Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Mette H. Poulsen"'
Autor:
Lara Magni, Haoran Yu, Nynne M. Christensen, Mette H. Poulsen, Alexander Frueh, Ganga Deshar, Astrid Z. Johansen, Julia S. Johansen, Stephan A. Pless, Niklas R. Jørgensen, Ivana Novak
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Background The purinergic P2X7 receptor (P2X7R) plays an important role in the crosstalk between pancreatic stellate cells (PSCs) and cancer cells, thus promoting progression of pancreatic ductal adenocarcinoma (PDAC). Single nucleotide poly
Externí odkaz:
https://doaj.org/article/fe7eeb715b5d4909a0fb35c22c90c785
Autor:
Mette H. Poulsen, Feng Xue, Svetlana R. Maurya, Stefanie Kickinger, Samuel Usher, Petrine Wellendorph, Alicia Lundby, Stephan A. Pless
Publikováno v:
Biophysical Journal. 122:249a
Autor:
Andrew J R, Plested, Mette H, Poulsen
Publikováno v:
Methods in enzymology. 652
Combining crosslinking strategies with electrophysiology, biochemistry, and structural in silico analysis is a powerful tool to study transient movements of ion channels during gating. This chapter describes crosslinking in living cells using cystein
Autor:
Mette H. Poulsen, Andrew J.R. Plested, Valentina Ghisi, Anahita Poshtiban, Viktoria Klippenstein
Publikováno v:
Proceedings of the National Academy of Sciences. 116:13358-13367
Ionotropic glutamate receptors (iGluRs) are responsible for fast synaptic transmission throughout the vertebrate nervous system. Conformational changes of the transmembrane domain (TMD) underlying ion channel activation and desensitization remain poo
Autor:
Stephan A. Pless, Sarune Bielickaite, Debayan Sarkar, Mette H. Poulsen, Alexander S. Hauser, Federica Gasparri
Publikováno v:
Gasparri, F, Sarkar, D, Bielickaite, S, Poulsen, M H, Hauser, A S & Pless, S A 2022, ' P2X2 receptor subunit interfaces are missense variant hotspots, where mutations tend to increase apparent ATP affinity ', British Journal of Pharmacology, vol. 179, no. 14, pp. 3859-3874 . https://doi.org/10.1111/bph.15830
Background and PurposeP2X receptors (P2XRs) are trimeric ligand-gated ion channels (LGICs) that open a cation-selective pore in response to ATP binding to their large extracellular domain (ECD). The seven known P2XR subtypes can assemble as homo- or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90fa4d1e153b4f2c344dd4b9e86e9605
https://doi.org/10.1101/2021.03.26.436616
https://doi.org/10.1101/2021.03.26.436616
Autor:
Andrew J.R. Plested, Mette H. Poulsen
Publikováno v:
Methods in Enzymology ISBN: 9780323853743
Combining crosslinking strategies with electrophysiology, biochemistry, and structural in silico analysis is a powerful tool to study transient movements of ion channels during gating. This chapter describes crosslinking in living cells using cystein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b018fe61051ab213cbaad26895c8a754
https://doi.org/10.1016/bs.mie.2021.03.005
https://doi.org/10.1016/bs.mie.2021.03.005
Autor:
Keith K. Khoo, Stephan A. Pless, Robert Tampé, Federica Gasparri, Han Chow Chua, Matthias Wulf, Iacopo Galleano, Hendrik Harms, Ralph Wieneke, Mette H. Poulsen
Publikováno v:
Khoo, K K, Galleano, I, Gasparri, F, Wieneke, R, Harms, H, Poulsen, M H, Chua, H C, Wulf, M, Tampé, R & Pless, S A 2020, ' Chemical modification of proteins by insertion of synthetic peptides using tandem protein trans-splicing ', Nature Communications, vol. 11, no. 1, 2284 . https://doi.org/10.1038/s41467-020-16208-6
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications
Nature Communications, 11(1). NATURE PUBLISHING GROUP
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications
Nature Communications, 11(1). NATURE PUBLISHING GROUP
Manipulation of proteins by chemical modification is a powerful way to decipher their function. However, most ribosome-dependent and semi-synthetic methods have limitations in the number and type of modifications that can be introduced, especially in
Publikováno v:
Journal of Medicinal Chemistry. 61:8048-8053
Ionotropic glutamate receptors (iGluRs) play a critical role in normal brain function and neurodegenerative diseases. Development of light-dependent compounds would enable studies of iGluRs within intact mammalian neural tissue, as light is noninvasi
Publikováno v:
Poulsen, M H, Fang, J & Pless, S A 2019, ' Elucidating the Function and Cell-Specific Interactions of P2X7 Receptor Variants Linked to Mental Disorders ', pp. 109A-110A . https://doi.org/10.1016/j.bpj.2018.11.624
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dda90d6b27f21355eca174d6a1dc25e8
https://curis.ku.dk/portal/da/publications/elucidating-the-function-and-cellspecific-interactions-of-p2x7-receptor-variants-linked-to-mental-disorders(89d1920e-181d-49ff-9a8e-aed094db43e4).html
https://curis.ku.dk/portal/da/publications/elucidating-the-function-and-cellspecific-interactions-of-p2x7-receptor-variants-linked-to-mental-disorders(89d1920e-181d-49ff-9a8e-aed094db43e4).html
Autor:
Svetlana Rajkumar Maurya, Johann Sigurdsson, Mette H. Poulsen, Alicia Lundby, Stephan A. Pless
Publikováno v:
Biophysical Journal. 118:584a