Short-term effects of dapagliflozin on maximal functional capacity in heart failure with reduced ejection fraction (DAPA-VO2): a randomized clinical trial

Autor: Palau, P, Amiguet, M, Dominguez, E, Sastre, C, Mollar, A, Seller, J, Pinilla, JMG, Larumbe, A, Valle, A, Doblas, JJG, de la Espriella, R, Minana, G, Mezcua, AR, Santas, E, Bodi, V, Sanchis, J, Pascual-Figal, D, Gorriz, JL, Bayes-Genis, A, Nunez, J

Publikováno v: EUROPEAN JOURNAL OF HEART FAILURE
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
Consejo Superior de Investigaciones Científicas (CSIC)
r-FISABIO. Repositorio Institucional de Producción Científica
instname
European Journal of Heart Failure
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol

AIMS: This study aimed to evaluate the effect of dapagliflozin on 1 and 3-month maximal functional capacity in patients with stable heart failure with reduced ejection fraction (HFrEF). METHODS AND RESULTS: In this multicentre, randomized, double-bli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::306106af88a8b6c5887d9232657c3dc8
https://www.fundanet.incliva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=16599

Emery-Dreifuss muscular dystrophy Type 1 is associated with a high risk of malignant ventricular arrhythmias and end-stage heart failure.

Autor: Cannie DE; Institute of Cardiovascular Science, University College London, London, UK.; Department of Inherited Cardiovascular Diseases, Barts Heart Centre, St Bartholomew's Hospital, London, UK., Syrris P; Institute of Cardiovascular Science, University College London, London, UK.; Department of Inherited Cardiovascular Diseases, Barts Heart Centre, St Bartholomew's Hospital, London, UK., Protonotarios A; Institute of Cardiovascular Science, University College London, London, UK.; Department of Inherited Cardiovascular Diseases, Barts Heart Centre, St Bartholomew's Hospital, London, UK., Bakalakos A; Institute of Cardiovascular Science, University College London, London, UK.; Department of Inherited Cardiovascular Diseases, Barts Heart Centre, St Bartholomew's Hospital, London, UK., Pruny JF; APHP, Sorbonne Université, Centre de Référence pour les Maladies Cardiaques Héréditaires ou rares, ICAN Institute, Hôpital Pitié-Salpêtrière, Paris, France., Ditaranto R; Cardiology Unit, Cardiac Thoracic and Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN-GUARDHEART)., Martinez-Veira C; Unidad de Cardiopatías Familiares, Complexo Hospitalario Universitario de A Coruña, Instituto de Investigación Biomédica de A Coruña (INIBIC/CIBERCV), Servizo Galego de Saúde (SERGAS), Universidade da Coruña, A Coruña, Spain., Larrañaga-Moreira JM; Unidad de Cardiopatías Familiares, Complexo Hospitalario Universitario de A Coruña, Instituto de Investigación Biomédica de A Coruña (INIBIC/CIBERCV), Servizo Galego de Saúde (SERGAS), Universidade da Coruña, A Coruña, Spain., Medo K; Cardiovascular Institute and Adult Medical Genetics Program, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Bermúdez-Jiménez FJ; Cardiology Department, Hospital Universitario Virgen de las Nieves, Instituto de Investigación Biosanitaria IBS Granada, Granada, Spain., Ben Yaou R; APHP-Sorbonne Universite, Centre de Référence des Maladies Neuromusculaires, Inserm, Centre de Recherche en Myologie, Institut de Myologie, Hopital Pitie-Salpetriere, Paris, France., Leturcq F; APHP, Cochin Hospital, Department of Genomic Medicine and Systemic Diseases, University of Paris, Paris, France., Mezcua AR; Heart Failure and Familial Cardiomyopathies Unit, Department of Cardiology, IBIMA, Málaga.  Spain.; Ciber-Cardiovascular, Instituto de Salud Carlos III, Madrid, Spain., Marini-Bettolo C; Department of Cardiology, Newcastle upon Tyne Hospitals NHS Trust, Newcastle upon Tyne, UK.; The John Walton Muscular Dystrophy Research Centre, Translational and Clinical Research Institute, Newcastle University and Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom., Cabrera E; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN-GUARDHEART).; Heart Failure and Inherited Cardiac Diseases Unit, Department of Cardiology, Hospital Universitario Puerta de Hierro, IDIPHISA, CIBERCV, Madrid, Spain., Reuter C; Stanford Center for Inherited Cardiovascular Disease, Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, 291 Campus Drive, Stanford, CA 94305, USA., Limeres Freire J; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN-GUARDHEART).; Ciber-Cardiovascular, Instituto de Salud Carlos III, Madrid, Spain.; Inherited Cardiovascular Diseases Unit, Department of Cardiology, Hospital Universitari Vall d´Hebron, Vall d'Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain., Rodríguez-Palomares JF; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN-GUARDHEART).; Ciber-Cardiovascular, Instituto de Salud Carlos III, Madrid, Spain.; Inherited Cardiovascular Diseases Unit, Department of Cardiology, Hospital Universitari Vall d´Hebron, Vall d'Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain., Mestroni L; Cardiovascular Institute and Adult Medical Genetics Program, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Taylor MRG; Cardiovascular Institute and Adult Medical Genetics Program, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Parikh VN; Stanford Center for Inherited Cardiovascular Disease, Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, 291 Campus Drive, Stanford, CA 94305, USA., Ashley EA; Stanford Center for Inherited Cardiovascular Disease, Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, 291 Campus Drive, Stanford, CA 94305, USA., Barriales-Villa R; Unidad de Cardiopatías Familiares, Complexo Hospitalario Universitario de A Coruña, Instituto de Investigación Biomédica de A Coruña (INIBIC/CIBERCV), Servizo Galego de Saúde (SERGAS), Universidade da Coruña, A Coruña, Spain., Jiménez-Jáimez J; Cardiology Department, Hospital Universitario Virgen de las Nieves, Instituto de Investigación Biosanitaria IBS Granada, Granada, Spain., Garcia-Pavia P; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN-GUARDHEART).; Heart Failure and Inherited Cardiac Diseases Unit, Department of Cardiology, Hospital Universitario Puerta de Hierro, IDIPHISA, CIBERCV, Madrid, Spain.; Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain., Charron P; APHP, Sorbonne Université, Centre de Référence pour les Maladies Cardiaques Héréditaires ou rares, ICAN Institute, Hôpital Pitié-Salpêtrière, Paris, France.; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN-GUARDHEART)., Biagini E; Cardiology Unit, Cardiac Thoracic and Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN-GUARDHEART)., García Pinilla JM; Heart Failure and Familial Cardiomyopathies Unit, Department of Cardiology, IBIMA, Málaga.  Spain.; Ciber-Cardiovascular, Instituto de Salud Carlos III, Madrid, Spain.; Departamento de Medicina y Dermatología, Universidad de Malaga, Malaga, Spain., Bourke J; Department of Cardiology, Newcastle upon Tyne Hospitals NHS Trust, Newcastle upon Tyne, UK.; The John Walton Muscular Dystrophy Research Centre, Translational and Clinical Research Institute, Newcastle University and Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom., Savvatis K; Institute of Cardiovascular Science, University College London, London, UK.; Department of Inherited Cardiovascular Diseases, Barts Heart Centre, St Bartholomew's Hospital, London, UK.; William Harvey Institute, Queen Mary University London, London, United Kingdom.; National Institute for Health Research, University College London Hospitals Biomedical Research Centre, London, United Kingdom., Wahbi K; AP-HP, Pitié-Salpêtrière Hospital, Reference Center for Muscle Diseases Paris-Est, Myology Institute, Paris, France.; AP-HP, Cochin Hospital, Cardiology Department, Paris Cedex, France.; Université de Paris, Paris, France; Paris Cardiovascular Research Center (PARCC), INSERM Unit 970, Paris, France., Elliott PM; Institute of Cardiovascular Science, University College London, London, UK.; Department of Inherited Cardiovascular Diseases, Barts Heart Centre, St Bartholomew's Hospital, London, UK.

Publikováno v: European heart journal [Eur Heart J] 2023 Dec 21; Vol. 44 (48), pp. 5064-5073.