Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mette Kirkegaard"'
Publikováno v:
Image Analysis and Stereology, Vol 24, Iss 2, Pp 69-76 (2011)
The aim of the present study is to estimate the total number of the sensory hair cells (chalice innervated and bouton innervated) and supporting cells in the mouse utricular sensory epithelium at two different time points after systemic kanamycin tre
Externí odkaz:
https://doaj.org/article/d84a13fd7c50447eb8a205fa3d0a42de
Autor:
Hans Ehrsson, Elias S.J. Arnér, Maria Shoshan, Inger Wallin, Mette Kirkegaard, Pascal Dammeyer, Victoria Hellberg, Göran Laurell
Publikováno v:
Acta Oto-Laryngologica
Conclusion Inhibition of thioredoxin reductase (TrxR) may be a contributing factor in cisplatin-induced ototoxicity. Direct exposure of organ of Corti to cisplatin and oxaliplatin gives equal loss of hair cells. Objectives Platinum-containing drugs a
Dietary restriction reduces age-related degeneration of stria vascularis in the inner ear of the rat
Publikováno v:
Experimental Gerontology; Vol 48
We report here beneficial effects of life-long dietary restriction on the progression of age-associated cochlear degeneration in female Sprague-Dawley rats. Thirty-month old rats on a 70% dietary restriction were compared to ad libitum fed age-matche
Autor:
Mats Ulfendahl, Futoshi Watanabe, Cecilia Gont, Suguru Matsumoto, Paula Mannström, Anders Fridberger, Mette Kirkegaard
Publikováno v:
European Journal of Neuroscience. 32:717-724
Noise, ototoxic substances and various genetic factors are common causes of profound hearing loss. Cochlear implants can often restore hearing in these cases, but only if a sufficient number of responsive auditory nerve fibers remain. Over time, thes
Publikováno v:
Severinsen, S A, Sørensen, M S, Kirkegaard, M & Nyengaard, J R 2010, ' Stereological estimation of total cell numbers in the young human utricular macula ', Acta Oto-Laryngologica, vol. 130, no. 7, pp. 773-779 . https://doi.org/10.3109/00016480903397694
Conclusion: There is no change in the total cell population and hair cell:supporting cell ratio in the human utricular macula from gestational week 16 and onwards, whereas the lower hair cell:supporting cell ratio and lower total number of cells in t
Autor:
Stig Å. Severinsen, Jens R. Nyengaard, Merete K. Raarup, Mats Ulfendahl, Mette Kirkegaard, Lise Wogensen
Publikováno v:
Severinsen, S A, Raarup, M K, Ulfendahl, M, Wogensen, L, Nyengaard, J R & Kirkegaard, M 2008, ' Type I hair cell degeneration in the utricular macula of the waltzing guinea pig. ', Hearing Research, vol. 236, pp. 33-41 . https://doi.org/10.1016/j.heares.2007.11.009
Waltzing guinea pigs are an inbred guinea pig strain with a congenital and progressive balance and hearing disorder. A unique rod-shaped structure is found in the type I vestibular hair cells, that traverses the cell in an axial direction, extending
Publikováno v:
JARO - Journal of the Association for Research in Otolaryngology. 4:422-443
In humans, hair cell loss often leads to hearing and balance impairments. Hair cell replacement is vigorous and spontaneous in avians and nonmammalian vertebrates. In mammals, in contrast, it occurs at a very low rate, or not at all, presumably becau
Publikováno v:
Journal of Comparative Neurology. 438:433-444
The inner ear macular sensory epithelia of the Daubenton’s bat were examined quantitatively to estimate the area and total number of hair cells. Ultrastructural examination of the sensory epithelium reveals two main types of hair cells: the chalice
Publikováno v:
Naturwissenschaften. 87:83-86
In both humans and mice the number of hair cells in the inner ear sensory epithelia declines with age, indicating cell death (Park et al. 1987; Rosenhall 1973). However, recent reports demonstrate the ability of the vestibular sensory epithelia to re
Autor:
Futoshi, Watanabe, Mette, Kirkegaard, Suguru, Matsumoto, Cecilia, Gont, Paula, Mannström, Mats, Ulfendahl, Anders, Fridberger
Publikováno v:
The European journal of neuroscience. 32(5)
Noise, ototoxic substances and various genetic factors are common causes of profound hearing loss. Cochlear implants can often restore hearing in these cases, but only if a sufficient number of responsive auditory nerve fibers remain. Over time, thes