Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mette H. Jensen"'
Autor:
Mette H. Jensen, Samra J. Sanni, Ditte Riber, Jens J. Holst, Mette M. Rosenkilde, Alexander H. Sparre-Ulrich
Publikováno v:
Molecular Metabolism, Vol 88, Iss , Pp 102006- (2024)
Objectives: Obesity represents a global health crisis with significant patient burdens and healthcare costs. Despite the advances with glucagon-like peptide-1 (GLP-1) receptor agonists in treating obesity, unmet needs remain. This study characterizes
Externí odkaz:
https://doaj.org/article/25f7b2dd9c3443ce984912d0de8ad0d3
Autor:
Bolette Hartmann, Liva S.L. Krogh, Filip K. Knop, Mette M. Rosenkilde, Alexander Hovard Sparre-Ulrich, Tina Vilsbøll, Kirsa Skov-Jeppesen, Jens J. Holst, Mette H. Jensen, Mikkel B. Christensen, Flemming Dela, Lærke S. Gasbjerg, Signe Stensen
Publikováno v:
Stensen, S, Gasbjerg, L S, Krogh, L L, Skov-Jeppesen, K, Sparre-Ulrich, A H, Jensen, M H, Dela, F, Hartmann, B, Vilsbøll, T, Holst, J J, Rosenkilde, M M, Christensen, M B & Knop, F K 2021, ' Effects of endogenous GIP in patients with type 2 diabetes ', European Journal of Endocrinology, vol. 185, no. 1, pp. 33-45 . https://doi.org/10.1530/EJE-21-0135
Objective The insulinotropic effect of exogenous, intravenously infused glucose-dependent insulinotropic polypeptide (GIP) is impaired in patients with type 2 diabetes. We evaluated the effects of endogenous GIP in relation to glucose and bone metabo
Autor:
Lærke S. Gasbjerg, Mette M. Rosenkilde, Amalie R. Lanng, Natasha C. Bergmann, Mikkel B. Christensen, Mads M. Helsted, Jens J. Holst, Maria Buur Nordskov Gabe, Tina Vilsbøll, Simon Veedfald, Bolette Hartmann, Alexander Hovard Sparre-Ulrich, Mette H. Jensen, Filip K. Knop, Signe Stensen
Publikováno v:
Diabetes. 68:906-917
The incretin hormones glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) are secreted postprandially and contribute importantly to postprandial glucose tolerance. In this study, we assessed the individual and combi
Autor:
Max Soegaard, Annette Knoblich, Willem A. de Jongh, Peter G. Kremsner, Nicaise Tuikue Ndam, Steven G. Reed, Lars Poulsen, Mihály Sulyok, Morten Nielsen, Odile Leroy, Mafalda Resende, Carlos Lamsfus Calle, Javier Ibáñez, Meral Esen, Ali Salanti, Thor G. Theander, Saadou Issifou, Randall F. Howard, Helle Holm Smedegaard, Benjamin Mordmüller, Mette H Jensen, Philippe Deloron, Sophie Houard, Charlotte Dyring, Adrian J. F. Luty, Diane Egger-Adam, Sisse B. Ditlev
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Mordmüller, B, Sulyok, M, Egger-Adam, D, Resende, M, de Jongh, W A, Jensen, M H, Smedegaard, H H, Ditlev, S B, Soegaard, M, Poulsen, L, Dyring, C, Calle, C L, Knoblich, A, Ibáñez, J, Esen, M, Deloron, P, Ndam, N, Issifou, S, Houard, S, Howard, R F, Reed, S G, Leroy, O, Luty, A J F, Theander, T G, Kremsner, P G, Salanti, A & Nielsen, M A 2019, ' First-in-human, randomized, double-blind clinical trial of differentially adjuvanted PAMVAC, a vaccine candidate to prevent pregnancy-associated malaria ', Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, vol. 69, no. 9, pp. 1509-1516 . https://doi.org/10.1093/cid/ciy1140
Mordmüller, B, Sulyok, M, Egger-Adam, D, Resende, M, de Jongh, W A, Jensen, M H, Smedegaard, H H, Ditlev, S B, Soegaard, M, Poulsen, L, Dyring, C, Calle, C L, Knoblich, A, Ibáñez, J, Esen, M, Deloron, P, Ndam, N, Issifou, S, Houard, S, Howard, R F, Reed, S G, Leroy, O, Luty, A J F, Theander, T G, Kremsner, P G, Salanti, A & Nielsen, M A 2019, ' First-in-human, randomized, double-blind clinical trial of differentially adjuvanted PAMVAC, a vaccine candidate to prevent pregnancy-associated malaria ', Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, vol. 69, no. 9, pp. 1509-1516 . https://doi.org/10.1093/cid/ciy1140
Background Malaria in pregnancy has major impacts on mother and child health. To complement existing interventions, such as intermittent preventive treatment and use of impregnated bed nets, we developed a malaria vaccine candidate with the aim of re
Autor:
Maria E. K. Lie, Petrine Wellendorph, Bente Frølund, Maria Damgaard, Stine B. Vogensen, Hans Bräuner-Osborne, Mette H. Jensen, Anas Al-Khawaja, Bolette Kragholm, Rasmus P. Clausen, Jette G. Petersen
Publikováno v:
Neurochemical Research. 39:1988-1996
The γ-aminobutyric acid (GABA) transporters (GATs) are key membrane transporter proteins involved in the termination of GABAergic signaling at synapses in the mammalian brain and proposed drug targets in neurological disorders such as epilepsy. To d
Publikováno v:
Journal of Molecular Biology. 414:96-105
Ionotropic glutamate receptors (iGluRs) mediate excitatory neurotransmission in the central nervous system and play key roles in brain development and disease. iGluRs have two distinct extracellular domains, but the functional role of the distal N-te