The prevalence and risk factors for cognitive impairment in obesity and NAFLD

Autor: Charlotte W. Wernberg, Lea L. Grønkjær, Birgitte Gade Jacobsen, Vineesh Indira Chandran, Aleksander Krag, Jonas H. Graversen, Karin Weissenborn, Hendrik Vilstrup, Mette M. Lauridsen

Publikováno v: Hepatology Communications, Vol 7, Iss 7 (2023)

Background:. Severe obesity may be accompanied by cognitive dysfunction and NAFLD, but the associations remain unclear. We describe the prevalence and features of cognitive dysfunction and examine the associations between cognitive dysfunction and th

Externí odkaz: https://doaj.org/article/e7c0b8f5f24541e4848912a555dc33fc

Prediction of overt hepatic encephalopathy by the continuous reaction time method and the portosystemic encephalopathy syndrome test in clinically mentally unimpaired patients with cirrhosis.

Autor: Charlotte W Wernberg, Ove B Schaffalitzky de Muckadell, Hendrik Vilstrup, Mette M Lauridsen

Publikováno v: PLoS ONE, Vol 14, Iss 12, p e0226283 (2019)

BACKGROUND AND AIM:Predicting overt hepatic encephalopathy (OHE) is important because the condition is frequent, often requires hospitalization and is potentially preventable. The risk of OHE is related to pre-existing discrete cognitive defects, and

Externí odkaz: https://doaj.org/article/20edde70260947e09c79b6c8f314b7bf

settingsOpen AccessReviewThe Role of Diagnostic Biomarkers, Omics Strategies, and Single-Cell Sequencing for Nonalcoholic Fatty Liver Disease in Severely Obese Patients

Autor: Charlotte W. Wernberg, Kim Ravnskjaer, Mette M. Lauridsen and Maja Thiele

Publikováno v: Journal of Clinical Medicine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::0878a1eb1d0f04c7c93ac7269a62cc41

A pilot study of golexanolone, a new GABA-A receptor-modulating steroid antagonist, in patients with covert hepatic encephalopathy.

Autor: Montagnese S; University of Padova, Padova, Italy., Lauridsen M; Hospital of South West Jutland, Esbjerg, Denmark., Vilstrup H; Aarhus University, Aarhus, Denmark., Zarantonello L; University of Padova, Padova, Italy., Lakner G; CRU Hungary Kft., Miskolc, Hungary., Fitilev S; State Budgetary Healthcare Institution 'City Polyclinic №2', Moscow, Russia., Zupanets I; Clinical and Diagnostics Center, National University of Pharmacy, Kharkiv, Ukraine., Kozlova I; State Healthcare Institution 'Saratov Clinical Hospital #5', Saratov, Russia., Bunkova E; Medical University 'Reaviz', Samara, Russia., Tomasiewicz K; Department of Infectious Diseases and Hepatology, Medical University of Lublin, Poland., Berglund JE; CTC Clinical Trial Consultants AB, Uppsala, Sweden., Rorsman F; Dept of Gastroenterology and Hepatology, University Hospital Uppsala, Sweden., Hagström H; Unit of Hepatology, Department of Upper GI Diseases, Karolinska University Hospital, Stockholm, Sweden., Kechagias S; Department of Health, Medicine, and Caring Sciences, Linköping University, Linköping, Sweden., Ocklind CE; Dept of Gastroenterology, Västerås Hospital, Sweden., Mauney J; Array Biostatistics, Wilmington, NC, USA., Thunarf F; LINK Medical Research AB, Uppsala, Sweden., Mokhatarani M; Umecrine Cognition AB, Stockholm, Sweden., Bäckström T; Umecrine Cognition AB, Stockholm, Sweden; Department of Clinical Sciences, Obstetrics and Gynecology, Umeå University, SE-901 87 Umeå, Sweden., Doverskog M; Umecrine Cognition AB, Stockholm, Sweden., Lins LE; Umecrine Cognition AB, Stockholm, Sweden., Månsson M; Umecrine Cognition AB, Stockholm, Sweden., Samuelson P; Umecrine Cognition AB, Stockholm, Sweden., Nilsson D; Umecrine Cognition AB, Stockholm, Sweden., Schalling M; Umecrine Cognition AB, Stockholm, Sweden; Department of Molecular Medicine and Surgery and the Center for Molecular Medicine at Karolinska Institutet., Sweden., Johansson M; Umecrine Cognition AB, Stockholm, Sweden; Department of Clinical Sciences, Obstetrics and Gynecology, Umeå University, SE-901 87 Umeå, Sweden., Arlander E; Umecrine Cognition AB, Stockholm, Sweden., Scharschmidt BF; Umecrine Cognition AB, Stockholm, Sweden. Electronic address: bruce.scharschmidt@gmail.com.

Publikováno v: Journal of hepatology [J Hepatol] 2021 Jul; Vol. 75 (1), pp. 98-107. Date of Electronic Publication: 2021 Apr 21.