Team-baseret Læring i Anvendt Klinisk Farmakologi

Autor: Mette Marie Hougaard Christensen, Lotte O’Neil

Publikováno v: Dansk Universitetspaedagogisk Tidsskrift, Vol 16, Iss 30 (2021)

I takt med et øget optag af studerende på de danske universiteter er der i stigende grad behov for at udvide paletten af undervisningsmetoder for at sikre, at undervisningen er studenter-aktiverende og med relevant feedback. For at imødegå udford

Externí odkaz: https://doaj.org/article/4a3da16b59fd4b21a29012c74c56175e

Oral and intravenous pharmacokinetics of metformin with and without oral codeine intake in healthy subjects - a cross-over study

Autor: Amanda Nøddebo Nyrup, Ida Kuhlmann, Kim Brøsen, Flemming Nielsen, Kurt Højlund, Per Damkier, Troels K Bergmann, Tore Bjerregaard Stage, Mette Marie Hougaard Christensen

Publikováno v: Kuhlmann, I, Nyrup, A N, Stage, T B, Christensen, M M H, Bergmann, T K, Damkier, P, Nielsen, F, Højlund, K & Brøsen, K 2021, ' Oral and intravenous pharmacokinetics of metformin with and without oral codeine intake in healthy subjects-a cross-over study ', Clinical and Translational Science, vol. 14, no. 6, pp. 2408-2419 . https://doi.org/10.1111/cts.13107
Clinical and Translational Science
Clinical and Translational Science, Vol 14, Iss 6, Pp 2408-2419 (2021)

The aim of the study was to investigate if there is a clinically relevant drug interaction between metformin and codeine. Volunteers were randomized to receive on four separate occasions: (A) orally administered metformin (1 g), (B) intravenously adm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ca4ea7b909cf012496eb8843f0b927b
https://findresearcher.sdu.dk:8443/ws/files/194645421/cts.13107.pdf

Drug-induced Sialorrhoea

Autor: Maija Bruun Haastrup, Daniel Pilsgaard Henriksen, Mette Marie Hougaard Christensen

Publikováno v: Haastrup, M B, Henriksen, D P & Christensen, M M 2018, ' Drug-induced Sialorrhoea ', Adverse Drug Reaction Bulletin, vol. 313, no. 1, pp. 1211–1214 . https://doi.org/10.1097/FAD.0000000000000037

Sialorrhoea is a common adverse effect of a range of medicines, primarily clozapine. At least a third of patients treated with clozapine suffer from sialorrhoea, and the consequences of this can be socially stigmatising and lead to non-adherence. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ff0cc2cb926423e94c6b7b4b48af68
https://doi.org/10.1097/fad.0000000000000037

Using a limited sampling strategy to investigate the interindividual pharmacokinetic variability in metformin:A large prospective trial

Autor: Kim Brøsen, Tore Bjerregaard Stage, Mette Marie Hougaard Christensen, Sidsel Arnspang Pedersen, Peter Skov Esbech, Ida Kuhlmann

Publikováno v: Kuhlmann, I, Arnspang Pedersen, S, Skov Esbech, P, Bjerregaard Stage, T, Hougaard Christensen, M M & Brøsen, K 2021, ' Using a limited sampling strategy to investigate the interindividual pharmacokinetic variability in metformin : A large prospective trial ', British Journal of Clinical Pharmacology, vol. 87, no. 4, pp. 1963-1969 . https://doi.org/10.1111/bcp.14591

Aims: Recently a limited sampling strategy (LSS) for determination of metformin' pharmacokinetics was developed. The LSS utilizes the plasma concentration of metformin 3 and 10 hours after oral intake of a single dose to estimate the area under the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::646972af0eb41422f766cef9a159e6a0
https://findresearcher.sdu.dk:8443/ws/files/174894174/bcp.14591.pdf

The Danish model for the quick and safe implementation of infliximab and etanercept biosimilars

Autor: Stig Andersen, Thomas Bo Jensen, Hanne Rolighed Christensen, Dorthe Bartels, Mette Marie Hougaard Christensen, Eva Aggerholm Sædder, Lars Peter Nielsen, Birgitte Klindt Poulsen

Publikováno v: Jensen, T B, Bartels, D, Sædder, E A, Poulsen, B K, Andersen, S E, Christensen, M M H, Nielsen, L & Christensen, H R 2020, ' The Danish model for the quick and safe implementation of infliximab and etanercept biosimilars ', European Journal of Clinical Pharmacology, vol. 76, no. 1, pp. 35–40 . https://doi.org/10.1007/s00228-019-02765-3
Jensen, T B, Bartels, D, Sædder, E A, Poulsen, B K, Andersen, S E, Christensen, M M H, Nielsen, L & Christensen, H R 2020, ' The Danish model for the quick and safe implementation of infliximab and etanercept biosimilars ', European Journal of Clinical Pharmacology, vol. 76, no. 1, pp. 35-40 . https://doi.org/10.1007/s00228-019-02765-3

Purpose A rapidly increasing use of biological drugs has led to substantial costs. Shift to biosimilars enables considerable reduction of these costs without jeopardizing the treatment of patients, but most countries have extensive possibilities of u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cafd9a0788c1ad2f93650d75928bf814
https://vbn.aau.dk/da/publications/253195a6-4e8a-4934-ad4f-d6895a914a7b