Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Meucci W. Ilunga"'
Native proline-rich motifs exploit sequence context to target actin-remodeling Ena/VASP protein ENAH
Autor:
Theresa Hwang, Sara S Parker, Samantha M Hill, Robert A Grant, Meucci W Ilunga, Venkatesh Sivaraman, Ghassan Mouneimne, Amy E Keating
Publikováno v:
eLife, Vol 11 (2022)
The human proteome is replete with short linear motifs (SLiMs) of four to six residues that are critical for protein-protein interactions, yet the importance of the sequence surrounding such motifs is underexplored. We devised a proteomic screen to e
Externí odkaz:
https://doaj.org/article/8d2a3a0e6b2f42ec9501ad4f27397441
Autor:
Theresa Hwang, Sara S Parker, Samantha M Hill, Meucci W Ilunga, Robert A Grant, Ghassan Mouneimne, Amy E Keating
Publikováno v:
eLife, Vol 10 (2021)
Metazoan proteomes contain many paralogous proteins that have evolved distinct functions. The Ena/VASP family of actin regulators consists of three members that share an EVH1 interaction domain with a 100 % conserved binding site. A proteome-wide scr
Externí odkaz:
https://doaj.org/article/85b0b8918f554dc58611c73b71fa31cd
Autor:
Sara S. Parker, Robert A. Grant, Theresa Hwang, Amy E. Keating, Samantha M. Hill, Meucci W. Ilunga, Ghassan Mouneimne
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Metazoan proteomes contain many paralogous proteins that have evolved distinct functions. The Ena/VASP family of actin regulators consists of three members that share an EVH1 interaction domain with a 100% conserved binding site. A proteome-wide scre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c343e0ce5fdc245e3f8e07f0837023
https://doi.org/10.7554/elife.70601
https://doi.org/10.7554/elife.70601
The human proteome is replete with short linear motifs (SLiMs) of 4-6 residues that are critical for protein-protein interactions, yet the importance of the sequence surrounding such motifs is underexplored. We devised a proteomic screen to systemati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d85f06f934d0378d61b5e535ab905eb8
https://doi.org/10.1101/2021.03.22.436451
https://doi.org/10.1101/2021.03.22.436451
