Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mff, Mitochondrial fission factor"'
Autor:
Wing-Kee Lee, Michelle Maaß, Amy Quach, Nataliya Poscic, Holly Prangley, Erin-Claire Pallott, Jiyoon L. Kim, Jason S. Pierce, Besim Ogretmen, Anthony H. Futerman, Frank Thévenod
Publikováno v:
The Journal of Biological Chemistry
Oncogenic multidrug resistance (MDR) is commonly intrinsic to renal cancer based on the physiological expression of detoxification transporters, particularly ABCB1, thus hampering chemotherapy. ABCB1 activity is directly dependent on its lipid microe
Autor:
Milana Fraiberg, Boris Macek, Zvulun Elazar, Philipp J. Kahle, Anna Lechado Terradas, Katharina Zittlau
Publikováno v:
The Journal of Biological Chemistry
The journal of biological chemistry 297(5), 101339 (2021). doi:10.1016/j.jbc.2021.101339
The journal of biological chemistry 297(5), 101339 (2021). doi:10.1016/j.jbc.2021.101339
Mitochondria are important organelles in eukaryotes. Turnover and quality control of mitochondria are regulated at the transcriptional and posttranslational level by several cellular mechanisms. Removal of defective mitochondrial proteins is mediated
Autor:
Luis F. Godinho, Celien Lismont, Ruth E. Carmichael, Marc Fransen, Peter Freisinger, Christian Hacker, Markus Islinger, Yunhong Wang, Michael Schrader, Sacha Ferdinandusse, Josiah B. Passmore, David M. Richards, Tina A. Schrader
Publikováno v:
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 1867(7):118709. Elsevier
Biochimica et Biophysica Acta. Molecular Cell Research
Biochimica et Biophysica Acta. Molecular Cell Research
Peroxisomes are highly dynamic subcellular compartments with important functions in lipid and ROS metabolism. Impaired peroxisomal function can lead to severe metabolic disorders with developmental defects and neurological abnormalities. Recently, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71618f64ddde7c5bfa06a81ad78908a
Autor:
Ruth E. Carmichael, Laura DiGiovanni, Michael Schrader, Peter K. Kim, Rechal Kumar, Beatriz S.C. Silva
Publikováno v:
Biochim Biophys Acta Mol Cell Res
Biochimica et Biophysica Acta. Molecular Cell Research
Biochimica et Biophysica Acta. Molecular Cell Research
Membrane-bound organelles in eukaryotic cells form an interactive network to coordinate and facilitate cellular functions. The formation of close contacts, termed “membrane contact sites” (MCSs), represents an intriguing strategy for organelle in
Publikováno v:
Redox Biology, Vol 16, Iss, Pp 303-313 (2018)
Redox Biology
Redox Biology
The accumulation of uremic toxins in chronic kidney disease (CKD) induces inflammation, oxidative stress and endothelial dysfunction, which is a key step in atherosclerosis. Accumulating evidence indicates increased mitochondrial fission is a contrib
Autor:
Jeffrey A. Medin, Teruyuki Yanagisawa, Ryosuke Nomura, Shigeki Kushimoto, Takeya Sato, Yuka Sato
Publikováno v:
Redox Biology, Vol 13, Iss C, Pp 407-417 (2017)
Redox Biology
Redox Biology
Highly active anti-retrovirus therapy (HAART) has been used to block the progression and symptoms of human immunodeficiency virus infection. Although it decreases morbidity and mortality, clinical use of HAART has also been linked to various adverse
Autor:
Natalie Qishan Zhang, YT Cheung, Sally Shuk Yee Cheng, S Wuwongse, Simon Ming-Yuen Lee, Yuen Shan Ho, Raymond Chuen-Chung Chang, Clara Hiu-Ling Hung
Publikováno v:
Redox Biology
Redox Biology, Vol 14, Iss, Pp 7-19 (2018)
Redox Biology, Vol 14, Iss, Pp 7-19 (2018)
Mitochondrial fragmentation due to fission/fusion imbalance has often been linked to mitochondrial dysfunction and apoptosis in neurodegeneration. Conventionally, it is believed that once mitochondrial morphology shifts away from its physiological tu
Autor:
Celia Bañuls, Noelia Diaz-Morales, Susana Rovira-Llopis, Victor M. Victor, Milagros Rocha, Antonio Hernández-Mijares
Publikováno v:
Redox Biology, Vol 11, Iss, Pp 637-645 (2017)
Redox Biology
Redox Biology
Mitochondria play a key role in maintaining cellular metabolic homeostasis. These organelles have a high plasticity and are involved in dynamic processes such as mitochondrial fusion and fission, mitophagy and mitochondrial biogenesis. Type 2 diabete
Autor:
Michel Jadot, Guillaume Van Beersel, Thierry Arnould, Stéphane Demine, Isabelle Hamer, Eliane Tihon
Publikováno v:
Bioscience Reports
Bioscience Reports, Vol 33, Iss 2, p e00023 (2013)
Van Beersel, G, Tihon, E, Demine, S, Hamer, I, Jadot, M & Arnould, T 2013, ' Different molecular mechanisms involved in spontaneous and oxidative stress-induced mitochondrial fragmentation in tripeptidyl peptidase-1 (TPP-1)-deficient fibroblasts ', Bioscience reports, vol. 33, no. 2, pp. 243-258 . https://doi.org/10.1042/BSR20120104
Bioscience Reports, Vol 33, Iss 2, p e00023 (2013)
Van Beersel, G, Tihon, E, Demine, S, Hamer, I, Jadot, M & Arnould, T 2013, ' Different molecular mechanisms involved in spontaneous and oxidative stress-induced mitochondrial fragmentation in tripeptidyl peptidase-1 (TPP-1)-deficient fibroblasts ', Bioscience reports, vol. 33, no. 2, pp. 243-258 . https://doi.org/10.1042/BSR20120104
NCLs (neuronal ceroid lipofuscinoses) form a group of eight inherited autosomal recessive diseases characterized by the intralysosomal accumulation of autofluorescent pigments, called ceroids. Recent data suggest that the pathogenesis of NCL is assoc