Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Metka, Novak"'
Autor:
Metka Novak, Barbara Breznik
Publikováno v:
Advances in Cancer Biology - Metastasis, Vol 11, Iss , Pp 100120- (2024)
Externí odkaz:
https://doaj.org/article/ac52fdfe7a6b4cd59345d1de4c287434
Autor:
Bernarda Majc, Anamarija Habič, Marta Malavolta, Miloš Vittori, Andrej Porčnik, Roman Bošnjak, Jernej Mlakar, Alenka Matjašič, Andrej Zupan, Marija Skoblar Vidmar, Tamara Lah Turnšek, Aleksander Sadikov, Barbara Breznik, Metka Novak
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110604- (2024)
Summary: Glioblastoma (GB) is the most common primary malignant brain tumor, characterized by resistance to therapy. Despite aggressive treatment options, GB remains an incurable disease. Invasiveness and heterogeneity are key GB features that cannot
Externí odkaz:
https://doaj.org/article/2811208931514fd98a2e14598552201e
Autor:
Barbara Breznik, Meng-Wei Ko, Christopher Tse, Po-Chun Chen, Emanuela Senjor, Bernarda Majc, Anamarija Habič, Nicolas Angelillis, Metka Novak, Vera Župunski, Jernej Mlakar, David Nathanson, Anahid Jewett
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
“Super-charged” NK cells kill patient-derived glioblastoma stem-like cells (GSLCs) in 2D and 3D tumor models, secrete IFN-γ and upregulate the surface expression of CD54 and MHC class I in GSLCs.
Externí odkaz:
https://doaj.org/article/c555a83978a343d1b3e8050a04378dba
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Venoms are complex mixtures of different molecules and ions. Among them, bioactive peptides have been found to affect cancer hallmarks, such as cell proliferation, cell invasion, cell migration, and can also modulate the immune response of normal and
Externí odkaz:
https://doaj.org/article/825e6917f6d943bcb15cb0097ee33a74
Autor:
Luka Dobovišek, Metka Novak, Fran Krstanović, Simona Borštnar, Tamara Lah Turnšek, Nataša Debeljak
Publikováno v:
Advances in Cancer Biology - Metastasis, Vol 4, Iss , Pp 100038- (2022)
Breast cancer is the most common malignancy in women worldwide. Sixty-five percent of breast cancers are estrogen and/or progesterone receptor positive. Estrogen receptor expression is a prognostic and predictive biomarker of response to endocrine th
Externí odkaz:
https://doaj.org/article/3c505b77b02a4358abb7f632b56736a7
Autor:
Bernarda Majc, Anamarija Habič, Metka Novak, Ana Rotter, Andrej Porčnik, Jernej Mlakar, Vera Župunski, Urša Pečar Fonović, Damijan Knez, Nace Zidar, Stanislav Gobec, Janko Kos, Tamara Lah Turnšek, Anja Pišlar, Barbara Breznik
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1784 (2022)
Glioblastoma (GBM) is the most common and deadly primary brain tumor in adults. Understanding GBM pathobiology and discovering novel therapeutic targets are critical to finding efficient treatments. Upregulation of the lysosomal cysteine carboxypepti
Externí odkaz:
https://doaj.org/article/bb38ce05823b4a539b90db8efbba8a54
Autor:
Andrej Porčnik, Metka Novak, Barbara Breznik, Bernarda Majc, Barbara Hrastar, Neja Šamec, Alja Zottel, Ivana Jovčevska, Miloš Vittori, Ana Rotter, Radovan Komel, Tamara Lah Turnšek
Publikováno v:
Molecules, Vol 26, Iss 17, p 5141 (2021)
Glioblastoma (GB), is the most common and aggressive malignant primary brain tumour in adults. Intra- and inter-tumour heterogeneity, infiltrative GB cell invasion and presence of therapy-resistant GB stem cells (GSCs) represent major obstacles to fa
Externí odkaz:
https://doaj.org/article/a9267ae6953b4ef5a6b6133183695c61
Autor:
Tamara Lah Turnšek, Xuanmao Jiao, Metka Novak, Sriharsha Jammula, Gina Cicero, Anthony W. Ashton, David Joyce, Richard G. Pestell
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4464 (2021)
The mechanisms governing therapeutic resistance of the most aggressive and lethal primary brain tumor in adults, glioblastoma, have increasingly focused on tumor stem cells. These cells, protected by the periarteriolar hypoxic GSC niche, contribute t
Externí odkaz:
https://doaj.org/article/9d56d675644d412a98421716643701d7
Autor:
Cornelis J.F. van Noorden, Vashendriya V.V. Hira, Amber J. van Dijck, Metka Novak, Barbara Breznik, Remco J. Molenaar
Publikováno v:
Cells, Vol 10, Iss 3, p 705 (2021)
Cancer is a redox disease. Low levels of reactive oxygen species (ROS) are beneficial for cells and have anti-cancer effects. ROS are produced in the mitochondria during ATP production by oxidative phosphorylation (OXPHOS). In the present review, we
Externí odkaz:
https://doaj.org/article/0b154c0c44e84e50a3ab7b0d873a4440
Autor:
Tamara T. Lah, Metka Novak, Milagros A. Pena Almidon, Oliviero Marinelli, Barbara Žvar Baškovič, Bernarda Majc, Mateja Mlinar, Roman Bošnjak, Barbara Breznik, Roby Zomer, Massimo Nabissi
Publikováno v:
Cells, Vol 10, Iss 2, p 340 (2021)
Glioblastoma is the most aggressive cancer among primary brain tumours. As with other cancers, the incidence of glioblastoma is increasing; despite modern therapies, the overall mean survival of patients post-diagnosis averages around 16 months, a fi
Externí odkaz:
https://doaj.org/article/cb388de759c140e7867bf6ae9c973589