The clinical importance of BRCAness in a population-based cohort of Danish epithelial ovarian cancer

Autor: Anders Jakobsen, Dorthe Ørnskov, Mads Malik Aagaard Jørgensen, Marianne Waldstrøm, Karina Dahl-Steffensen, Mette Hjortkjær, Erik Søgaard-Andersen

Publikováno v: Hjortkjær, M, Malik Aagaard Jørgensen, M, Waldstrøm, M, Ørnskov, D, Søgaard-Andersen, E, Jakobsen, A & Dahl-Steffensen, K 2019, ' The clinical importance of BRCAness in a population-based cohort of Danish epithelial ovarian cancer ', International Journal of Gynecological Cancer, vol. 29, no. 1, pp. 166-173 . https://doi.org/10.1136/ijgc-2018-000017

ObjectiveGermline mutations inBRCA1/2genes predict improved survival and sensitivity to treatment with poly(adenosine-diphosphate-ribose) polymerase inhibitors in epithelial ovarian carcinoma. The prognostic importance of other genetic alterations le

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0525ae738ef45e5c20ca83f7de303827
https://doi.org/10.1136/ijgc-2018-000017

Tissue immune response in epithelial ovarian carcinoma

Autor: Anders Jakobsen, Jon Røikjær Henriksen, Mette Hjortkjær, Karina Dahl Steffensen, Marianne Waldstrøm, Caroline Brenner Thomsen, Frede Donskov, Christina Braad Petersen

Publikováno v: Henriksen, J, Donskov, F, Waldstrom, M, Hjortkjaer, M, Petersen, C B, Thomsen, C B, Jakobsen, A K M & Steffensen, K D 2019, ' Tissue immune response in epithelial ovarian carcinoma ', Journal of Clinical Oncology, vol. 37, no. 15 Supplement, 2625, pp. 2625-2625 . https://doi.org/10.1200/JCO.2019.37.15suppl.2625

2625 Background: Epithelial ovarian cancer (EOC) is a highly malignant disease with a fatal outcome for most patients. During recent years immunological mechanisms have proven important in relation to the treatment and prognosis of cancer, but within

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https://portal.findresearcher.sdu.dk/da/publications/055988ce-656d-4c20-aa07-01c4a77e9ca2

Veliparib and topotecan for patients with platinum-resistant or partially platinum-sensitive relapse of epithelial ovarian cancer with BRCA negative or unknown BRCA status

Autor: Hanne Kanstrup, Karina Dahl Steffensen, Mette Hjortkjær, Anders Jakobsen

Publikováno v: Hjortkjær, M, Kanstrup, H, Jakobsen, A & Steffensen, K D 2018, ' Veliparib and topotecan for patients with platinum-resistant or partially platinum-sensitive relapse of epithelial ovarian cancer with BRCA negative or unknown BRCA status ', Cancer Treatment and Research Communications, vol. 14, pp. 7-12 . https://doi.org/10.1016/j.ctarc.2017.09.001
University of Southern Denmark
Hjortkjær, M, Kanstrup, H, Jakobsen, A & Dahl Steffensen, K 2018, ' Veliparib and topotecan for patients with platinum-resistant or partially platinum-sensitive relapse of epithelial ovarian cancer with BRCA negative or unknown BRCA status ', Cancer Treatment and Research Communications, vol. 14, pp. 7-12 . https://doi.org/10.1016/j.ctarc.2017.09.001
Hjortkjær, M, Kanstrup, H, Jakobsen, A & Dahl Steffensen, K 2018, ' Veliparib and topotecan for patients with platinum-resistant or partially platinum-sensitive relapse of epithelial ovarian cancer with BRCA negative or unknown BRCA status ', Dansk Gynækologisk Cancer Gruppe, Årsmøde 2018, København, Denmark, 05/04/2018-05/04/2018 .

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c90bc5bd7c36c123b7bd40954863c326
https://vbn.aau.dk/da/publications/88b3f2e8-acf5-483b-8b6d-b2c0b3e164e2

The prognostic value of BRCA1 and PARP expression in epithelial ovarian carcinoma – immunohistochemical detection

Autor: Karina Dahl Steffensen, Mette Hjortkjær, Marianne Waldstrøm, Erik Søgaard-Andersen, Anders Jakobsen, Hanne Kanstrup

Publikováno v: University of Southern Denmark
Hjortkjær, M, Waldstrøm, M, Kanstrup, H, Søgaard-Andersen, E, Jakobsen, A & Dahl Steffensen, K 2015, ' The prognostic value of BRCA1 and PARP expression in epithelial ovarian carcinoma – immunohistochemical detection ', Årsmøde, Dansk Gynækologisk Cancer Gruppe, 2015, Vejle, Denmark, 19/03/2015-19/03/2015 .
Hjortkjær, M, Waldstrøm, M, Jakobsen, A, Kanstrup, H, Søgaard-Andersen, E & Dahl Steffensen, K 2016, ' The prognostic value of BRCA1 and PARP expression in epithelial ovarian carcinoma – immunohistochemical detection ', Annual Meeting of the Danish Pathology Society (DPAS) 2016, København, Denmark, 10/03/2016-12/03/2016 .
Hjortkjær, M, Waldstrøm, M, Jakobsen, A, Kanstrup, H, Søgaard-Andersen, E & Dahl Steffensen, K 2017, ' The Prognostic Value of BRCA1 and PARP Expression in Epithelial Ovarian Carcinoma : Immunohistochemical Detection ', International Journal of Gynecological Pathology, vol. 36, no. 2, pp. 180-189 . https://doi.org/10.1097/PGP.0000000000000310
Hjortkjær, M, Waldstrøm, M, Kanstrup, H, Søgaard-Andersen, E, Jakobsen, A & Dahl Steffensen, K 2014, ' The prognostic value of BRCA1 and PARP expression in epithelial ovarian carcinoma – immunohistochemical detection ', 15th biennial meeting of the International Gynecologic Cancer Society., Melbourne, Australia, 08/11/2014-11/12/2014 .

BRCA1/2 mutation status in epithelial ovarian cancer (EOC) presently relies on genetic testing which is resource consuming. Immunohistochemistry is cheap, fairly reproducible, and may identify gene product alterations due to both germline and somatic

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http://findresearcher.sdu.dk/portal/en/publications/the-prognostic-value-of-brca1-and-parp-expression-in-epithelial-ovarian-carcinoma--immunohistochemical-detection(8e981c2b-1851-4a26-9555-fdfa3b1e4340).html