Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mettine H A, Bos"'
Autor:
Daniël Verhoef, Koen M. Visscher, C. Ruben Vosmeer, Ka Lei Cheung, Pieter H. Reitsma, Daan P. Geerke, Mettine H. A. Bos
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
A major drawback in the clinical use of the oral anticoagulants that directly inhibit factor Xa in order to prevent blood clot formation is the potential for life threatening bleeding events. Here the authors describe factor Xa variants that are refr
Externí odkaz:
https://doaj.org/article/b141be2853c5434db46bb976a6a0ac12
Autor:
Carolina E. Touw, Banne Nemeth, Araci M. R. Rondon, Raymond A. van Adrichem, Ton Lisman, Henri H. Versteeg, Inger B. Schipper, Rob G. H. H. Nelissen, Mettine H. A. Bos, Suzanne C. Cannegieter
Publikováno v:
Blood Advances, 6(17), 5232-5243. AMER SOC HEMATOLOGY
Blood Advances, 6(17), 5232-5243. ELSEVIER
Blood Advances, 6(17), 5232-5243. ELSEVIER
It is unknown how lower-leg injury and knee arthroscopy, both associated with venous thromboembolism (VTE), affect coagulation. To study the effect of (1) lower-leg trauma and (2) knee arthroscopy on coagulation, plasma samples of the Prevention of T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ded337765563d1d91dc39c6bdf9ec0c
https://research.rug.nl/en/publications/ab0c21fc-dff3-4e81-a06a-4ed3fd038d71
https://research.rug.nl/en/publications/ab0c21fc-dff3-4e81-a06a-4ed3fd038d71
Autor:
Jafar, Vatandoost, Mettine H A, Bos
Publikováno v:
Biotechnology letters. 44(8)
Based on observations indicating that the γ-carboxylase enzyme has a lower affinity for the protein C (PC) propeptide and that the γ-carboxylase region in the PC propeptide has a higher net charge, expression of recombinant chimeric factor IX (FIX)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f2c4dfadacedae51e1a23c9a23ebc524
https://pubmed.ncbi.nlm.nih.gov/35731352
https://pubmed.ncbi.nlm.nih.gov/35731352
Autor:
Nienke van Rein, Willem M Lijfering, Mettine H A Bos, Martien H Herruer, Helga W Vermaas, Felix J M van der Meer, Pieter H Reitsma
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0164485 (2016)
Risk scores for patients who are at high risk for major bleeding complications during treatment with vitamin K antagonists (VKAs) do not perform that well. BLEEDS was initiated to search for new biomarkers that predict bleeding in these patients.To d
Externí odkaz:
https://doaj.org/article/8e4556d104514dd691ba79eb7bb4ff79
Autor:
Bianca, Op den Brouw, Parviz, Ghezellou, Nicholas R, Casewell, Syed Abid, Ali, Behzad, Fathinia, Bryan G, Fry, Mettine H A, Bos, Maria P, Ikonomopoulou
Publikováno v:
International Journal of Molecular Sciences
Venoms are a rich source of potential lead compounds for drug discovery, and descriptive studies of venom form the first phase of the biodiscovery process. In this study, we investigated the pharmacological potential of crude Pseudocerastes and Erist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::598515338f939bfe45b2c4a2d35ff120
https://pubmed.ncbi.nlm.nih.gov/34199017
https://pubmed.ncbi.nlm.nih.gov/34199017
Autor:
Shohreh Khorshidi, Alireza Zomorodipour, Mehrdad Behmanesh, Jafar Vatandoost, Mettine H. A. Bos
Publikováno v:
Biotechnology Letters, 37(9), 1773-1781
To study the functions of pre-pro leader peptides of the human and porcine prothrombins on the human FIX (hFIX) expression.In silico analysis predicted higher secretion efficiencies for the prothrombins-derived signal peptides, in comparison with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5079b1f4d38394e98b96e760af3e0f
http://hdl.handle.net/1887/107503
http://hdl.handle.net/1887/107503