Influence of psychopathology and metabolic parameters on quality of life in patients with first-episode psychosis before and after initial antipsychotic treatment

Autor: Anne Sofie A. Dahl, Victor Sørensen, Karen S. Ambrosen, Mikkel E. Sørensen, Grímur H. Mohr, Mette Ø. Nielsen, Kirsten B. Bojesen, Birte Y. Glenthøj, Margaret Hahn, Julie Midtgaard, Bjørn H. Ebdrup

Publikováno v: Schizophrenia, Vol 9, Iss 1, Pp 1-7 (2023)

Abstract The impact of psychological and physical health on quality of life (QoL) in patients with early psychosis remain relatively unexplored. We evaluated the predictive value of psychopathological and metabolic parameters on QoL in antipsychotic-

Externí odkaz: https://doaj.org/article/cba3c37c79124a0f96b61fd2f0dfff77

Negative symptoms and social cognition as mediators of the relationship between neurocognition and functional outcome in schizophrenia

Autor: Giulia M. Giordano, Pasquale Pezzella, Armida Mucci, Stephen F. Austin, Andreas Erfurth, Birte Glenthøj, Alex Hofer, Jan Hubenak, Jan Libiger, Ingrid Melle, Mette Ø. Nielsen, Janusz K. Rybakowski, Pawel Wojciak, Silvana Galderisi, Gabriele Sachs

Publikováno v: Frontiers in Psychiatry, Vol 15 (2024)

IntroductionIn this study we assessed the contribution of psychopathology, including the two domains of negative symptoms (motivational deficit and expressive deficit), processing speed as an index of neurocognition, and emotion recognition, as an in

Externí odkaz: https://doaj.org/article/01a986a641024181a0f3284e763cd995

The impact of schizophrenia and intelligence on the relationship between age and brain volume

Autor: Maria H. Jensen, Nikolaj Bak, Egill Rostrup, Mette Ø. Nielsen, Christos Pantelis, Birte Y. Glenthøj, Bjørn H. Ebdrup, Birgitte Fagerlund

Publikováno v: Schizophrenia Research: Cognition, Vol 15, Iss , Pp 1-6 (2019)

Age has been shown to have an impact on both grey (GM) and white matter (WM) volume, with a steeper slope of age-related decline in schizophrenia compared to healthy controls. In schizophrenia, the relation between age and brain volume is further com

Externí odkaz: https://doaj.org/article/b828c85a271a481ba3a5233210ab38d5

Fibre density and fibre-bundle cross-section of the corticospinal tract are distinctly linked to psychosis-specific symptoms in antipsychotic-naïve patients with first-episode schizophrenia

Autor: Tina D. Kristensen, Jayachandra M. Raghava, Martin W. Skjerbæk, Thijs Dhollander, Warda Syeda, Karen S. Ambrosen, Kirsten B. Bojesen, Mette Ø. Nielsen, Christos Pantelis, Birte Y. Glenthøj, Bjørn H. Ebdrup

Publikováno v: European Archives of Psychiatry and Clinical Neuroscience.

Multiple lines of research support the dysconnectivity hypothesis of schizophrenia. However, findings on white matter (WM) alterations in patients with schizophrenia are widespread and non-specific. Confounding factors from magnetic resonance image (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d566e07b634c433bf601e11e070ef530
https://doi.org/10.1007/s00406-023-01598-7

Scalability of the Positive and Negative Syndrome Scale in first-episode schizophrenia assessed by Rasch models

Autor: Lone Baandrup, Peter Allerup, Mette Ø. Nielsen, Signe W. Düring, Kirsten B. Bojesen, Stefan Leucht, Silvana Galderisi, Armida Mucci, Paola Bucci, Celso Arango, Covadonga M. Díaz‐Caneja, Paola Dazzan, Philip McGuire, Arsime Demjaha, Bjørn H. Ebdrup, Wolfgang W. Fleischhacker, René S. Kahn, Birte Y. Glenthøj

Publikováno v: Baandrup, L, Allerup, P, Nielsen, M Ø, Düring, S W, Bojesen, K B, Leucht, S, Galderisi, S, Mucci, A, Bucci, P, Arango, C, Díaz-Caneja, C M, Dazzan, P, McGuire, P, Demjaha, A, Ebdrup, B H, Fleischhacker, W W, Kahn, R S & Glenthøj, B Y 2022, ' Scalability of the Positive and Negative Syndrome Scale in first-episode schizophrenia assessed by Rasch models ', Acta Psychiatrica Scandinavica, vol. 146, no. 1, pp. 21-35 . https://doi.org/10.1111/acps.13434
Baandrup, L, Allerup, P, Nielsen, M, Düring, S W, Bojesen, K B, Leucht, S, Galderisi, S, Mucci, A, Bucci, P, Arango, C, Díaz-Caneja, C M, Dazzan, P, McGuire, P, Demjaha, A, Ebdrup, B H, Fleischhacker, W W, Kahn, R S & Glenthøj, B Y 2022, ' Scalability of the Positive and Negative Syndrome Scale in first-episode schizophrenia assessed by Rasch models ', Acta Psychiatrica Scandinavica, vol. 146, no. 1, pp. 21-35 . https://doi.org/10.1111/acps.13434

Objective: Historically, assessment of the psychometric properties of the Positive and Negative Syndrome Scale (PANSS) has had several foci: (1) calculation of reliability indexes, (2) extraction of subdimensions from the scale, and (3) assessment of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e57d0ba33bedae07bcff68e6b76b9d6
https://curis.ku.dk/ws/files/313158672/Acta_Psychiatr_Scand_2022_Baandrup_Scalability_of_the_Positive_and_Negative_Syndrome_Scale_in_first_u2010episode.pdf