Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Mezida B. Saeed"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Actin cytoskeletal dynamics drive cellular shape changes, linking numerous cell functions to physiological and pathological cues. Mutations in actin regulators that are differentially expressed or enriched in immune cells cause severe human diseases
Externí odkaz:
https://doaj.org/article/1f242bb5f87740e790628cded1662c7c
Autor:
Joanna S. Kritikou, Mariana M.S. Oliveira, Julien Record, Mezida B. Saeed, Saket M. Nigam, Minghui He, Marton Keszei, Arnika K. Wagner, Hanna Brauner, Anton Sendel, Saikiran K. Sedimbi, Stamatina Rentouli, David P. Lane, Scott B. Snapper, Klas Kärre, Peter Vandenberghe, Jordan S. Orange, Lisa S. Westerberg
Publikováno v:
JCI Insight, Vol 6, Iss 6 (2021)
X-linked neutropenia (XLN) is caused by gain-of-function mutations in the actin regulator Wiskott-Aldrich Syndrome protein (WASp). XLN patients have reduced numbers of cytotoxic cells in peripheral blood; however, their capacity to kill tumor cells r
Externí odkaz:
https://doaj.org/article/c629a13a387342b6b4e5b5c45a493ae0
Autor:
Jérôme Mastio, Mezida B. Saeed, Hannah Wurzer, Max Krecke, Lisa S. Westerberg, Clément Thomas
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Congenital defects of the immune system called primary immunodeficiency disorders (PID) describe a group of diseases characterized by a decrease, an absence, or a malfunction of at least one part of the immune system. As a result, PID patients are mo
Externí odkaz:
https://doaj.org/article/99592bf8e5324e7f844b48103c560886
Autor:
Laurent Schmied, Thuy T. Luu, Jonas N. Søndergaard, Sophia H. Hald, Stephan Meinke, Dara K. Mohammad, Sunitha B. Singh, Corinna Mayer, Giovanna Perinetti Casoni, Michael Chrobok, Heinrich Schlums, Giorgia Rota, Hieu M. Truong, Lisa S. Westerberg, Greta Guarda, Evren Alici, Arnika K. Wagner, Nadir Kadri, Yenan T. Bryceson, Mezida B. Saeed, Petter Höglund
Publikováno v:
Science Signaling. 16
Natural killer (NK) cells recognize virally infected cells and tumors. NK cell function depends on balanced signaling from activating receptors, recognizing products from tumors or viruses, and inhibitory receptors (such as KIR/Ly49), which recognize
Autor:
Laurent Schmied, Thuy T. Luu, Jonas N. Søndergaard, Stephan Meinke, Dara K. Mohammad, Sunitha B. Singh, Corinna Mayer, Giovanna P. Casoni, Michael Chrobok, Heinrich Schlums, Giorgia Rota, Hieu M. Truong, Lisa S. Westerberg, Greta Guarda, Evren Alici, Arnika K. Wagner, Nadir Kadri, Yenan T. Bryceson, Mezida B. Saeed, Petter Höglund
Signaling via inhibitory KIR/Ly49 receptors preserves natural killer (NK) cell self-tolerance but also conveys NK cell reactivity towards MHC class-I low target cells in an education process. Here, we demonstrate that mouse NK cell education by H-2Dd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bee51cff1904bfe834a5903c3c74a94
https://doi.org/10.1101/2022.03.08.483415
https://doi.org/10.1101/2022.03.08.483415
Autor:
E.A. Deordieva, Lieselot Buedts, Lisa S. Westerberg, Chaohong Liu, Roberta D’Aulerio, Julien Record, Mezida B. Saeed, Peter Vandenberghe, Siobhan O. Burns, Lennart Hammarström, Marton Keszei, Larissa Vasconcelos-Fontes, Yu Xia, Chiara Geyer, Mariana M.S. Oliveira, Charlotte Cunningham-Rundles, Anna Shcherbina, Minghui He, Vinicius Cotta-de-Almeida, Lia Gonçalves Pinho, Lena Bohaumilitzky, Meike Thiemann, Dmitry Pershin, Rhaissa Vieira, Joao Pedro Lopes, Xiaodong Zhao, Adrian J. Thrasher
BACKGROUND: B-cell affinity maturation in germinal center relies on regulated actin dynamics for cell migration and cell-to-cell communication. Activating mutations in the cytoskeletal regulator Wiskott-Aldrich syndrome protein (WASp) cause X-linked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0ef37ac865c60929f5c0a816547960f
https://lirias.kuleuven.be/handle/123456789/680651
https://lirias.kuleuven.be/handle/123456789/680651
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Actin cytoskeletal dynamics drive cellular shape changes, linking numerous cell functions to physiological and pathological cues. Mutations in actin regulators that are differentially expressed or enriched in immune cells cause severe human diseases
Autor:
Mezida B. Saeed, Marton Keszei, Peter Vandenberghe, David P. Lane, Anton Sendel, Scott B. Snapper, Saket M. Nigam, Arnika Kathleen Wagner, Mariana M.S. Oliveira, Saikiran K. Sedimbi, Joanna S. Kritikou, Minghui He, Lisa S. Westerberg, Klas Kärre, Hanna Brauner, Julien Record, Jordan S. Orange, Stamatina Rentouli
Publikováno v:
JCI Insight, Vol 6, Iss 6 (2021)
JCI Insight
JCI Insight
X-linked neutropenia (XLN) is caused by gain-of-function mutations in the actin regulator Wiskott-Aldrich Syndrome protein (WASp). XLN patients have reduced numbers of cytotoxic cells in peripheral blood; however, their capacity to kill tumor cells r
Autor:
Mezida B. Saeed, Jérôme Mastio, Lisa S. Westerberg, Max Krecke, Clément Thomas, Hannah Wurzer
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology
Congenital defects of the immune system called primary immunodeficiency disorders (PID) describe a group of diseases characterized by a decrease, an absence, or a malfunction of at least one part of the immune system. As a result, PID patients are mo
Publikováno v:
International review of cell and molecular biology. 356
Actin cytoskeleton remodeling facilitates and fine-tunes diverse cellular processes. Cells have evolved to use the same building blocks of actin monomers to form filaments through the sequential and synchronous use of actin filament regulators. This