Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Mette Praetorius-Ibba"'
Autor:
Ryan Cottrell, Mette Prætorius-Ibba, Muthusamy Thangavel, Timothy Chen, Joy Maria Mitchell, Lenguyen Huynh
Publikováno v:
Cell Cycle. 9:3184-3190
Cells respond to nutrient deprivation a variety of ways. In addition to global downregulation of cap-dependent protein synthesis mediated by the GCN2 and mTORC1 signaling pathways, a catabolic process autophagy is upregulated to provide internal buil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bfc6d60c6a16b31fb2a23bd3c3beff2
https://doi.org/10.4161/cc.9.15.12525
https://doi.org/10.4161/cc.9.15.12525
Autor:
Altaf A. Wani, Mette Prætorius-Ibba, Qun Zhao, Qianzheng Zhu, Gulzar Wani, Qi-En Wang, Song Qin, Mohamed A. El-Mahdy, Srinivas Patnaik
Publikováno v:
Nucleic Acids Research
The Xeroderma Pigmentosum group C (XPC) protein is indispensable to global genomic repair (GGR), a subpathway of nucleotide excision repair (NER), and plays an important role in the initial damage recognition. XPC can be modified by both ubiquitin an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc79d34345231ae820ce9c8f477478f
https://doi.org/10.1093/nar/gkm550
https://doi.org/10.1093/nar/gkm550
Autor:
Mette Prætorius-Ibba, Song Qin, Qi-En Wang, Qianzheng Zhu, Mohamed A. El-Mahdy, Altaf A. Wani, Gulzar Wani
Publikováno v:
DNA Repair. 6:578-587
The replication checkpoint protein Claspin is important for maintenance of genomic stability and is required for cells to overcome genotoxic stress. Upon UV-induced DNA damage, Claspin is required for activation of the ATR-mediated DNA damage checkpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c5339e4239a4e2eb9003d835803c560
https://doi.org/10.1016/j.dnarep.2006.11.009
https://doi.org/10.1016/j.dnarep.2006.11.009
Publikováno v:
Biochemistry. 45:3646-3652
The aminoacyl-tRNA synthetases are divided into two unrelated structural classes, with lysyl-tRNA synthetase (LysRS) being the only enzyme represented in both classes. On the basis of the structure of l-lysine complexed with Pyrococcus horikoshii cla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26b5773d9e47b3bc1bf1b41c0a6c0932
https://doi.org/10.1021/bi0523005
https://doi.org/10.1021/bi0523005
Autor:
Birgit Christine Bønsager, Peter Kresten Nielsen, Birte Svensson, Mette Prætorius-Ibba, Maher Abou Hachem, Kenji Fukuda
Publikováno v:
Journal of Biological Chemistry. 280:14855-14864
The barley alpha-amylase/subtilisin inhibitor (BASI) inhibits alpha-amylase 2 (AMY2) with subnanomolar affinity. The contribution of selected side chains of BASI to this high affinity is discerned in this study, and binding to other targets is invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e515080842d85d41971d942077edc39
https://doi.org/10.1074/jbc.m412222200
https://doi.org/10.1074/jbc.m412222200
Autor:
Mette Prætorius-Ibba, Michael Ibba
Publikováno v:
Molecular Microbiology. 48:631-637
Summary Accurate aminoacyl-tRNA synthesis is essential for correct translation of the genetic code in all organisms. Whereas many aspects of this process are conserved, others display a surprisingly high level of divergence from the canonical Escheri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ca01bc4e408b224637f9086bfb63fd9
https://doi.org/10.1046/j.1365-2958.2003.03330.x
https://doi.org/10.1046/j.1365-2958.2003.03330.x
Autor:
Peter E. Nielsen, Carsten Behrens, Ki-Hyun Kim, Xue-Jun Fan, Jens N. Nielsen, Mette Praetorius-Ibba, Michael Ibba, Xavier Doisy
Publikováno v:
Tetrahedron. 56:9443-9449
A major limitation of conventional site-directed mutagenesis is that substitutions are restricted to the 20 naturally occurring amino acids. While this problem can be circumvented in vitro to allow the site-specific incorporation of non-canonical ami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b643eda709f36315adf1768717740b0
https://doi.org/10.1016/s0040-4020(00)00828-0
https://doi.org/10.1016/s0040-4020(00)00828-0
Publikováno v:
Nucleic Acids Research. 27:3631-3637
Sequence-specific interactions between aminoacyl-tRNA synthetases and their cognate tRNAs ensure both accurate RNA recognition and the efficient catalysis of aminoacylation. The effects of tRNA(Trp)variants on the aminoacylation reaction catalyzed by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b0e3d0795243bd5014d5fc08bdc5066
https://doi.org/10.1093/nar/27.18.3631
https://doi.org/10.1093/nar/27.18.3631
Autor:
Gilles Monnet, Torsten Nilsson-Tillgren, Morten C. Kielland-Brandt, Bernd Meyhack, Albert Hinnen, Mette Prætorius-Ibba
Publikováno v:
Current Genetics. 32:190-196
The majority of secreted acid phosphatase in Saccharomyces cerevisiae is encoded by the PH05 gene. The secretion level of this acid phosphatase is directly determined by its level of glycosylation. Consequently, PHO5-11-encoded acid phosphatase which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef092a95733ee07910ef0875496b194d
https://doi.org/10.1007/s002940050265
https://doi.org/10.1007/s002940050265
Inhibition of the autophagic pathway has recently revealed promising results in increasing pro-death activity of multiple cancer therapeutics. Here, we discuss our findings regarding the autophagy-blocking and anti-neoplastic effects of a synthetic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6319e62263db39e1e95516b19357b9e4
https://europepmc.org/articles/PMC3337842/
https://europepmc.org/articles/PMC3337842/
