Identification of a new aggressive axis driven by ciliogenesis and absence of VDAC1-ΔC in clear cell Renal Cell Carcinoma patients

Autor: Mazure, Nathalie M, Fabbri, Lucilla, Dufies, Maeva, Lacas-Gervais, Sandra, Gardie, Betty, Gad-Lapiteau, Sophie, Parola, Julien, Nottet, Nicolas, Meyenberg Cunha de Padua, Monique, Contenti, Julie, Borchiellini, Delphine, Ferrero, Jean-Marc, Leclercq, Nathalie Rioux, Ambrosetti, Damien, Mograbi, Baharia, Richard, Stéphane, Viotti, Julien, Chamorey, Emmanuel, Sadaghianloo, Nirvana, Rouleau, Matthieu, Craigen, William, Mari, Bernard, Clavel, Stéphan, Pagès, Gilles, Pouysségur, Jacques, Bost, Frédéric, Mazure, Nathalie

Publikováno v: Theranostics
Theranostics, Ivyspring International Publisher, 2020, 10 (6), pp.2696-2713. ⟨10.7150/thno.41001⟩
Theranostics, 2020, 10 (6), pp.2696-2713. ⟨10.7150/thno.41001⟩

International audience; Rationale: Renal cell carcinoma (RCC) accounts for about 2% of all adult cancers, and clear cell RCC (ccRCC) is the most common RCC histologic subtype. A hallmark of ccRCC is the loss of the primary cilium, a cellular antenna

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f9c43ef1acea5eae482c94bbff7a383
https://hal.archives-ouvertes.fr/hal-03034269

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Hypoxia protects against the cell death triggered by oxovanadium–galactomannan complexes in HepG2 cells

Autor: Meyenberg Cunha-de Padua, Monique, Noleto, Guilhermina Rodrigues, de Oliveira Petkowicz, Carmen Lucia, Cadena, Silvia Maria Suter Correia, Bost, Frédéric, Pouysségur, Jacques, Mazure, Nathalie M.

Publikováno v: Cellular and Molecular Biology Letters
Cellular and Molecular Biology Letters, Springer Verlag (Germany), 2019, 24, ⟨10.1186/s11658-019-0135-3⟩
Cellular & Molecular Biology Letters
Cellular & Molecular Biology Letters, Vol 24, Iss 1, Pp 1-11 (2019)

International audience; Background: Polysaccharides from various sources have been used in traditional medicine for centuries. The beneficial pharmacological effects of plant-derived polysaccharides include anti-tumor activity. Methods: Here, we eval

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::259233266488b6589c0e68735efa3409
https://hal.archives-ouvertes.fr/hal-03034381/document

Identification of a new aggressive axis driven by ciliogenesis and absence of VDAC1-ΔC in clear cell Renal Cell Carcinoma patients.

Autor: Fabbri L; Université Côte d'Azur (UCA), CNRS-UMR 7284-Inserm U1081, IRCAN, Centre Antoine Lacassagne, 33 Ave. de Valombrose, 06189 Nice, France.; Present address: Université Côte d'Azur (UCA), INSERM U1065, C3M, 151 Route de St Antoine de Ginestière, BP2 3194, 06204 Nice Cedex 03, France., Dufies M; Medical Biology Department, Centre Scientifique de Monaco (CSM), Monaco., Lacas-Gervais S; Université Côte d'Azur (UCA), Centre Commun de Microscopie Appliquée, Nice, France., Gardie B; Institut du thorax, INSERM, CNRS, Univ. Nantes, Nantes, France., Gad-Lapiteau S; INSERM UMR 1186, Integrative Tumor Immunology and Genetic Oncology, Gustave Roussy, EPHE, PSL, Fac. de médecine - Univ. Paris-Sud, Université Paris-Saclay, 114 rue Edouard Vaillant, 94800 Villejuif, France., Parola J; Université Côte d'Azur (UCA), CNRS-UMR 7284-Inserm U1081, IRCAN, Centre Antoine Lacassagne, 33 Ave. de Valombrose, 06189 Nice, France.; Centre Antoine Lacassagne, Oncology Department, Nice, France., Nottet N; Present address: Université Côte d'Azur (UCA), INSERM U1065, C3M, 151 Route de St Antoine de Ginestière, BP2 3194, 06204 Nice Cedex 03, France., Meyenberg Cunha de Padua M; Present address: Université Côte d'Azur (UCA), INSERM U1065, C3M, 151 Route de St Antoine de Ginestière, BP2 3194, 06204 Nice Cedex 03, France., Contenti J; Present address: Université Côte d'Azur (UCA), INSERM U1065, C3M, 151 Route de St Antoine de Ginestière, BP2 3194, 06204 Nice Cedex 03, France., Borchiellini D; Centre Antoine Lacassagne, Oncology Department, Nice, France., Ferrero JM; Present address: Université Côte d'Azur (UCA), INSERM U1065, C3M, 151 Route de St Antoine de Ginestière, BP2 3194, 06204 Nice Cedex 03, France.; Centre Antoine Lacassagne, Oncology Department, Nice, France., Leclercq NR; Rennes University, Rennes University Hospital, Department of Pathology, Rennes, France., Ambrosetti D; Centre Hospitalier Universitaire de Nice, Department of Pathology, Nice, France., Mograbi B; Université Côte d'Azur (UCA), CNRS-UMR 7284-Inserm U1081, IRCAN, Centre Antoine Lacassagne, 33 Ave. de Valombrose, 06189 Nice, France., Richard S; INSERM UMR 1186, Integrative Tumor Immunology and Genetic Oncology, Gustave Roussy, EPHE, PSL, Fac. de médecine - Univ. Paris-Sud, Université Paris-Saclay, 114 rue Edouard Vaillant, 94800 Villejuif, France.; REDIR Center, Department of Urology, AP-HP, Bicêtre Hospital, 78 Rue du Général Leclerc, 94270 Le Kremlin-Bicêtre., Viotti J; Centre Antoine Lacassagne, Statistics Department, Nice, France., Chamorey E; Centre Antoine Lacassagne, Statistics Department, Nice, France., Sadaghianloo N; Université Côte d'Azur (UCA), CNRS-UMR 7284-Inserm U1081, IRCAN, Centre Antoine Lacassagne, 33 Ave. de Valombrose, 06189 Nice, France.; Present address: Université Côte d'Azur (UCA), INSERM U1065, C3M, 151 Route de St Antoine de Ginestière, BP2 3194, 06204 Nice Cedex 03, France.; Centre Hospitalier Universitaire de Nice, Department of Vascular Surgery, Nice, France., Rouleau M; Université Côte d'Azur (UCA), CNRS-UMR 7370, LP2M, Nice, France., Craigen WJ; Department of Molecular and Human Genetics, The Mitochondrial Diagnostic Laboratory, Baylor College of Medicine, Houston, TX 77030, USA., Mari B; Université Côte d'Azur (UCA), CNRS, IPMC, FHUOncoAge, 06560 Valbonne, France., Clavel S; Present address: Université Côte d'Azur (UCA), INSERM U1065, C3M, 151 Route de St Antoine de Ginestière, BP2 3194, 06204 Nice Cedex 03, France., Pagès G; Université Côte d'Azur (UCA), CNRS-UMR 7284-Inserm U1081, IRCAN, Centre Antoine Lacassagne, 33 Ave. de Valombrose, 06189 Nice, France.; Medical Biology Department, Centre Scientifique de Monaco (CSM), Monaco., Pouysségur J; Université Côte d'Azur (UCA), CNRS-UMR 7284-Inserm U1081, IRCAN, Centre Antoine Lacassagne, 33 Ave. de Valombrose, 06189 Nice, France.; Medical Biology Department, Centre Scientifique de Monaco (CSM), Monaco., Bost F; Present address: Université Côte d'Azur (UCA), INSERM U1065, C3M, 151 Route de St Antoine de Ginestière, BP2 3194, 06204 Nice Cedex 03, France., Mazure NM; Université Côte d'Azur (UCA), CNRS-UMR 7284-Inserm U1081, IRCAN, Centre Antoine Lacassagne, 33 Ave. de Valombrose, 06189 Nice, France.; Present address: Université Côte d'Azur (UCA), INSERM U1065, C3M, 151 Route de St Antoine de Ginestière, BP2 3194, 06204 Nice Cedex 03, France.

Publikováno v: Theranostics [Theranostics] 2020 Feb 03; Vol. 10 (6), pp. 2696-2713. Date of Electronic Publication: 2020 Feb 03 (Print Publication: 2020).

Hypoxia protects against the cell death triggered by oxovanadium-galactomannan complexes in HepG2 cells.

Autor: Meyenberg Cunha-de Padua M; 1Department of Biochemistry and Molecular Biology, Federal University of Parana, Curitiba, Brazil.; Institute for Research on Cancer and Aging of Nice, CNRS-UMR 7284-Inserm U1081, University of Nice Sophia-Antipolis, Centre Antoine Lacassagne, 33 Ave. de Valombrose, 06189 Nice, France.; 3Present Address: INSERM U1065, C3M, 151 Route de St Antoine de Ginestière, BP2 3194, 06204 Nice Cedex 03, France., Noleto GR; 1Department of Biochemistry and Molecular Biology, Federal University of Parana, Curitiba, Brazil., de Oliveira Petkowicz CL; 1Department of Biochemistry and Molecular Biology, Federal University of Parana, Curitiba, Brazil., Cadena SMSC; 1Department of Biochemistry and Molecular Biology, Federal University of Parana, Curitiba, Brazil., Bost F; 3Present Address: INSERM U1065, C3M, 151 Route de St Antoine de Ginestière, BP2 3194, 06204 Nice Cedex 03, France., Pouysségur J; Institute for Research on Cancer and Aging of Nice, CNRS-UMR 7284-Inserm U1081, University of Nice Sophia-Antipolis, Centre Antoine Lacassagne, 33 Ave. de Valombrose, 06189 Nice, France.; 4Medical Biology Department, Centre Scientifique de Monaco (CSM), Monaco, Monaco., Mazure NM; Institute for Research on Cancer and Aging of Nice, CNRS-UMR 7284-Inserm U1081, University of Nice Sophia-Antipolis, Centre Antoine Lacassagne, 33 Ave. de Valombrose, 06189 Nice, France.; 3Present Address: INSERM U1065, C3M, 151 Route de St Antoine de Ginestière, BP2 3194, 06204 Nice Cedex 03, France.

Publikováno v: Cellular & molecular biology letters [Cell Mol Biol Lett] 2019 Mar 22; Vol. 24, pp. 18. Date of Electronic Publication: 2019 Mar 22 (Print Publication: 2019).