Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets

Autor: Kelsey M. Haas, Michael J. McGregor, Mehdi Bouhaddou, Benjamin J. Polacco, Eun-Young Kim, Thong T. Nguyen, Billy W. Newton, Matthew Urbanowski, Heejin Kim, Michael A. P. Williams, Veronica V. Rezelj, Alexandra Hardy, Andrea Fossati, Erica J. Stevenson, Ellie Sukerman, Tiffany Kim, Sudhir Penugonda, Elena Moreno, Hannes Braberg, Yuan Zhou, Giorgi Metreveli, Bhavya Harjai, Tia A. Tummino, James E. Melnyk, Margaret Soucheray, Jyoti Batra, Lars Pache, Laura Martin-Sancho, Jared Carlson-Stevermer, Alexander S. Jureka, Christopher F. Basler, Kevan M. Shokat, Brian K. Shoichet, Leah P. Shriver, Jeffrey R. Johnson, Megan L. Shaw, Sumit K. Chanda, Dan M. Roden, Tonia C. Carter, Leah C. Kottyan, Rex L. Chisholm, Jennifer A. Pacheco, Maureen E. Smith, Steven J. Schrodi, Randy A. Albrecht, Marco Vignuzzi, Lorena Zuliani-Alvarez, Danielle L. Swaney, Manon Eckhardt, Steven M. Wolinsky, Kris M. White, Judd F. Hultquist, Robyn M. Kaake, Adolfo García-Sastre, Nevan J. Krogan

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-27 (2023)

Abstract Influenza A Virus (IAV) is a recurring respiratory virus with limited availability of antiviral therapies. Understanding host proteins essential for IAV infection can identify targets for alternative host-directed therapies (HDTs). Using aff

Externí odkaz: https://doaj.org/article/6403bbe7a8b6480aacd27d46627e36f2

Development of a multi-channel power supply for silicon photo-multipliers used with inorganic scintillators

Autor: Javakhishvili, Otari, Keshelashvili, Irakli, Mchedlishvili, David, Gagoshidze, Mikael, Hahnraths, Tanja, Kacharava, Andro, Metreveli, Zaza, Mueller, Fabian, Sefzick, Thomas, ShergelaShvili, Dimitri, Soltner, Helmut, Stroeher, Hans

The motivation of the current R&D project is based upon the requirements of the JEDI international collaboration aiming to measure Electric Dipole Moments (EDMs) of charged particles in storage rings. One of the most important elements of such an exp

Externí odkaz: http://arxiv.org/abs/2002.01700

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Storage Ring to Search for Electric Dipole Moments of Charged Particles -- Feasibility Study

Autor: Abusaif, F., Aggarwal, A., Aksentev, A., Alberdi-Esuain, B., Andres, A., Atanasov, A., Barion, L., Basile, S., Berz, M., Böhme, C., Böker, J., Borburgh, J., Canale, N., Carli, C., Ciepał, I., Ciullo, G., Contalbrigo, M., De Conto, J. -M., Dymov, S., Felden, O., Gaisser, M., Gebel, R., Giese, N., Gooding, J., Grigoryev, K., Grzonka, D., Tahar, M. Haj, Hahnraths, T., Heberling, D., Hejny, V., Hetzel, J., Hölscher, D., Javakhishvili, O., Jorat, L., Kacharava, A., Kamerdzhiev, V., Karanth, S., Keshelashvili, I., Koop, I., Kulikov, A., Laihem, K., Lamont, M., Lehrach, A., Lenisa, P., Lomidze, I., Lomidze, N., Lorentz, B., Macharashvili, G., Magiera, A., Makino, K., Martin, S., Mchedlishvili, D., Meißner, U. -G., Metreveli, Z., Michaud, J., Müller, F., Nass, A., Natour, G., Nikolaev, N., Nogga, A., Okropiridze, D., Pesce, A., Poncza, V., Prasuhn, D., Pretz, J., Rathmann, F., Ritman, J., Rosenthal, M., Saleev, A., Schott, M., Sefzick, T., Senichev, Y., Shankar, R., Shergelashvili, D., Shmakova, V., Siddique, S., Silenko, A., Simon, M., Slim, J., Soltner, H., Stahl, A., Stassen, R., Stephenson, E., Straatmann, H., Ströher, H., Tabidze, M., Tagliente, G., Talman, R., Uzikov, Y., Valdau, Y., Valetov, E., Vilella, E., Vitz, M., Vossebeld, J., Wagner, T., Weidemann, C., Wirzba, A., Wrońska, A., Wüstner, P., Zupranski, P., Żurek, M.

The proposed method exploits charged particles confined as a storage ring beam (proton, deuteron, possibly $^3$He) to search for an intrinsic electric dipole moment (EDM) aligned along the particle spin axis. Statistical sensitivities could approach

Externí odkaz: http://arxiv.org/abs/1912.07881

Feasibility Study for an EDM Storage Ring

Autor: Abusaif, F., Aggarwal, A., Aksentev, A., Alberdi-Esuain, B., Barion, L., Basile, S., Berz, M., Beyß, M., Böhme, C., Böker, J., Borburgh, J., Carli, C., Ciepał, I., Ciullo, G., Contalbrigo, M., De Conto, J. -M., Dymov, S., Engels, R., Felden, O., Gagoshidze, M., Gaisser, M., Gebel, R., Giese, N., Grigoryev, K., Grzonka, D., Hanraths, T., Hanhart, C., Heberling, D., Hejny, V., Hetzel, J., Hölscher, D., Javakhishvili, O., Kacharava, A., Karanth, S., Käseberg, C., Kamerdzhiev, V., Keshelashvili, I., Koop, I., Kulikov, A., Laihem, K., Lamont, M., Lehrach, A., Lenisa, P., Lomidze, N., Lorentz, B., Macharashvili, G., Magiera, A., Maier, R., Makino, K., Martin, S., Mchedlishvili, D., Meißner, U. -G., Metreveli, Z., Michaud, J., Müller, F., Nass, A., Natour, G., Nikolaev, N., Nogga, A., Pesce, A., Poncza, V., Prasuhn, D., Pretz, J., Rathmann, F., Ritman, J., Rosenthal, M., Saleev, A., Schott, M., Sefzick, T., Senichev, Y., Shergelashvili, D., Shmakova, V., Siddique, S., Silenko, A., Simon, M., Slim, J., Soltner, H., Stahl, A., Stassen, R., Stephenson, E., Straatmann, H., Ströher, H., Tabidze, M., Tagliente, G., Tahar, M., Talman, R., Uzikov, Yu., Valdau, Yu., Valetov, E., Wagner, T., Weidemann, C., Wilkin, C., Wirzba, A., Wrońska, A., Wüstner, P.

This project exploits charged particles confined as a storage ring beam (proton, deuteron, possibly $^3$He) to search for an intrinsic electric dipole moment (EDM, $\vec d$) aligned along the particle spin axis. Statistical sensitivities can approach

Externí odkaz: http://arxiv.org/abs/1812.08535