Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Meyer, Felix B."'
Autor:
Meyer, Felix B.1 (AUTHOR), Goebel, Sophie1 (AUTHOR), Spangel, Sonja B.1 (AUTHOR), Leovsky, Christiane1 (AUTHOR), Hoelzer, Doerte1 (AUTHOR), Thierbach, René1 (AUTHOR) rene.thierbach@uni-jena.de
Publikováno v:
BMC Cancer. 5/27/2021, Vol. 21 Issue 1, p1-14. 14p.
Autor:
Marx, Christian, Sonnemann, Jürgen, Beyer, Mandy, Maddocks, Oliver D.K., Lilla, Sergio, Hauzenberger, Irene, Piée‐Staffa, Andrea, Siniuk, Kanstantsin, Nunna, Suneetha, Marx‐Blümel, Lisa, Westermann, Martin, Wagner, Tobias, Meyer, Felix B., Thierbach, René, Mullins, Christina S., Kdimati, Said, Linnebacher, Michael, Neri, Francesco, Heinzel, Thorsten, Wang, Zhao‐Qi, Krämer, Oliver H.
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 15, Iss 12, Pp 3404-3429 (2021)
Molecular Oncology, Vol 15, Iss 12, Pp 3404-3429 (2021)
Late‐stage colorectal cancer (CRC) is still a clinically challenging problem. The activity of the tumor suppressor p53 is regulated via post‐translational modifications (PTMs). While the relevance of p53 C‐terminal acetylation for transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cde0064ce3798f2f8b20b7b4eb3317f4
https://eprints.gla.ac.uk/248531/1/248531.pdf
https://eprints.gla.ac.uk/248531/1/248531.pdf
Akademický článek
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Autor:
Marx, Christian, Schaarschmidt, Marc U., Kirkpatrick, Joanna, Marx-Blümel, Lisa, Halilovic, Melisa, Westermann, Martin, Doerte Hoelzer, Meyer, Felix B., Yibo Geng, Buder, Katrin, Schadwinkel, Hauke M., Siniuk, Kanstantsin, Becker, Sabine, Thierbach, René, Beck, James F., Sonnemann, Jürgen, Wang, Zhao-Qi
Additional file 6: Figure S6. Accumulation of intracellular defects in WE-68 cells. WE-68 cells were treated with 45 nM AUY922 (B), 2 µM VE821 (C) and their combination (D). DMSO was used for control (A). Intracellular structures were analyzed by tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dcc21f19002189b210076416ad61cfd
Autor:
Marx, Christian, Schaarschmidt, Marc U., Kirkpatrick, Joanna, Marx-Blümel, Lisa, Halilovic, Melisa, Westermann, Martin, Doerte Hoelzer, Meyer, Felix B., Yibo Geng, Buder, Katrin, Schadwinkel, Hauke M., Siniuk, Kanstantsin, Becker, Sabine, Thierbach, René, Beck, James F., Sonnemann, Jürgen, Wang, Zhao-Qi
Additional file 4: Figure S4. Analysis of molecular alterations. (A) Otherwise isogenic p53 wild-type (wt) and p53 null (p53-/-) HCT116 cells were treated with 45 nM AUY922 ± 2 µM VE821 for 24 h. Analysis of indicated proteins was done by Western b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cbc98543869a4c5aa68a62ec86f0a49
Autor:
Marx, Christian, Schaarschmidt, Marc U., Kirkpatrick, Joanna, Marx-Blümel, Lisa, Halilovic, Melisa, Westermann, Martin, Doerte Hoelzer, Meyer, Felix B., Yibo Geng, Buder, Katrin, Schadwinkel, Hauke M., Siniuk, Kanstantsin, Becker, Sabine, Thierbach, René, Beck, James F., Sonnemann, Jürgen, Wang, Zhao-Qi
Additional file 3: Figure S3: Analysis of cell cycle distribution. (A) WE-68 and (B) A673 cells were treated with 15–45 nM of AUY922, 2 µM of VE821, 5 µM of KU55933 and their combinations for 24 h. (C-E) WE-68 and A673 cells were treated with ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d30bab0885736de5acf2d479d4b64c04
Autor:
Marx, Christian, Schaarschmidt, Marc U., Kirkpatrick, Joanna, Marx-Blümel, Lisa, Halilovic, Melisa, Westermann, Martin, Doerte Hoelzer, Meyer, Felix B., Yibo Geng, Buder, Katrin, Schadwinkel, Hauke M., Siniuk, Kanstantsin, Becker, Sabine, Thierbach, René, Beck, James F., Sonnemann, Jürgen, Wang, Zhao-Qi
Additional file 7: Figure S7. Accumulation of intracellular defects in A673 cells. A673 cells were treated with 45 nM AUY922 (B), 2 µM VE821 (C) and their combination (D). DMSO was used for control (A). Intracellular structures were analyzed by tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3774262af5971ef87832c04dd9828f32
Autor:
Marx, Christian, Schaarschmidt, Marc U., Kirkpatrick, Joanna, Marx-Blümel, Lisa, Halilovic, Melisa, Westermann, Martin, Doerte Hoelzer, Meyer, Felix B., Yibo Geng, Buder, Katrin, Schadwinkel, Hauke M., Siniuk, Kanstantsin, Becker, Sabine, Thierbach, René, Beck, James F., Sonnemann, Jürgen, Wang, Zhao-Qi
Additional file 10: Figure S10. Ingenuity pathway analysis of the proteome data set. A673 cells were treated with 45 nM AUY922 ± 2 µM VE821 for 24 h, and a quantitative whole proteome analysis was done by mass spectrometry from three individual exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf9dab9c57a378e957068e0532b6345e
Autor:
Marx, Christian, Schaarschmidt, Marc U., Kirkpatrick, Joanna, Marx-Blümel, Lisa, Halilovic, Melisa, Westermann, Martin, Doerte Hoelzer, Meyer, Felix B., Yibo Geng, Buder, Katrin, Schadwinkel, Hauke M., Siniuk, Kanstantsin, Becker, Sabine, Thierbach, René, Beck, James F., Sonnemann, Jürgen, Wang, Zhao-Qi
Additional file 5: Figure S5. Analysis of ER stress. WE-68 and A673 cells were treated with 15–45 nM of AUY922, 2 µM of VE821, 5 µM of KU55933 and their combinations for 24 h. (A) Intracellular reactive oxygen species (ROS) level were analyzed by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::094c36417ad348be8a1f5850c7e2ae4c
Autor:
Meyer, Felix B., Goebel, Sophie, Spangel, Sonja B., Leovsky, Christiane, Hoelzer, Doerte, Thierbach, René
Additional file 1: Supplementary Figure 1. Densitometric analysis of Western Blot results exemplary shown in Fig. 1b. Data are shown as mean + standard error of 3 independent experiments, normalized to α-Tubulin and shown relatively to the 24 h cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042fb0ede762193c73d2c99f0bdd44aa