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Safety and efficacy of a COVID-19 treatment with nebulized and/or intravenous neutral electrolyzed saline combined with usual medical care vs. usual medical care alone: A randomized, open-label, controlled trial.

Autor: Delgado-Enciso I; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México., Paz-Garcia J; Department of Internal Medicine and Surgery, Union Hospital Center, Villa de Álvarez, Colima 28970, México., Barajas-Saucedo CE; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Mokay-Ramírez KA; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Meza-Robles C; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México., Lopez-Flores R; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México., Delgado-Machuca M; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México., Murillo-Zamora E; Department of Research, General Hospital of Zone No. 1 and Family Medicine Unit No. 19 IMSS, Villa de Alvarez, Colima 28984, México., Toscano-Velazquez JA; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Delgado-Enciso J; Department of Research, Foundation for Cancer Ethics, Education and Research of the Cancerology State Institute, Colima 28085, México., Melnikov V; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Walle-Guillen M; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México., Galvan-Salazar HR; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México., Delgado-Enciso OG; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.; Department of Research, Foundation for Cancer Ethics, Education and Research of the Cancerology State Institute, Colima 28085, México., Cabrera-Licona A; Department of Research, Esteripharma S.A. de C.V., Ciudad de México 03100, México., Danielewicz-Mata EJ; COVID-19 Respiratory Care Clinic INSABI Poliforum, Tuxtla Gutierrez, Chiapas 29040, México., Mandujano-Diaz PJ; COVID-19 Respiratory Care Clinic INSABI Poliforum, Tuxtla Gutierrez, Chiapas 29040, México., Guzman-Esquivel J; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.; Department of Research, Foundation for Cancer Ethics, Education and Research of the Cancerology State Institute, Colima 28085, México., Montes-Galindo DA; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México., Perez-Martinez H; COVID-19 Respiratory Care Clinic INSABI Poliforum, Tuxtla Gutierrez, Chiapas 29040, México., Jimenez-Villegaz JM; COVID-19 Respiratory Care Clinic INSABI Poliforum, Tuxtla Gutierrez, Chiapas 29040, México., Hernandez-Rangel AE; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Montes-Diaz P; Private Medical Office Xochitepec, Xochitepec, Morelos 62795, México., Rodriguez-Sanchez IP; Laboratory of Molecular and Structural Physiology, School of Biological Sciences, Universidad Autónoma de Nuevo León, San Nicolas de los Garza, Nuevo León 66455, México., Martinez-Fierro ML; Molecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas 98160, México., Garza-Veloz I; Molecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas 98160, México., Tiburcio-Jimenez D; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Zaizar-Fregoso SA; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Gonzalez-Alcaraz F; COVID-19 Respiratory Care Clinic INSABI Poliforum, Tuxtla Gutierrez, Chiapas 29040, México., Gutierrez-Gutierrez L; COVID-19 Respiratory Care Clinic INSABI Poliforum, Tuxtla Gutierrez, Chiapas 29040, México., Diaz-Lopez L; COVID-19 Respiratory Care Clinic INSABI Poliforum, Tuxtla Gutierrez, Chiapas 29040, México., Ramirez-Flores M; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Guzman-Solorzano HP; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Gaytan-Sandoval G; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México., Martinez-Perez CR; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México., Espinoza-Gómez F; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Rojas-Larios F; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Hirsch-Meillon MJ; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México., Baltazar-Rodriguez LM; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Barrios-Navarro E; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Oviedo-Rodriguez V; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México., Mendoza-Hernandez MA; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Prieto-Diaz-Chavez E; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Paz-Michel BA; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.; Department of Research, Esteripharma S.A. de C.V., Ciudad de México 03100, México.

Publikováno v: Experimental and therapeutic medicine [Exp Ther Med] 2021 Sep; Vol. 22 (3), pp. 915. Date of Electronic Publication: 2021 Jun 29.