
http://europepmc.org/articles/PMC7000886
http://europepmc.org/articles/PMC7000886
Publikováno v:
Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences, Vol 28, Iss 12, Pp 6957-6962 (2021)
Saudi Journal of Biological Sciences, Vol 28, Iss 12, Pp 6957-6962 (2021)
Graphical abstract
Asthma is a complicated lung disease, which has increased morbidity and mortality rates in worldwide. There is an overlap between asthma pathophysiology and mitochondrial dysfunction and MSCs may have regulatory effect on mito
Asthma is a complicated lung disease, which has increased morbidity and mortality rates in worldwide. There is an overlap between asthma pathophysiology and mitochondrial dysfunction and MSCs may have regulatory effect on mito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d570e737062499ca4ded98c542acd9
https://pubmed.ncbi.nlm.nih.gov/34866995
https://pubmed.ncbi.nlm.nih.gov/34866995
Publikováno v:
Biochemical Pharmacology
Graphical abstract
Mitochondria have been recognized as ancient bacteria that contain evolutionary endosymbionts. Metabolic pathways and inflammatory signals interact within mitochondria in response to different stresses, such as viral infection
Mitochondria have been recognized as ancient bacteria that contain evolutionary endosymbionts. Metabolic pathways and inflammatory signals interact within mitochondria in response to different stresses, such as viral infection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ddc4d9d42601f3845bf94ae189aa4cb
https://doi.org/10.1016/j.bcp.2018.08.044
https://doi.org/10.1016/j.bcp.2018.08.044
Autor:
Jeffrey A. Medin, Teruyuki Yanagisawa, Ryosuke Nomura, Shigeki Kushimoto, Takeya Sato, Yuka Sato
Publikováno v:
Redox Biology, Vol 13, Iss C, Pp 407-417 (2017)
Redox Biology
Redox Biology
Highly active anti-retrovirus therapy (HAART) has been used to block the progression and symptoms of human immunodeficiency virus infection. Although it decreases morbidity and mortality, clinical use of HAART has also been linked to various adverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199ff92ea316bbfc7f473293f4473e56
https://doi.org/10.1016/j.redox.2017.06.011
https://doi.org/10.1016/j.redox.2017.06.011
Autor:
Natalie Qishan Zhang, YT Cheung, Sally Shuk Yee Cheng, S Wuwongse, Simon Ming-Yuen Lee, Yuen Shan Ho, Raymond Chuen-Chung Chang, Clara Hiu-Ling Hung
Publikováno v:
Redox Biology
Redox Biology, Vol 14, Iss, Pp 7-19 (2018)
Redox Biology, Vol 14, Iss, Pp 7-19 (2018)
Mitochondrial fragmentation due to fission/fusion imbalance has often been linked to mitochondrial dysfunction and apoptosis in neurodegeneration. Conventionally, it is believed that once mitochondrial morphology shifts away from its physiological tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a205e68f781dbfdb7f84839a1ce8b1
http://europepmc.org/articles/PMC5567977
http://europepmc.org/articles/PMC5567977
Autor:
Lee A. Denson
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 2, Pp 426-427 (2020)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Mitochondria exist in a constantly remodelling network, and excessive fragmentation can be pathophysiological. Mitochondrial dysfunction can accompany enteric inflammation, but any contribution of altered mitochondrial dynamics (ie,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bfbc0a62ca07f7cce53f7ceaf2eb4e9
http://www.sciencedirect.com/science/article/pii/S2352345X20300849
http://www.sciencedirect.com/science/article/pii/S2352345X20300849
Autor:
Andrew R. Hall, Marthe H.R. Ludtmann, Marianne T. Neary, Ross A. Breckenridge, Keat Eng Ng, Sang Bing Ong, Timothy J. Mohun, Andrey Y. Abramov, Izabela Piotrowska, Derek J. Hausenloy
Publikováno v:
Journal of Molecular and Cellular Cardiology
Fetal cardiomyocyte adaptation to low levels of oxygen in utero is incompletely understood, and is of interest as hypoxia tolerance is lost after birth, leading to vulnerability of adult cardiomyocytes. It is known that cardiac mitochondrial morpholo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b033589c3c5844920026fd6d1a6db636
https://pubmed.ncbi.nlm.nih.gov/24984146
https://pubmed.ncbi.nlm.nih.gov/24984146
Autor:
David A. Jans, Ivan Hong Wee Ng, Mark A. Febbraio, Esther J. H. Boey, Darren C. Henstridge, MengJie Hu, Yuekang Xu, Marie A. Bogoyevitch, Simon Crawford
Publikováno v:
Biochemical Journal
p32 [also known as HABP1 (hyaluronan-binding protein 1), gC1qR (receptor for globular head domains complement 1q) or C1qbp (complement 1q-binding protein)] has been shown previously to have both mitochondrial and non-mitochondrial localization and fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a446bf8770389164e0468b076d175f8
https://pubmed.ncbi.nlm.nih.gov/23692256
https://pubmed.ncbi.nlm.nih.gov/23692256
Autor:
Sudarsanareddy Lokireddy, Craig McFarlane, Isuru Wijerupage Wijesoma, Sabeera Bonala, Ravi Kambadur, Mridula Sharma, Siu Kwan Sze, Meng Wei
Publikováno v:
Biochemical Journal
Humoral and tumoral factors collectively promote cancer-induced skeletal muscle wasting by increasing protein degradation. Although several humoral proteins, namely TNFα (tumour necrosis factor α) and IL (interleukin)-6, have been shown to induce s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d83ca336ccaced8597b4c0bcb4ef20b9
https://pubmed.ncbi.nlm.nih.gov/27060107
https://pubmed.ncbi.nlm.nih.gov/27060107